Innovative Partnerships: U.S.-China Stem Cell and Cancer Discoveries

Presented by Beckman Research Institute of City of Hope and the Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, and the Consulate General of the People’s Republic of China Los Angeles

October 4 and 5, 2012 
Argyros Auditorium, City of Hope, Duarte, CA

October 4, 2012 – Argyros Auditorium

8:00 a.m.       
Registration  
 
8:30 a.m.       
Welcome  
Michael A. Friedman, M.D., Chief Executive Officer, City of Hope
Shaofang Qiu, Consul General of the People’s Republic of China

8:45 a.m.       
Overview  
Richard Jove, Ph.D., Emeritus Director, Beckman Research Institute,
Professor, Molecular Medicine, City of Hope 
Duanqing Pei, Ph.D., Director General, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
  
Session I Reprogramming and Pluripotent Stem Cells
Session Chairs:
Hongkui Deng, Ph.D., Peking University
Clive Svendsen, Ph.D., Cedars Sinai Medical Center

9:00 a.m. 
Clive Svendsen, Ph.D., Cedars Sinai Medical Center
Using induced pluripotent stem cells to model and treat human disease
  
9:30 a.m. 
Duanqing Pei, Ph.D., Guangzhou Institutes of Biomedicine and Health
Reprogramming the somatic cell fate to pluripotency by vitamin c and histone modification enzymes

10:00 a.m. 
BREAK

10:30 a.m. 
Robert Blelloch, M.D., Ph.D., University of California, San Francisco
MicroRNA-regulated networks in the maintenance of mammalian pluripotency

11:00 a.m.  
Qi Zhou, Ph.D., Institute of Zoology, Chinese Academy of Sciences
The progress of stem cell research and its potential application in clinical trails

11:30 a.m. 
Zhong Zhong, Ph.D., GlaxoSmithKline in Shanghai  
Human disease modelling with iPS and ESC

12:00 noon 
Yinxiong Li, M.D., Ph.D., Guangzhou Institutes of Biomedicine and Health  
Adult hepatic progenitor cell and injured liver regeneration in fish models

12:30 p.m.  
LUNCH

Session II: Differentiation and Tissue Stem Cells
Session Chairs: 
Ellen Feigal, M.D., California Institute for Regenerative Medicine
Yanhong Shi, Ph.D., City of Hope

1:30 p.m.
Cun-Yun Wang, D.D.S., Ph.D., University of California, Los Angeles
Epigenetic Control of Human Mesenchymal Stem Cell Fate

2:00 p.m. 
Hongkui Deng, Ph.D., Peking University
Generating β Cells from pluripotent stem cells

2:30 p.m. 
Su-Chun Zhang, Ph.D., University of Wisconsin
Human stem cells for therapeutic development

3:00 p.m. 
Ricardo Dolmetsch, Ph.D. Stanford University
Using stem cells to study autism spectrum disorders

3:30 p.m. 
BREAK

3:45 p.m. 
Yanhong Shi, Ph.D., City of Hope
Stem cells in the nervous system

4:15 p.m. 
Ying Li, Ph.D., City University of Hong Kong
Vagal afferent neuronal plasticity: Implication in the emesis related to chemotherapy

4:45 p.m. 
Zhigang He, Ph.D., Harvard University
Reprogramming neuronal regenerative ability

5:15 p.m. 
Bennett Novitch, Ph.D., UCLA
Building and breaking down the neuroepithelial stem and progenitor cell niche
 
October 5, 2012 – Argyros Auditorium
 
Special Session: Innovative Partnerships
Session Chairs:
Duanqing Pei, Ph.D., Guangzhou Institutes of Biomedicine and Health
Emily Wang, Ph.D., City of Hope

8:30 a.m.       
Ellen Feigal, M.D., and Michael P. Yaffe, Ph.D.,
California Institute for Regenerative Medicine
Advancing Stem Cell Science Towards Translation: CIRM and the Role of International Collaborations

9:00 a.m. 
Jonathan Oliner, M.D., Ph.D., Amgen
Amgen Oncology Research

Session III: Cancer Stem Cells
Session Chairs:
Hua Yu, Ph.D., City of Hope
Tao Cheng, Ph.D., Chinese Academy of Medical Sciences

9:15 a.m. 
Ravi Bhatia, M.D., City of Hope
Biology and Targeting of Leukemia Stem cells

9:45 a.m.
Yingjie Wang, Ph.D., Zhejiang University
The interplay between Akt and Oct4 promotes the self-renewal and survival of embryonal carcinoma cells

10:15a.m. 
BREAK

10:30 a.m. 
Jian-hong Zhu, M.D., Ph.D., Fudan University
Translational path for neural stem cells to the clinic

11:00 a.m.  
Tao Cheng, Ph.D., Chinese Academy of Medical Sciences
Hematopoietic stem cells in response to stress, damage or disease

11:30 a.m. 
Owen Witte, Ph.D, University of California, Los Angeles    
Stem cells in prostate cancer initiation and progression

12:00 noon
LUNCH

Session IV: Cancer Mechanism and Therapeutics
Session Chairs: 
Linda Malkas, Ph.D, City of Hope
Hui Li, Ph.D, Tianjin Cancer Research Institute

1:00 p.m. 
Hua Yu, Ph.D., City of Hope
STAT3 in cancer and cancer stem cells

1:30 p.m. 
Kun-Liang Guan, Ph.D, University of California, San Diego
The Hippo-YAP pathway in organ size control and tumorigenesis

2:00 p.m. 
Tyler Curiel, M.D., University of Texas
Novel approaches to cancer immunotherapy

2:30 p.m. 
BREAK

2:45 p.m. 
Stephen Baylin, M.D.,  Johns Hopkins University
DNA methylation and the cancer epigenome – implications for the cancer “stem cell” concept

3:15 p.m. 
Fuchou Tang, Ph.D., Peking University
Deciphering gene expression network of mammalian early embryos and embryonic stem cells at single cell and single base resolution

3:45 p.m. 
Guoguang Ying, Ph.D., Tianjin Cancer Research Institute
Trafficking towards cancer

4:15 p.m. 
Binghui Shen, Ph.D., City of Hope
Closing Remarks