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 Selected Publications

Shum, K., Zhou, J., and Rossi, J.J. (2013) Aptamer-based therapeutics: New strategies to fight infectious disease.  Pharmaceuticals (In Preparation)

Rossi, J.J., McCaffrey, A., Snead, N. and Escamilla-Powers, J. (2013) Applying 5’ UNA to improve otherwise poor siRNAs.  Mol. Ther.-Nucl. Acid.  (In Revision)

Zhou, J., Neff, C. P., Swiderski, P., Li, H., Smith, D.D., Aboellail, T., Remling-Mulder, L., Akkina, R. and Rossi, J.J. (2013) Functional in vivo delivery of multiplexed anti-HIV-1 siRNAs via a chemically synthesized aptamer with a sticky bridge. Mol. Ther. 21: 192-200.  PMCID: PMC3538316

Zhou, J., Neff, C.P. Liu, X., Zhang, J., Li, H., Smith, D.D., Peng, L., Akkina, R. and Rossi, J.J. (2011) Systemic  Administration of Combinatorial dsiRNAs via Nanoparticles Efficiently Suppresses HIV-1  Infection in Humanized Mice.  Mol. Ther. 19: 2228-2238. PMCID: PMC3242666

Zhou, J. and Rossi, J.J. (2010) Aptamer-targeted cell-specific RNA interference.  Silence J., 1: 1-10.  PMCID: PMC2835998

Burnett, J.C., Lim, K.I., Calafi, A., Rossi, J.J., Schaffer, D.V. and Arkin, A.P. (2010) Combinatorial Latency Reactivation for HIV-1 Subtypes and Variants.  J. Virol. 84(12): 5958-5974.   PMCID: PMC2876650

Castanotto, D., and Rossi, J.J. (2009) The promises and pitfalls of RNA-interference-based therapeutics. Nature 457: 426-433.  PMCID: PMC2702667

Sun G, Li H, Rossi JJ. (2009) Sequence context outside the target region influences the effectiveness of miR-223 target sites in the RhoB 3'UTR. Nucl. Acid Res. 38: 239-252.  PMCID: PMC2800228

Castanotto, D., Lingeman, R., Riggs, A.D. and Rossi, J.J. (2009) CRM1 mediates nuclear-cytoplasmic shuttling of mature microRNAs.  Proc. Natl. Acad. Sci. USA 106(51): 21655-21659.  PMCID: PMC2787469

Zhou, J., Swiderski, P., Li, H., Zhang, J., Neff, C.P., Akkina, R., and Rossi, J.J. (2009) Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells. Nucl. Acid. Res. 37: 3094-3109.  PMCID: PMC2685106

Zhou, J., Li, H., Li, S., Zaia, J. and Rossi J.J. (2008) Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy.  Mol. Ther. 16(8): 1481– 489.  PMCID: PMC2727148

Unwalla, H and Rossi J.J. (2008) Tat-regulated Expression of RNA Interference:  Triggers for the Treatment of HIV Infection. Current HIV/AIDS Reports 5(1): 40-43.  PMCID:  PMC2703456
Collingwood, M.A., Rose, S.D., Huang, L., Hillier, C., Amarzguioui, M., Wilger, M.T., Soifer, H.S., Rossi, J.J. and Behlke, M.A. (2008) Chemical Modification Patterns Compatible with High Potency Dicer-Substrate Small Interfering RNAs.  Oligonucleotides 18: 187-199.  PMCID:  PMC2582043

Rossi, J.J. (2008) Expression Strategies for Short Hairpin RNA Interference Triggers. Hum. Gene Ther.  19(4): 313-317.  PMCID:  PMC2702704

Lee, N.-S., Kim, D.H., Alluin, J., Robbins, M., Gu, S., Li, H., Kim, J., Salvaterra, P.M. and Rossi J.J. (2008) Functional and intracellular localization properties of U6 promoter-expressed siRNAs, shRNAs, and chimeric VA1 shRNAs in mammalian cells. RNA 14(9): 1823-1833.  PMCID:  PMC2525953

Kim, D. and Rossi J.J. (2008) RNAi Mechanisms and Applications. BioTechniques 44(5): 613-616. 

Aagaard, L., Zhang, J., von Eije, K.J., Li, Haitang, Saetrom, P., Amarzguioui, M., and Rossi J.J. (2008) Engineering and optimization of the mir-106b cluster for ectopic expression of multiplexed anti-HIV RNAs.  Gene Ther. 15: 1536-1549. PMCID:  PMC3155610

Sano, M., Li, H., Nakanishi, M. and Rossi, J.J. (2008) Expression of Long Anti-HIV1 Hairpin RNAs for the Generation of Multiple siRNAs:  Advantages and Limitations.  Mol. Ther. 16: 170-177.  PMCID: PMC2727148

Rossi, J.J., June, C.H. and Kohn, D.B. (2007) Review - Genetic therapies against HIV.  Nat. Biotech. 25(12): 1-11.

Kim, D., Villeneuve, L., Morris, K. and Rossi, J.J.  (2006) Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells. Nature Struct. & Mol. Biol. 13(9): 793-797.

This is a partial list. Full publications list available upon request. Information on this page may be self-reported and is subject to change at any time. Last updated: 4/13.

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