Wong C, Chen S. The development, application and limitations of breast cancer cell lines to study tamoxifen and aromatase inhibitor resistance. J Steroid Biochem Mol Biol. 2012 Jan 8. PMID: 22265958.
Kanaya N, Kubo M, Liu Z, Chu P, Wang C, Yuan YC, Chen S. Protective effects of white button mushroom (Agaricus bisporus) against hepatic steatosis in ovariectomized mice as a model of postmenopausal women. PLoS One. 2011;6(10):e26654. PMID: 22046322; PMCID: PMC3201963.
Adams LS, Kanaya N, Phung S, Liu Z, Chen S. Whole blueberry powder modulates the growth and metastasis of MDA-MB-231 triple negative breast tumors in nude mice. J Nutr. 2011 Oct;141(10):1805-12. PMID: 21880954; PMCID: PMC3174855.
Hong Y, Rashid R, Chen S. Binding features of steroidal and nonsteroidal inhibitors. Steroids. 2011 Jul;76(8):802-6. PMID: 21420422; PMCID: PMC3253312.
Geisler J, Sasano H, Chen S, Purohit A. Steroid sulfatase inhibitors: promising new tools for breast cancer therapy? J Steroid Biochem Mol Biol. 2011 May;125(1-2):39-45. PMID: 21356310.
Chen S. An "omics" approach to determine the mechanisms of acquired aromatase inhibitor resistance. OMICS. 2011 Jun;15(6):347-52. PMID: 21332390; PMCID: PMC3125554.
Wang Y, Zhou D, Phung S, Masri S, Smith D, Chen S. SGK3 is an estrogen-inducible kinase promoting estrogen-mediated survival of breast cancer cells. Mol Endocrinol. 2011 Jan;25(1):72-82. PMID: 21084382; PMCID: PMC3089033.
Kanaya N, Chen S. Conjugated linoleic acid reduces body weight gain in ovariectomized female C57BL/6J mice. Nutr Res. 2010 Oct;30(10):714-21. PMID: 21056287; PMCID: PMC3000560.
Wang Y, Chen B, Li Y, Zhou D, Chen S. PNRC accumulates in the nucleolus by interaction with B23/nucleophosmin via its nucleolar localization sequence. Biochim Biophys Acta. 2011 Jan;1813(1):109-19. PMID: 20888865; PMCID: PMC3085350.
Hong Y, Chen S. Aromatase, estrone sulfatase, and 17β-hydroxysteroid dehydrogenase: structure-function studies and inhibitor development. Mol Cell Endocrinol. 2011 Jul 4;340(2):120-6. PMID: 20888390; PMCID: PMC3035767.
Chen S, Ye J, Kijima I, Evans D. The HDAC inhibitor LBH589 (panobinostat) is an inhibitory modulator of aromatase gene expression. Proc Natl Acad Sci U S A. 2010 Jun 15;107(24):11032-7. PMID: 20534486; PMCID: PMC2890707.
Adams LS, Phung S, Yee N, Seeram NP, Li L, Chen S. Blueberry phytochemicals inhibit growth and metastatic potential of MDA-MB-231 breast cancer cells through modulation of the phosphatidylinositol 3-kinase pathway. Cancer Res. 2010 May 1;70(9):3594-605. PMID: 20388778; PMCID: PMC2862148.
Masri S, Liu Z, Phung S, Wang E, Yuan YC, Chen S. The role of microRNA-128a in regulating TGFbeta signaling in letrozole-resistant breast cancer cells. Breast Cancer Res Treat. 2010 Nov;124(1):89-99. PMID:20054641.
Adams LS, Zhang Y, Seeram NP, Heber D, Chen S. Pomegranate ellagitannin-derived compounds exhibit antiproliferative and antiaromatase activity in breast cancer cells in vitro. Cancer Prev Res (Phila). 2010 Jan;3(1):108-13. (AACR press release on this paper) PMID: 20051378; PMCID: PMC2805471
Hong Y, Li H, Ye J, Miki Y, Yuan YC, Sasano H, Evans DB, Chen S. Epitope characterization of an aromatase monoclonal antibody suitable for the assessment of intratumoral aromatase activity. PLoS One. 2009 Nov 30;4(11):e8050. PMID: 19956630; PMCID: PMC2778552.
Wong C, Chen S. Heat shock protein 90 inhibitors: new mode of therapy to overcome endocrine resistance. Cancer Res. 2009 Nov 15;69(22):8670-7. PMID: 19861537; PMCID: PMC2784253.
Su B, Chen S. Lead optimization of COX-2 inhibitor nimesulide analogs to overcome aromatase inhibitor resistance in breast cancer cells. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6733-5. PMID: 19854050; PMCID: PMC2783870.
Adams LS, Chen S. Phytochemicals for breast cancer prevention by targeting aromatase. Front Biosci. 2009 Jan 1;14:3846-63. PMID: 19273315.
Masri S, Lui K, Phung S, Ye J, Zhou D, Wang X, Chen S. Characterization of the weak estrogen receptor alpha agonistic activity of exemestane. Breast Cancer Res Treat. 2009 Aug;116(3):461-70. PMID: 18677558.
Adams LS, Phung S, Wu X, Ki L, Chen S. White button mushroom (Agaricus bisporus) exhibits antiproliferative and proapoptotic properties and inhibitsprostate tumor growth in athymic mice. Nutr Cancer. 2008;60(6):744-56.
PMID: 19005974.
Foster PA, Chander SK, Newman SP, Woo LW, Sutcliffe OB, Bubert C, Zhou D, Chen S, Potter BV, Reed MJ, Purohit A. A new therapeutic strategy against hormone-dependent breast cancer: the preclinical development of a dual aromatase and sulfatase inhibitor. Clin Cancer Res. 2008 Oct 15;14(20):6469-77. PMID: 18927286.
Chen B, Wang Y, Kane SE, Chen S. Improvement of sensitivity to tamoxifen in estrogen receptor-positive and Herceptin-resistant breast cancer cells. J Mol Endocrinol. 2008 Nov;41(5):367-77. PMID: 18768663.
Lisztwan J, Pornon A, Chen B, Chen S, Evans DB. The aromatase inhibitor letrozole and inhibitors of insulin-like growth factor I receptor synergistically induce apoptosis in in vitro models of estrogen-dependent breast cancer. Breast Cancer Res. 2008;10(4):R56. PMID: 18611244; PMCID: PMC2575527.
Masri S, Phung S, Wang X, Wu X, Yuan YC, Wagman L, Chen S. Genome-wide analysis of aromatase inhibitor-resistant, tamoxifen-resistant, and long-term estrogen-deprived cells reveals a role for estrogen receptor. Cancer Res. 2008 Jun 15;68(12):4910-8 PMID: 18559539.
Lui K, Tamura T, Mori T, Zhou D, Chen S. MCF-7aro/ERE, a novel cell line for rapid screening of aromatase inhibitors, ERalpha ligands and ERRalpha ligands. Biochem Pharmacol. 2008 Jul 15;76(2):208-15. (evaluated by Martin Van den Berg: http://www.f1000biology.com/article/id/1118894/evaluation). PMID:18550029; PMCID: PMC2587126.
This is a partial list. Full publications list available upon request. Information on this page may be self-reported and is subject to change at any time. Last updated: 4/12.
