Singhal SS, Figarola J, Singhal J, Leake K, Nagaprashantha L, Lincoln C, Gabriel Gugiu B, Horne D, Jove R, Awasthi S, Rahbar S. 1,3-Bis(3,5-dichlorophenyl) urea compound ‘COH-SR4’ inhibits proliferation and activates apoptosis in melanoma. Biochem. Pharmacol. 2012; 84 (11); 1419-1427.

Figarola, JL, Weng, Y, Lincoln, C, Horne, D, Rahbar, S, Novel dichlorophenyl urea compounds inhibit proliferation of human leukemia HL-60 cells by inducing cell cycle arrest, differentiation and apoptosis. Invest. New Drugs 2012; 30 (4), 1413-25.

Nam, S, Xie, J, Perkins, A, Ma, Y, Yang, F, Wu, J., Wang, Y, Xu, R. Z., Huang, W., Horne, DA, Jove, R., Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells. Molecular oncology 2012; 6 (5), 484-93.

Singhal, SS, Figarola, J, Singhal, J, Leake, K, Nagaprashantha, L, Lincoln, C, Gabriel Gugiu, B, Horne, D, Jove, R, Awasthi, S, Rahbar, S; 1,3-Bis(3,5-dichlorophenyl) urea compound 'COH-SR4' inhibits proliferation and activates apoptosis in melanoma. Biochem. Pharmacol. 2012.

Xie J, Ma Y, Horne DA. Asymmetric Synthesis of the Core Structure of Leucosceptroids A-D. J Org Chem 2011; 76: 6169-76.

Xie J, Ma Y, Horne DA. Total synthesis of the proposed structure of iriomoteolide-1a. Tetrahedron 2011; 67: 7485-501.

Ma Y, Kowolik CM, Swiderski PM, Kortylewski M, Yu H, Horne DA, Jove R, Caballero OL, Simpson AJG, Lee FT, Pillay V, Scott AM. Humanized Lewis-Y Specific Antibody Based Delivery of STAT3 siRNA. ACS Chem. Biol 2011 DOI: 10.1021/cb200176v

Buettner R, Corzano R, Rashid R, Lin JP, Senthil M, Hedvat M, Schroeder A, Mao A, Herrmann A, Yim J, Li HZ, Yuan YC, Yakushijin KI, Yakushijin F, Vaidehi N, Moore R, Gugiu G, Lee TD, Yip R, Chen Y, Jove R, Horne D, Williams JC. Alkylation of Cysteine 468 in Stat3 Defines a Novel Site for Therapeutic Development. ACS Chem. Biol 2011; 6: 432-43.

Xie J, Ma Y, Horne DA. Total synthesis of the proposed structure of iriomoteolide-1a. Chem. Commun. (Cambridge, U. K.) 2010; 46: 4770-72.

Miyake F, Hashimoto M, Tonsiengsom S, Yakushijin K, Horne DA. Synthesis of 5-(3-indolyl)oxazole natural products. Structure revision of Almazole D. Tetrahedron 2010, 66: 4888-93.

Ma Y, Nam S, Jove R, Yakushijin K, Horne DA. Synthesis and anticancer activities of ageladine A and structural analogs. Bioorg. Med. Chem. Lett. 2010; 20: 83-86.

Lee H, Deng J, Kujawski M, Yang C, Liu Y, Herrmann A, Kortylewski M, Horne D, Somlo G, Forman S, Jove R, Yu H. STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors. Nat. Med. (N. Y., NY, U. S.) 2010; 16: 1421-28.

Xie J, Ma Y, Horne DA. Asymmetric Synthesis of the C(7)-C(23) Fragment of Iriomoteolide-1a. Org. Lett. 2009; 11: 5082-84.

Xie J, Horne D. Stereoselective synthesis of iriomoteolide-1a hemiketal core. Tetrahedron Lett. 2009; 50: 4485-87.

Ma Y, Yakushijin K, Miyake F, Horne D. A concise synthesis of indolic enamides: coscinamide A, coscinamide B, and igzamide. Tetrahedron Lett. 2009; 50: 4343-45.

Tonsiengsom F, Miyake FY, Yakushijin K, Horne DA. Reduction of 2,5-bis(3'-indolyl)pyrazines to 2,5-bis(3'-indolyl)piperazines: synthesis of bisindolylpiperazine marine alkaloids dragmacidin A, B, and C. Synthesis 2006; 49-54.

Miyake FY, Yakushijin K, Horne DA. Biomimetic synthesis of grossularines-1. Angew. Chem., Int. Ed. 2005; 44: 3280-82.

Shimizu H, Shimizu K, Kubodera N, Yakushijin K, Horne DA. Efficient modification of steroid 20S-hydroxy functionality for industrial preparation of 1α,25-dihydroxy-22-oxavitamin D3, Maxacalcitol. Tetrahedron Lett. 2004; 45: 1347-50.

Shimizu H, Shimizu K, Kubodera N, Yakushijin K, Horne DA. Regioselective cleavage of trisubstituted epoxy-linkage using lithium trialkylborohydride reagents: A new route to the key intermediate of maxacalcitol. Heterocycles 2004; 63: 1335-43.

Miyake FY, Yakushijin K, Horne DA. A concise synthesis of spirotryprostatin A. Org. Lett. 2004; 6: 4249-51.

Miyake FY, Yakushijin K, Horne DA. Preparation and synthetic applications of 2-halotryptophan methyl esters: Synthesis of spirotryprostatin B. Angewandte Chemie-International Edition 2004; 43: 5357-60.

Miyake FY, Yakushijin K, Horne DA. Preparation and synthetic applications of 2-halotryptamines: Synthesis of elacomine and isoelacomine. Org. Lett. 2004; 6: 711-13.

Castedo M, Perfettini JL, Roumier T, Yakushijin K, Horne D, Medema R, Kroemer G. The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe. Oncogene 2004; 23: 4353-61.

Castedo M, Perfettini JL, Roumier T, Valent A, Raslova H, Yakushijin K, Horne D, Feunteun J, Lenoir G, Medema R, Vainchenker W, Kroemer G. Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy. Oncogene 2004; 23: 4362-70.

Wiese KJ, Yakushijin K, Horne DA. Synthesis of dibromophakellstatin and dibromoisophakellin. Tetrahedron Lett. 2002, 43 (29), 5135-36.

Miyake FY, Yakushijin K, Horne DA. Synthesis of marine sponge bisindole alkaloids dihydrohamacanthins. Org. Lett. 2002; 4: 941-3.

Barrios Sosa AC, Yakushijin K, Horne DA. Synthesis of axinohydantoins. J. Org. Chem. 2002; 67: 4498-5000.

Miyake FY, Yakushijin K, Horne DA., A facile synthesis of dragmacidin B and 2,5-bis(6 '-bromo-3 '-indolyl)piperazine. Org. Lett. 2000; 2: 3185-87.

Miyake FY, Yakushijin K, Horne DA. A concise synthesis of topsentin A and nortopsentins B and D. Org. Lett. 2000; 2: 2121-23.

Barrios Sosa AC, Yakushijin K, Horne DA. Controlling cyclizations of 2-pyrrolecarboxamidoacetals. Facile solvation of [beta]-amido aldehydes and revised structure of synthetic homolongamide. Tetrahedron Lett. 2000; 41: 4295-99.

Barrios Sosa AC, Yakushijin K, Horne DA. A practical synthesis of (Z)-debromohymenialdisine. J. Org. Chem. 2000; 65: 610-1.

Barrios Sosa AC, Yakushijin K, Horne DA. Synthesis of slagenins A, B, and C. Org. Lett. 2000; 2; 3443-44.

This is a partial list. Full publications list available upon request. Information on this page may be self-reported and is subject to change at any time. Last updated: 09/11.