Morgan RM, Couture LA, Elroy-Stein O, Moss B, Anderson WF. Retroviral vectors containing internal ribosome entry sites: Development of a polycistronic gene transfer system and applications to human gene therapy. Nucleic Acids Res, 1992, 20(6):1293-1299.
Couture LA, Lehman JM. Polyomavirus enhancer requirements for expression in embryonal carcinoma cells. Int J Dev Biol. 1993 Mar;37(1):125-33.
Morgan RM, Nussbaum O, Meunchau DD, Shu L, Couture LA, Anderson WF. Analysis of the functional and host range-determining regions of the murine ecotropic and amphotropic retrovirus envelope proteins. J Virol. 1993 Aug;67(8):4712-21.
Rich DP, Couture LA, Cardoza LM, Guiggio VM, Armentano D, Espino PC, Hehir K, Welsh MJ, Smith AE, Gregory RJ. Development and analysis of recombinant adenoviruses for gene therapy of cystic fibrosis. Hum Gene Ther. 1993 Aug;4(4):461-76.
Zabner J, Couture LA, Gregory RJ, Graham SM, Smith AE, Welsh MJ. Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis. Cell. 1993 Oct 22;75(2):207-16.
Zabner J, Petersen DM, Puga AP, Graham SM, Couture LA, Keyes LD, Lukason MJ, St George JA, Gregory RJ, Smith AE, et al. Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats. Nat Genet. 1994 Jan;6(1):75-83.
Zabner J, Couture LA, Smith AE, Welsh MJ. Correction of cAMP-stimulated fluid secretion in cystic fibrosis airway epithelia: efficiency of adenovirus-mediated gene transfer in vitro. Hum Gene Ther. 1994 May;5(5):585-93.
Couture LA, Mullen CA, Morgan RA. Retroviral vectors containing chimeric promoter/ enhancer elements exhibit cell-type-specific gene expression. Hum Gene Ther. 1994 Jun;5(6):667-77.
Jomary C, Piper TA, Dickson G, Couture LA, Smith AE, Neal MJ, Jones SE. Adenovirus-mediated gene transfer to murine retinal cells in vitro and in vivo. FEBS Lett. 1994 Jun 27;347(2-3):117-22.
Thompson JD, Macejak D, Couture LA, Stinchcomb DT. Ribozymes in gene therapy. Nature Medicine. 1995 Mar;1(3):277-8.
McCray PB, Armstrong K, Zabner J, Smith BA, Robillard JE, Couture LA, Smith AE, Welsh MJ. Adenoviral-mediated gene transfer to fetal pulmonary epithelia. J Clinical Invest. 1995, Jun;95(6):2620-2632.
Thompson JD, Ayers DF, Malmstrom TA, McKenzie TL, Ganousis L, Chowrira BM, Couture LA, Stinchcomb DT. Improved accumulation and activity of ribozymes expressed from a tRNA-based polymerase III promoter. Nucleic Acids Res. 1995 Jun 25;23(12):2259-68.
Zhai Y, Yang JC, Kawakami Y, Spiess P, Wadsworth SC, Cardoza LM, Couture LA, Smith AE, Rosenberg SA. Antigen-specific tumor vaccines. Development and characterization of recombinant adenoviruses encoding MART1 or gp100 for cancer therapy. J Immunol. 1996 Jan 15;156(2):700-10.
Couture LA, Stinchcomb DT. Anti-gene therapy: the use of ribozymes to inhibit gene function. Trends Genet. 1996 Dec;12(12):510-5. Review.
Hehir KM, Armentano D, Cardoza LM, Choquette TL, Berthelette PB, White GA, Couture LA, Everton MB, Keegan J, Martin JM, Pratt DA, Smith MP, Smith AE, Wadsworth SC. Molecular characterization of replication-competent variants of adenovirus vectors and genome modifications to prevent their occurrence. J Virol. 1996 Dec;70(12):8459-67.
Kozarsky KF, Couture LA. Message therapy: gene therapy that targets mRNA sequence and stability. Am J Hum Genet. 1997 Oct;61(4):790-4. Review. No abstract available.
Jarvis T, Macejak D, Couture LA. Ribozyme-mediated inhibition of cell proliferation: A model for identifying and refining a therapeutic ribozyme. Molecular Medicine Vol. 11: Therapeutic Applications of Ribozymes. KJ Scanlon ed, Humana Press Inc. 1998, 329-339.
Ragheb JA, Couture LA, Mullen C, Ridgway A, Morgan RA. Inhibition of human immunodeficiency virus type1 by Tat/Rev-regulated expression of cytosine deaminase, interferon alpha2, or diphtheria toxin compared with inhibition by transdominant Rev. Hum Gene Ther. 1999 Jan 1;10(1):103-12.
Macejak DG, Lin H, Webb S, Chase J, Jensen K, Jarvis TC, Leiden JM, Couture LA. Adenovirus-Mediated Expression of a Ribozyme to c-myb mRNA Inhibits Smooth Muscle Cell Proliferation and Neointima Formation In Vivo. J Virol. 1999, Sept;73(9):7745-51.
Couture LA, Rossi J. Intracellular Ribozyme Applications: Principles and Protocols. Wymondham, Norfolk, England : Horizon Scientific Press, c1999.
Johnson LE, Frye TP, Arnot AR, Marquette C, Couture LA, Gendron-Fitzpatrick A, McNeel DG. Safety and immunological efficacy of a prostate cancer plasmid DNA vaccine encoding prostatic acid phosphatase (PAP). Vaccine. 2006 Jan 16;24(3):293-303. Epub 2005 Aug 9.
This is a partial list. Full publications list available upon request. Information on this page may be self-reported. Last updated: 07/08.
