Somlo, G., Martel, C.L., Lau, S.K., Frankel, P., Ruel, C., Gu, L., Hurria, A., Chung, C., Luu, T., Morgan, R., Leong, L., Koczywas, M., McNamara, M., Russell, C.A., Kane, S.E. (2012) A phase I/II prospective, single arm trial of gefitinib, trastuzumab and docetaxel in patients with stage IV HER-2 positive metastatic breast cancer. Breast Cancer Res. Treat. 131: 899-906.

Gu, L., Lau, S.K., Loera, S., Somlo, G. and Kane, S.E. (2009) Protein kinase A activation confers resistance to trastuzumab in human breast cancer cell lines. Clin. Cancer Res. 15: 7196-7206.

Gu, L., Waliany, S. and Kane, S.E. (2009) Darpp-32 and its truncated variant t-Darpp have antagonistic effects on breast cancer cell growth and Herceptin resistance. PLoS ONE 4: e6220.

Gu, L., Tsark, W.M., Brown, D.A., Blanchard, S., Synold, T.W. and Kane, S.E. (2009) A new model for studying tissue-specific mdr1a expression in vivo by live imaging. Proc. Natl. Acad. Sci. USA 106: 5394-5399.

Sadava, D., Still, D., Mudry, R.R. and Kane, S.E. (2009) Effect of Ganoderma extracts on drug-sensitive and multidrug resistant small-cell lung carcinoma cells. Cancer Lett. 277: 182-189.

Sadava, D., Whitlock, E. and Kane, S.E. (2007) The green tea polyphenol, epigallocatechin-3-gallate inhibits telomerase and induces apoptosis in drug-resistant lung cancer cells.  Biochem. Biophys. Res. Comm.  360: 233-237.

Kane, S.E. (2006) Cancer therapies targeted to the epidermal growth factor receptor and its family members. Expert Opin. Ther. Patents 16: in press. Invited review.

Chan, C.T., Metz, M.Z. and Kane, S.E. (2005) Differential sensitivities of trastuzumab (Herceptin)-resistant human breast cancer cells to phosphoinositide-3 kinase (PI-3K) and epidermal growth factor receptor (EGFR) kinase inhibitors.  Breast Cancer Res. Treat.  91: 187-201.

Schwarz, R.E., Donohue, C.A., Sadava, D., and Kane, S.E. (2003) Pancreatic cancer in vitro toxicity mediated by Chinese herbs SPES and PC-SPES: implications for monotherapy and combination treatment.  Cancer Lett. 189: 59-68.

Sadava, D., Coleman, A.B. and Kane, S.E. (2002) Liposomal daunorubicin overcomes drug resistance in human breast, ovarian and lung carcinoma cells. J. Liposome Res. 12: 301-309.

Coleman, A.B., Metz, M.Z., Donohue, C.A., Schwarz, R.E., and Kane, S.E. (2002) Chemosensitization by fibroblast growth factor-2 is not dependent on proliferation, S-phase accumulation or p53 status.  Biochem. Pharmacol.  64: 1111-1123.

Sadava, D., Ahn, J., Zhan, M., Pang, M.-L., Ding, J., and Kane, S.E. (2002) Effects of four Chinese herbal extracts on drug-sensitive and multidrug-resistant small-cell lung carcinoma cells.  Cancer Chemother. Pharmacol. 49: 261-266.

Sadava, D., Phillips, T., Lin, C. and Kane, S.E. (2002) Transferrin overcomes drug resistance to artemisinin in human small-cell lung carcinoma cells.  Cancer Lett. 179: 151-156.

Kane, S.E., Matsumoto, L., Metz, M.Z., Donohue, C.A., Lingeman, R.G., Lin, S.W., and Doroshow, J.H. (2001) MDR1 bicistronic vectors:  Analysis of selection stringency, amplified gene expression, and vector stability in cell lines.  Biochem. Pharmacol. 62: 693-704.

Coleman, A.B., Momand, J., and Kane, S.E. (2000) Basic fibroblast growth factor sensitizes NIH 3T3 cells to apoptosis induced by cisplatin.  Molec. Pharmacol. 57: 324-333.

This is a partial list. Full publications list available upon request. Information on this page may be self-reported and is subject to change at any time. Last updated: 5/12