Li, Y., Reddy, M.A., Miao, F., Shanmugam, N., Yee, J.K., Hawkins, D., Ren, B. & Natarajan, R. “Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-B dependent inflammatory genes: Relevance to diabetes and inflammation” J. Biol. Chem. (In press).

Arumugam, P.I., Scholes, J., Perelman, N., Xia, P., Yee, J.K. & Malik, P., “Improved human beta-globin expression from self-inactivating lentiviral vectors carrying the chicken hypersensitive site-4 (cHS4) insulator element” Mol. Ther. 15, 1863-1871 (2007).

Lo, H.-L., Chang, T., Yam, P., Marcovecchio, P.M., Li, S., Zaia, J.A. & Yee, J.K., “Inhibition of HIV-1 replication with designed miRNA expressed from RNA polymerase II promoters” Gene Ther. 14, 1503-1512 (2007).

Anderson, J., Li, M.J., Palmer, B., Remling, L., Li, S., Yam, P., Yee, J.K., Rossi, J., Zaia, J. & Akkina, R. “In vivo derivation of HIV-1 resistant transgenic T cells by lentiviral vector transduction of a triple combination of anti-HIV genes anti-CCR5 ribozyme, tat-rev siRNA and a TAR decoy” Mol. Ther. 15, 1182-1188 (2007).

Guo, C., Tommasi, S., Liu, L., Yee, J.K., Dammann, R. & Pfeifer, G. “The RASSF1A tumor suppressor protein is a component of a mammalian complex analogous to the Drosophila Hippo/Salvador/Lats tumor suppressor network” Curr. Biol. 17:700-705 (2007).

Modi, H., McDonald, T., Chu, S., Yee, J.K., Forman, S.J. & Bhatia, R. “Role of BCR/ABL gene expression levels in determining the phenotype and imatinib sensitivity of transformed human hematopoietic cells” Blood 109:5411-5421 (2007).

Hall, S.L., Lau, K.H. W., Chen, S.T., Felt, J.C., Gridley, D.S., Yee, J.K. & Baylink, D.J. “An improved mouse Sca-1+ cell-based bone marrow transplantation model for use in gene and cell based therapeutic studies” Acta Haematologica 117:24-33 (2007).

Gu, S., Ji, J., Kim J.D., Yee, J.K. & Rossi, J.J. “Inhibition of infectious human immunodeficiency virus type 1 virions via lentiviral vector encoded short antisense RNAs” Oligonucleotides 16: 287-295 (2006).

Luo, F., Yee, J.K., Huang, S.H., Wu, L.T. & Jong, A.Y. “Downregulation of human CDC6 protein using a lentivirus RNA interference expression vector” Methods in Mol. Biol. 342:285-292 (2006).

Yee, J.K. “Generation of VSV-G pseudotyped retroviral vectors” pp107-117 in Gene transfer: delivery and expression of DNA and RNA, a laboratory manual, Friedmann, T. & Rossi, J.J., eds., Cold Spring Harbor Laboratory Press, New York, (2006).

Yam, P., Jensen, M., Akkina, R., Anderson, J., Villacres, M.C., Wu, J., Zaia, J. & Yee, J.K. “Ex vivo selection and expansion of cells based on expression of a mutated inosine monophosphate dehydrogenase 2 after HIV vector-transduction: Effect on lymphocytes, monocytes and CD34+ stem cells. HIV vector-transduced T lymphocytes expressing a mutant inosine monophosphate dehydrogenase 2” Mol. Ther. 14:236-244 (2006).

Malik, P., Arumugam, P.I., Yee, J.K. & Puthenveetil, G. “Successful correction of the human Cooley’s anemia beta-thalassemia major phenotype using a lentiviral vector flanked by the chicken hypersensitive site 4 chromatin insulator” Ann. NY Acad. Sci. 1054:238-249 (2005).

Li, M-J., Kim, J., Li, S., Zaia, J., Yee, J.K., Anderson, J., Akkina, R., & Rossi, J.J. “Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy” Mol. Ther. 12:900-909 (2005).

Puthenveetil, G., Scholes, J., Qureshi, N., Carbonell, D., Xia, P., Zheng, L., Hiti, A., Li, S., Yu, Y., Yee, J.K. & Malik, P. “Successful correction of human beta thalassemia major using a self-inactivating lentiviral vector carrying a chromatin insulator” Blood 104: 3429-3436 (2004).

Ramaraj, P., Singh, H., Niu, N., Holtz, M., Yee, J.K. & Bhatia, R. “Effect of mutational inactivation of tyrosine kinase activity on BCR/ABL induced abnormalities in cell growth and adhesion in human hematopoietic progenitors” Cancer Research 64: 5322-5331 (2004).

Kowolik, C.M., Liang, S., Yu, Y. & Yee, J.K. “Cre-mediated reversible immortalization of human renal proximal tubular epithelial cells" Oncogene 23: 5950-5957 (2004).

Li, M. -J., McMahon, R., Snyder, D.S., Yee, J.K. & Rossi, J.J. “Specific killing of Ph+ chronic myeloid leukemia cells by a lentiviral vector delivered anti-bcr/abl small hairpin RNA” Oligonucleotides 13: 401-409 (2003).

Li, M. -J., Bauer, G., Michienzi, A., Yee, J.K., Lee, N. -S., Kim, J., Li, S., Castanotto, D., Zaia, J. & Rossi, J.J. “Inhibition of HIV-1 infection by lentiviral vectors expressing pol III-promoted anti-HIV RNAs” Mol. Ther. 8:196-206 (2003).

Kowolik, C.M., Yam, P., Yu, Y. & Yee, J.K. “HIV vector production mediated by Rev protein transduction” Mol. Ther. 8:324-331 (2003).

Kowolik, C.M. & Yee, J.K. “Preferential transduction of human hepatocytes with lentiviral vectors pseudotyped by sendai virus F protein” Mol. Ther. 5:762-769 (2002).

Yam, P.Y.Y., Li, S., Wu, J., Hu, J., Zaia, J.A. & Yee, J.K. “Design of HIV vectors for efficient gene delivery into human hematopoietic cells” Mol. Ther. 5:479-484 (2002).

Yee, J. -K. & Zaia, J.A “Prospects for gene therapy using HIV-based vectors” Somat. Cell. Mol. Genet. 26: 159-174 (2001).

Peng, H., Chen, S. -T., Wergedal, J.E., Polo, J.M., Yee, J.K., Lau, K. -H.W. & Baylink, D.J. “Development of an MFG-based vector system for secretion of high levels of functionally active human BMP4” Mol. Ther. 4: 95-104 (2001).

Kowolik, C.M., Hu, J., & Yee, J.K. "Locus control region of the human CD2 gene in a lentivirus vector confers position-independent transgene expression." J. Virol. 75:10 4641- 4648 (2001).

Chow, W.A., Fang, J.J., & Yee, J.K. "The IFN regulatory factor family participates in regulation of fas ligand gene expression in T cells." J. Immunol. 164:7 3512- 3518 (2000).

Johnston, J.C., Gasmi, M., Yee, J.K., Jolly, D.J., Elder, J.H. & Sauter, S.L. “Minimal requirements for efficient transduction of dividing and nondividing cells by feline immunodeficiency virus vectors.” J. Virol. 73, 4991-5000 (1999).

Gasmi, M., Glynn, J., Jin, M.J., Jolly, D.J., Yee, J.K. & Chen, S.T. “Requirements for efficient production and transduction of human immuodeficiency virus type 1-based vectors.” J. Virol. 73, 1828-1834 (1999).

Yee, J. -K. “Retroviral vectors” in The Development of Human Gene Therapy, Friedmann, T., ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, Chapter 2, (1998).

Yam, P.Y.Y., Yee, J.K., Ito, J.I., Sniecinski, I., Doroshow, J.H., Forman, S.J. & Zaia, J.A. “Amphotropic and pseudotyped VSV-G retroviral transduction of human CD34+ peripheral blood progenitor cells (PBPC): Comparison in PBPC from adult donors with HIV-1 infection or with cancer.” Exp. Hematol. 26, 962-968 (1998).

Chen, S.T., Iida, A., Guo, L., Friedmann, T. & Yee, J.K. "Generation of packaging cell lines for VSV-G pseudotyped retroviral vectors using a modified tetracycline-inducible system." Proc. Natl. Acad. Sci. USA 93,10057-10062 (1996).

Iida, A., Chen, S.T., Friedmann, T. & Yee, J.K. "Inducible gene expression by retrovirus-mediated transfer of a modified tetracycline-regulated system." J. Virol. 70, 6054- 6059 (1996).

Friedmann, T. and Yee, J.K. "Pseudotyped retroviral vectors for studies of human gene therapy” Nature Medicine 1, 275-277 (1995).

Yee, J.K., Miyanohara, M., LaPorte, P., Bouic, K., Burns, J.C. and Friedmann, T. "Generation of high titer, pantropic retroviral vectors: Efficient gene transfer into hepatocytes." Proc. Natl. Acad. Sci. USA 91, 9564-9568 (1994).

Lin, S., Gaiano, N., Culp, P., Burns, J.C. Friedmann, T., Yee, J.K. and Hopkins, N. "Integration and germ line transmission of a pseudotyped retroviral vector in zebrafish." Science 265, 666-669 (1994).

Yee, J. -K., Friedmann, T. and Burns, J.C. "Generation of high-titer pseudotyped retroviral vectors with very broad host range." Methods in Cell Biology, 43, 99-112 (1994).

Chen, S. -T., La Porte, P. and Yee, J. -K. "Mutational analysis of hepatitis B virus enhancer 2." Virology 196, 652-659 (1993).

Burns, J.C., Friedmann, T., Driever, W., Burrascano, M. and Yee, J.K. "VSV-G pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells." Proc. Natl. Acad. Sci. USA 90, 8033-8037 (1993).

Chen, S. -T., Su, H. and Yee, J. -K. "Adenovirus E1A-mediated transcriptional repression of hepatitis B virus enhancer activity." J. Virol. 66, 7452-7460 (1992).

Su, H. and Yee, J. -K. "Regulation of hepatitis B virus gene expression by its two enhancers." Proc. Natl. Acad. Sci. USA 89, 2708-2712 (1992).

Emi, N., Friedmann, T. and Yee, J. -K. "Pseudotype formation of murine leukemia virus with the G protein of vesicular stomatitis virus." J. Virol. 65, 1202-1207 (1991).

Yee, J. -K. "A liver-specific enhancer in the core promoter region of human Hepatitis B virus." Science, 246, 658-661 (1989).

Huang, H. -J.S., Yee, J. -K., Shew, J. -Y., Chen, P. -L., Bookstein, R., Friedmann, T., Lee, E.Y.-H.P. and Lee, W. -H. "Suppression of the neoplastic phenotype by replacement of the human retinoblastoma gene product in retinoblastoma and osteosarcoma Cells." Science 242, 1553-1556 (1988).

Yee, J. -K., Moores, J.C., Jolly, D.J., Wolff, J.A., Respess, J.G. and Friedmann, T. "Gene expression from transcriptionally disabled retroviral vectors." Proc. Natl. Acad. Sci. USA 84, 5197-5201 (1987).

Gruber, H.E., Finley, K.D., Hershberg, R.M., Katzman, S.S., Laikind, P.K., Seegmiller, J.E., Friedmann, T., Yee, J. -K. and Jolly, D.J. "Retroviral vector-mediated gene transfer into human hematopoietic progenitor cells." Science 230, 1057- 1061 (1985).


This is a partial list. Full publications list available upon request. Information on this page may be self-reported and is subject to change at any time. Last updated: 10/08.