Lee CG, Kima YW, Kimb EH, Meng Z, Huang W, Hwangb SJ, Kim SG. FXR Protects Hepatocytes from Injury by Repressing miR-199a-3p, which Increases Levels of LKB1. Gastroenterology, 2012 Jan 18. [Epub ahead of print]
Zhang L, Li T, Yu D, Forman BM, Huang W. FXR Protects Lung from Lipopolysaccharide-Induced Acute Injury. Mol Endocrinol. 2011 Dec 1; [Epub ahead of print]
Wang YD, Chen WD, Yu D, Forman BM, Huang W. The G-protein coupled bile acid receptor Gpbar1 (TGR5) negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappaB. Hepatology 2011; 54(4):1421-32.
Meng, Z., Liu, N., Fu, X., Wang, X., Zhang, L., Chen, W., Wang, Y., Forman, B.M., Huang, W. Defective bile acid signaling results in impaired liver regeneration in CYP27 knockout mice. J. Hepatol. 2011; 5594:885-95.
Meng Z., Fu X., Chen X, Zeng S., Tian Y., Jove R., Xu R., Huang W., miR-194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells. Hepatology 2010; 52:2148-57.
Meng Z., Wang Y., Wang L., Liu N., Huang X., Pan H, Liu L., Wagman L. and Huang W., FXR regulates liver repair after CCl4-induced toxic injury. Mol Endocrinol. 2010; 24:886-97.
Chen W., Wang Y., Zhang L., Shiah S., Wang M., Yang F., Yu D., Forman B.M. and Huang W., Activation of farnesoid X receptor alleviates age-related proliferation defects in regenerating mouse livers. Hepatology 2009; 51:953-62.
Dong B., Saha P.K., Huang W., Chen W., Abu-Elheiga L.A., Wakil S.J., Stevens R.D., Ilkayeva O., Newgard C.B., Chan L., and Moore D.D. Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease. Proc Natl Acad Sci U S A. 2009; 106:18831-6.
Zhang L., Huang X., Meng Z., Dong B., Shiah S, Moore D.D., Huang W., (2009) Significance and mechanism of CYP7a1 gene regulation in acute phase of liver regeneration. Mol Endocrinol. 23:137-45.
Wang Y., Chen W., Huang M., Yu D., Forman B.M., and Huang, W. (2008) Farnesoid X receptor antagonizes NF-kB in hepatic inflammatory response. Hepatology 48:1632-43.
Wang Y., Yang F., Chen W., Huang X., Lai L., Forman B.M., and Huang, W. (2008) Farnesoid X Receptor (FXR) Protects Liver Cells from Apoptosis Induced by Serum Deprivation in vitro and Fasting in vivo. Mol Endocrinol. 22:1622-32.
Amador-Noguez D., Dean A., Huang W., Setchell K., Moore D., and Darlington G. (2007) Alterations in xenobiotic metabolism in the long-lived Little mice. Aging Cell 6: 453-70.
Yang F., Huang X., Yi T., Yen Y., Moore D.D., and Huang W. (2007) Spontaneous development of liver tumors in the absence of the bile acid receptor Farnesoid X Receptor. Cancer Res. 67: 863-867.
Baskin-Bey E., Huang W., Ishimura N., Bronk S.F., Werneburg N., Moore D.D., and Gores G. J. (2006) Constitutive androstane receptor (CAR) ligand, TCPOBOP, attenuates Fas-induced murine liver injury by altering Bcl-2 proteins. Hepatology. 44:252-262.
Huang W., Ma K., Zhang J., Qatanani M., Cuvillier J., Liu J., Dong B., Huang X., and Moore D.D. (2006) Nuclear receptor dependent bile acid signaling is required for normal liver regeneration. Science (Article) 312:233-236.
This is a partial list. Full publications list available upon request. Information on this page may be self-reported and is subject to change at any time. Last updated: 04/13