Red wine has long been associated with longevity, thanks to a compound it contains called resveratrol. Scientists say that this compound may extend a person’s life span because it helps control the body’s response to environmental stresses that cause DNA damage to cells.
Now, through the support of generous donors like you, City of Hope scientists are building on that knowledge to push the benefits of resveratrol to new levels in the fight against cancer.
A recent study conducted at City of Hope shows that when resveratrol is combined with a cancer-fighting drug called an HDAC inhibitor, the effects of the resveratrol are even greater. The combination of these two agents holds the promise of a more effective treatment for lymphoma at City of Hope.
The study was led by Anna A.G. Scuto, Ph.D., assistant research professor of molecular medicine, with the guidance of senior author Richard Jove, Ph.D., who holds the Morgan and Helen Chu Director’s Chair and is director of the Beckman Research Institute of City of Hope.
Dr. Scuto and her team already knew that resveratrol and HDAC inhibitors had anti-cancer effects against lymphoma when used separately.
But in their study, the team found that these compounds can control the growth of tumors and encourage cancer cell death even more efficiently when they are used together—a discovery that could lead to a new combination therapy to fight lymphoma and save even more lives.
This breakthrough is an important step forward. Now, we need your help to transform discoveries like these into powerful treatments for our patients. So please use the attached reply form to send the most generous gift you can. Thank you so much!