Yuan, H., Wang, Z., Gao, C., Chen, W., Huang, Q., Yee, J.K., Bhatia, R., and
Chen, W.Y. (2009) BCR-ABL gene expression is required for its mutations in a novel KCL-22 cell culture model for acquired resistance of chronic myelogenous leukemia. J Biol Chem (JBC Papers in Press. The latest version is at
http://www.jbc.org/cgi/doi/10.1074/jbc.M109.039206)
Chen W.Y., Wang, D.H., Chiu, R.W., Lou, J.Y., Gu, W, and Baylin, S.B. (2005) Tumor suppressor HIC1 directly regulates SIRT1 deacetylase to modulate p53-dependent apoptotic DNA damage responses. Cell, 123:437-448.
Chen, W.Y., Cooper, T.K., Zahnow, C.A., Overholtzer, M, Zhao, Z, Ladanyi, M., Karp, .E., Gokgoz, N., Wunder, J.S., Andrulis, I.L., Levine, A.J., Mankowski, J.L., & Baylin, S.B. (2004) Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis. Cancer Cell, 6:387-398.
Chen W.Y., Zeng X., Carter M.G., Morrell C.N., Chiu Yen R.W., Esteller M., Watkins D.N., Herman J.G., Mankowski J.L. & Baylin S.B. (2003) Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors. Nat Genet, 33, 197-202.
Chen W.Y. & Townes T.M. (2000) Molecular mechanism for silencing virally transduced genes involves histone deacetylation and chromatin condensation. Proc Natl Acad Sci U S A, 97, 377-382.
Chen W.Y., Wu X., Levasseur D.N., Liu H., Lai L., Kappes J.C. & Townes T.M. (2000) Lentiviral vector transduction of hematopoietic stem cells that mediate long-term reconstitution of lethally irradiated mice. Stem Cells, 18, 352-359.
Zhao W., Noya F.,
Chen W.Y., Townes T.M., Chow L.T. & Broker T.R. (1999) Trichostatin A up-regulates human papillomavirus type 11 upstream regulatory region-E6 promoter activity in undifferentiated primary human keratinocytes. J Virol, 73, 5026-5033.
Chen W.Y., Bailey E.C., McCune S.L., Dong J.Y. & Townes T.M. (1997) Reactivation of silenced, virally transduced genes by inhibitors of histone deacetylase. Proc Natl Acad Sci U S A, 94, 5798-5803.
This is a partial list. Full publications list available upon request. Information on this page may be self-reported and subject to change at any time. Last updated 01/10.
