Zhao C, Sun G, Li S, Lang M-F, Yang S, Li W, and Shi Y. 2010. MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling. Proc. Natl. Acad. Sci. USA 107: 1876-1881.

Sun G, Alzayady K, Stewart R, Ye P, Yang S, Li W, and Shi Y. 2010. Histone demethylase LSD1 regulates neural stem cell proliferation. Mol. Cell. Biol. 30: 1997-2005.

Qu Q, Sun G, Li W, Yang S, Ye P, Zhao C, Yu RT, Gage FH, Evans RM, Shi Y. 2010. Orphan nuclear receptor TLX activates Wnt/β-catenin signaling to stimulate neural stem cell proliferation and self-renewal. Nature Cell Biology 12:31-40 (Leading Article). 

Zhao C, Sun G, Li S, and Shi Y. 2009. A feedback regulatory loop of microRNA-9 and nuclear receptor TLX in neural stem cell fate determination. Nature Structure and Mol. Biol. 16: 365-371.

Qu Q, Shi Y. 2009. Neural stem cells of the developing and adult brains. J. Cell. Physiology 221:5-9.

Shi Y. 2008 Induced pluripotent stem cells, new tools for drug discovery and new hope for stem cell therapies. Current Molecular Pharmacology 2: 15-18.

Li W, Sun G, Yang S, Qu Q, Nakashima K, and Shi Y. 2008. Orphan Nuclear Receptor TLX in Neural Development. Molecular Endocrinology 22: 56-64 (Featured as a cover story).

Shi Y, Sun G, Zhao C, & Stewart R. Stem cell self-renewal. 2008. Critical Reviews in Oncology/Hematology 65: 43-53.

Sun G, Yu RT, Evans RM, and Shi Y. 2007. Orphan Nuclear Receptor TLX Recruits Histone Deacetylases to Repress Transcription and Regulate Neural Stem Cell Proliferation. Proc. Natl. Acad. Sci. USA 104: 15282-15289; Featured in Leading Edge Neurobiology Select, Cell 131: 197.           

Shi Y. 2007. Orphan nuclear receptors in drug discovery. Drug Discovery Today 12: 440-445.

Shi Y. 2006. Orphan nuclear receptors, excellent targets of drug discovery. CCHTS 9: 683-689.

Shi Y, Sun G, and Stewart R. 2006. Nuclear receptors in stem cell biology. Critical Rev. Euk. Gene Exp.16: 171-181.

Jacobs S, Lie DC, DeCicco KL, Shi Y, DeLuca LM, Gage FH, and Evans RM. 2006. Retinoic acid is required early during adult neurogenesis in the dentate gyrus. Proc. Natl. Acad. Sci. USA 103:3902-3907.

Shi Y, Lie DC, Taupin P, Nakashima K, Ray J, Yu RT, Gage FH, and Evans RM. 2004. Expression and function of orphan nuclear receptor TLX in adult neural stem cells. Nature 427: 78-83.

Shi Y, Hon M, Evans RM. 2002. The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling. Proc. Natl. Acad. Sci. USA 99:2613-2618.

Shi Y, Downes M, Xie W, Kao H-Y, Odentlich P, Tsai, C-C, Hon M, and Evans RM. 2001. SHARP, an inducible cofactor that integrates nuclear receptor repression and activation.  Genes & Dev. 15:1140-1151.

Xie W, Radominska-Pandya A., Shi Y, Simon CM, Nelson MC, Ong ES, Waxman DJ, and Evans RM. 2001. An essential role for SXR/PXR in detoxification of cholestatic bile acids. Proc. Natl. Acad. Sci. USA 98:3375-3380.

Shi Y, Doucas V, Miyamoto S, West A, Verma I, and Evans RM. 2000. Cytoplasmic Regulation of GR transcription by a RelA-PKAc dependent mechanism. Proc. Natl. Acad. Sci. USA 97: 11893-11898. (co-first author)

Shi Y, Mosser DD, and Morimoto RI. 1998. Molecular Chaperones as HSF1 Transcriptional Repressors. Genes & Dev.12: 654-666.

Shi Y, Kroeger P, and Morimoto RI. 1995. The Carboxyl-terminal Transactivation Domain of HSF1 is Negatively Regulated and Stress Responsive. Mol. Cell. Biol. 15: 4309-4318.

This is a partial list. Full publications list available upon request. Information on this page may be self-reported and is subject to change at any time. Last updated: 06/10.