Parsons, J. L., B. D. Preston, T. R. O'Connor, and G. L. Dianov. 2007. DNA polymerase delta-dependent repair of DNA single strand breaks containing 3'-end proximal lesions. Nucleic Acids Res 35:1054-63.
Lee, H. W., H. J. Lee, C. M. Hong, D. J. Baker, R. Bhatia, and T. R. O'Connor. 2007. Monitoring repair of DNA damage in cell lines and human peripheral blood mononuclear cells. Anal Biochem 365:246-59.
Baker, D. J., G. Wuenschell, L. Xia, J. Termini, S. E. Bates, A. D. Riggs, and T. R. O'Connor. 2007. Nucleotide Excision Repair Eliminates Unique DNA-Protein Cross-links from Mammalian Cells. J Biol Chem 282:22592-604.
O'Connor, T. R. 2006. Repair of small DNA alkylating agent damage, p. 339-388. In W. Siede, P. W. Doetsch, and Y. W. Kow (ed.), Recognition of DNA Damage. Taylor and Francis, New York.
Dong, M., V. Vongchampa, L. Gingipalli, J. F. Cloutier, Y. W. Kow, T. O'Connor, and P. C. Dedon. 2006. Development of enzymatic probes of oxidative and nitrosative DNA damage caused by reactive nitrogen species. Mutat Res 594:120-34.
Yoon, J. H., P. Singh, D. H. Lee, J. Qiu, S. Cai, T. R. O'Connor, Y. Chen, B. Shen, and G. P. Pfeifer. 2005. Characterization of the 3' 5' exonuclease activity found in human nucleoside diphosphate kinase 1 (NDK1) and several of its homologues. Biochemistry 44:15774-86.
Xia, L., L. Zheng, H. W. Lee, S. E. Bates, L. Federico, B. Shen, and T. R. O'Connor. 2005. Human 3-Methyladenine-DNA Glycosylase: Effect of Sequence Context on Excision, Association with PCNA, and Stimulation by AP Endonuclease. J Mol Biol 346:1259-74.
Lee, H.-W., G. E. Wuenschell, S.-H. Park, L. Xia, J. Termini, and T. R. O'Connor. 2005. Repair of deaminated purines in human cells. Manuscript in preparation.
Lee, D. H., S. G. Jin, S. Cai, Y. Chen, G. P. Pfeifer, and T. R. O'Connor. 2005. Repair of methylation damage in DNA and RNA by mammalian AlkB homologues. J Biol Chem 280:39448-59.
Campalans, A., S. Marsin, Y. Nakabeppu, T. R. O'Connor, S. Boiteux, and J. P. Radicella. 2005. XRCC1 interactions with multiple DNA glycosylases: a model for its recruitment to base excision repair. DNA Repair (Amst) 4:826-35.
Bates, S. E., N. Y. Zhou, L. E. Federico, L. Xia, and T. R. O'Connor. 2005. Repair of cyclobutane pyrimidine dimers or dimethylsulfate damage in DNA is identical in normal or telomerase-immortalized human skin fibroblasts. Nucleic Acids Res 33:2475-85.
Reddy, P., P. Jaruga, T. O'Connor, H. Rodriguez, and M. Dizdaroglu. 2004. Overexpression and rapid purification of Escherichia coli formamidopyrimidine-DNA glycosylase. Protein Expr Purif 34:126-33.
Dherin, C., D. Gasparutto, T. R. O'Connor, J. Cadet, and S. Boiteux. 2004. Excision by the human methylpurine DNA N-glycosylase of cyanuric acid, a stable and mutagenic oxidation product of 8-oxo-7,8-dihydroguanine. Int J Radiat Biol 80:21-7.
Zhou, N. Y., S. E. Bates, M. Bouziane, A. Stary, A. Sarasin, and T. R. O'Connor. 2003. Efficient repair of cyclobutane pyrimidine dimers at mutational hot spots is restored in complemented Xeroderma pigmentosum group C and trichothiodystrophy/xeroderma pigmentosum group D cells. J Mol Biol 332:337-51.
Yoon, J. H., S. Iwai, T. R. O'Connor, and G. P. Pfeifer. 2003. Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair. Nucleic Acids Res 31:5399-404.
Wuenschell, G. E., T. R. O'Connor, and J. Termini. 2003. Stability, Miscoding Potential, and Repair of 2'-Deoxyxanthosine in DNA: Implications for Nitric Oxide-Induced Mutagenesis. Biochemistry 42:3608-16.
O'Connor, T. R., H.-H. Chen, S.-M. Dai, S. D. Flanagan, S. A. Akman, G. P. Holmquist, H. Rodriguez, and A. D. Riggs. 2003. Mapping Oxidative DNA Damage at Nucleotide Resolution in Mammalian Cells, p. 257-274. In R. G. Cutler and H. Rodriguez (ed.), Oxidative Stress and Aging: Advances in Basic Science, Diagnostics, and Intervention, vol. 1. World Scientific Publishing Company, River Edge, NJ USA.
O'Connor, T. R. 2003. Human Genomic DNA Repair Enzymes, p. 719-743. In R. G. Cutler and R. H.R. (ed.), Mammalian Cells in Oxidative Stress and Aging: Advances in Basic Science, Diagnostics, and Intervention, vol. 1. World Scientific Publishing Company, River Edge, NJ USA.
Lee, D. H., T. R. O'Connor, and G. P. Pfeifer. 2002. Oxidative DNA damage induced by copper and hydrogen peroxide promotes CG-->TT tandem mutations at methylated CpG dinucleotides in nucleotide excision repair-deficient cells. Nucleic Acids Res 30:3566-73.
Jiang, C. L., S. G. Jin, D. H. Lee, Z. J. Lan, X. Xu, T. R. O'Connor, P. E. Szabo, J. R. Mann, A. J. Cooney, and G. P. Pfeifer. 2002. MBD3L1 and MBD3L2, Two New Proteins Homologous to the Methyl-CpG-Binding Proteins MBD2 and MBD3: Characterization of MBD3L1 as a Testis-Specific Transcriptional Repressor. Genomics 80:621-9.
Dai, S. M., T. R. O'Connor, G. P. Holmquist, A. D. Riggs, and S. D. Flanagan. 2002. Ligation-mediated PCR: robotic liquid handling for DNA damage and repair. Biotechniques 33:1090-7.
Xia, L., and T. R. O'Connor. 2001. DNA glycosylase activity assay based on streptavidin paramagnetic bead substrate capture. Anal Biochem 298:322-6.
Cloutier, J. F., R. Drouin, M. Weinfeld, T. R. O'Connor, and A. Castonguay. 2001. Characterization and mapping of DNA damage induced by reactive metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) at nucleotide resolution in human genomic DNA. J Mol Biol 313:539-57.
Cloutier, J. F., A. Castonguay, T. R. O'Connor, and R. Drouin. 2001. Alkylating agent and chromatin structure determine sequence context- dependent formation of alkylpurines. J Mol Biol 306:169-88.
Yoon, J. H., C. S. Lee, T. R. O'Connor, A. Yasui, and G. P. Pfeifer. 2000. The DNA damage spectrum produced by simulated sunlight. J Mol Biol 299:681-93.
Miao, F., M. Bouziane, R. Dammann, C. Masutani, F. Hanaoka, G. Pfeifer, and T.R. O'Connor. 2000. 3-Methyladenine-DNA glycosylase (MPG protein) interacts with human RAD23 proteins. J Biol Chem 275:28433-8.
Bouziane, M., F. Miao, S.E. Bates, L. Somsouk, B.C. Sang, M. Denissenko, and T. R. O'Connor. 2000. Promoter structure and cell cycle dependent expression of the human methylpurine-DNA glycosylase gene. Mutat Res 461:15-29.
Akman, S.A., T. R. O'Connor, and H. Rodriguez. 2000. Mapping oxidative DNA damage and mechanisms of repair. Ann N Y Acad Sci 899:88-102.
Miao, F., M. Bouziane, and T. R. O'Connor. 1998. Interaction of the recombinant human methylpurine-DNA glycosylase (MPG protein) with oligodeoxyribonucleotides containing either hypoxanthine or abasic sites. Nucleic Acids Res 26:4034-41.
O'Connor, T. R., R. J. Graves, G. de Murcia, B. Castaing, and J. Laval. 1993. Fpg protein of Escherichia coli is a zinc finger protein whose cysteine residues have a structural and/or functional role. J Biol Chem 268:9063-70.
Graves, R. J., I. Felzenszwalb, J. Laval, and T. R. O'Connor. 1992. Excision of 5'-terminal deoxyribose phosphate from damaged DNA is catalyzed by the Fpg protein of Escherichia coli. J Biol Chem 267:14429-35.
O'Connor, T. R., and F. Laval. 1991. Human cDNA expressing a functional DNA glycosylase excising 3- methyladenine and 7-methylguanine. Biochem. Biophys. Res. Commun. 176:1170-7.
O'Connor, T. R., and F. Laval. 1990. Isolation and structure of a cDNA expressing a mammalian 3- methyladenine-DNA glycosylase. Embo J 9:3337-42.
Boiteux, S., T. R. O'Connor, F. Lederer, A. Gouyette, and J. Laval. 1990. Homogeneous Escherichia coli FPG protein. A DNA glycosylase which excises imidazole ring-opened purines and nicks DNA at apurinic/apyrimidinic sites. J Biol Chem 265:3916-22.
O'Connor, T. R., and J. Laval. 1989. Physical association of the 2,6-diamino-4-hydroxy-5N- formamidopyrimidine-DNA glycosylase of Escherichia coli and an activity nicking DNA at apurinic/apyrimidinic sites. Proc Natl Acad Sci U S A 86:5222-6.
Boiteux, S., T. R. O'Connor, and J. Laval. 1987. Formamidopyrimidine-DNA glycosylase of Escherichia coli: cloning and sequencing of the fpg structural gene and overproduction of the protein. Embo J 6:3177-83.
Moller, M. R., M. A. Bruck, T. O'Connor, J. Armatis, F.J., E. A. Knolinski, N. Kottmair, and R. S. Tobias. 1980. Heavy metal nucleotide interactions. Factors governing selectivity in binding reactions. J.Am.Chem.Soc. 102:4589-4598.
O'Connor, T. R., D. S. Kang, and R. D. Wells. 1986. Thermodynamic parameters are sequence-dependent for the supercoil- induced B to Z transition in recombinant plasmids. J Biol Chem 261:13302-8.
This is a partial list. Full publications list available upon request. Information on this page may be self-reported and subject to change at any time. Las updated 07/08.