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Biostatistics Core Facility

Director: Jeffrey Longmate, Ph.D.
Co-Director: David Smith, Ph.D.

The Biostatistics Core facility draws upon a group of statisticians who collaborate in basic, translational, clinical and population research in the City of Hope Comprehensive Cancer Center. The Core is supported by City of Hope’s NCI-funded Cancer Center Support Grant (CCSG), with additional institutional support.  Its services are available to all City of Hope and Beckman researchers.
 
Areas of expertise include:  Basic science:  statistical methods for assays and bioassays, animal models, genomics (RNA-seq, CHIP-seq, microarray, rRNA microbial classification), mutation spectra, experimental genetics; Translational science:  animal models, xenografts, cell migration, statistics for toxicology, pharmacokinetic modeling; Clinical Science:  clinical trials, diagnostics, biomarkers, retrospective clinical studies, clinical epidemiology; Population Science: Epidemiology, genetic epidemiology; General:  numerical and graphical data summary, statistical inference, and prediction models.
 
Research Roles: Core members can help with study design, grant proposals, clinical protocols, data analysis, and manuscripts.

Services

Collaboration in research intended for publication is our main activity.  Contact any core statistician, or contact the director for an introduction (email: #biostat_core).
 
Consulting is available to advise investigators on statistical issues in research, or to explore possible collaboration.  This is often simply a collegial interaction, but investigators may contact the director (email: #biostat_core) for an introduction to a statistician.  Consulting generally consists of one or two meetings, and it’s always free.  Early contact about research planning is always welcomed.
 
Case finding: The core can provide HIPAA-compliant identification of patients with stored tissue samples or other clinical and disease characteristics.  (email: #case_finding; phone ext. 32002 or 61444)
 
Statistical Computing is provided in conjunction with collaboration.  The core does not provide user-directed computing, and does not operate a help desk for statistical software.
 
Data extraction from various COH and public databases is provided in conjunction with collaboration, but is not provided as a separate service.
 
To access services or to use the facility, please contact us at 626-256-HOPE (4673), ext. 61444 or via email (#biostat_core or jlongmate@coh.org).
 
Research reported in this publication included work performed in the Biostatistics Core supported by the National Cancer Institute of the National Institutes of Health under award number P30CA33572. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
 

Abstract for Grants

Note:  Proposals including a statistician as a collaborator will ordinarily include a biosketch, and possibly a letter of collaboration.  For proposals in which a statistician has a small, defined role, funding for core support may be included as an expense, in which case you may wish to contact the collaborating statistician or the director for a letter of support.  The following generic statement is provided as a resource, but please contact the Biostatistics Core if you use it.
 
The Biostatistics Core is a shared resource of the City of Hope Comprehensive Cancer Center.  It draws upon 10 doctoral-level statisticians and 6 staff statisticians.  Members of the Biostatistics Core collaborate in basic, translational, clinical and population research, and its services are available to all City of Hope researchers.  Research areas supported include: bioassay, animal models, genomics, genetics, mutation, toxicology, pharmacokinetics, diagnostics, biomarkers, clinical trials, clinical epidemiology; population epidemiology, genetic epidemiology.  In general, the core can provide standard and principled approaches to numerical and graphical data summary, statistical inference, modeling, and prediction. Core members help with study design, grant proposals, clinical protocols, data analysis, and manuscripts.  Statistical software includes SAS, R, StatXact, EaST, and NQuery Advisor.  A linux cluster is available for computationally intensive projects, and COH has excellent network and IT support.
 

Using the Facility

The core encourages collaboration, so investigators are free to contact faculty statisticians directly. You can request an introduction or consulting appointment by phone (ext 61444) or email (#biostat_core).

Any publication involving the use of core services should arrange for submission of the publication to PubMed Central, in compliance with the NIH Public Access Policy, and should include the following acknowledgement:
 
Research reported in this publication included work performed in the Biostatistics Core supported by the National Cancer Institute of the National Institutes of Health under award number P30CA33572. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
 
It is also generally accepted practice that a collaborating statistician from the core will be included in the authorship list if the research is presented in a public forum or published. Authorship is unrelated to funding.

Pricing

Funding core effort:
 
Consulting refers to one-on-one meetings with Core statisticians to discuss the statistical approaches necessary for the research. Consulting is free, but intended primarily for advice and initial planning discussions.
 
Collaborative projects should fund a statistician’s effort in one of the following ways:
 
Grants:  Include appropriate statistician support in the personnel budget.  
Contracts:  Include appropriate statistician effort in the contract.
Clinical trials: Include appropriate statistician effort in the clinical trials finance budget.
Portfolio studies are those for which a department or investigator has arranged for statistical support from specific core personnel, similar to a grant budget.
Other Studies generally require that statistician effort is supported by the investigator via core charges.
Analysis of Data for Publication – (e.g. a novel or unanticipated statistical need) may be left to the statistician’s discretion and availability.
 
Case finding for Letters of Intent (LOIs) is a free service.  Investigators may use iCode for self-service. Case finding for all other uses may be charged at the published core rates.

Other activities: Occasionally, the Biostatistics Core is asked to assist with data extraction or similar activities that are not a core service, not research, or not collaborative.  If such a request is accepted, it will be billed at full cost-recovery (external) rates. 
 
Hourly Charge Rates:
  CCSG Members Internal Users External Users
Staff Biostatisticians $45.00 $50.00 $89.00
PhD/RSO Statisicians $67.50 $75.00 $136.00

 
 

Biostatistics Core Directors

Jeffrey Longmate, Ph.D.
Director
626-256-HOPE (4673), 62478
jlongmate@coh.org

David Smith, Ph.D.
Co-Director
626-256-HOPE (4673)
dsmith02@coh.org
 
Location
City of Hope and Beckman Research Institute
1500 East Duarte Road
Duarte, CA  91010-3000
 
Information Sciences Building (#171)
Phone:  626-256-HOPE (4673), Ext. 61444
Fax:  626-471-7106 or 626-301-8802
 

Biostatistics Core Directors

Biostatistics Core Facility

Biostatistics Core Facility

Director: Jeffrey Longmate, Ph.D.
Co-Director: David Smith, Ph.D.

The Biostatistics Core facility draws upon a group of statisticians who collaborate in basic, translational, clinical and population research in the City of Hope Comprehensive Cancer Center. The Core is supported by City of Hope’s NCI-funded Cancer Center Support Grant (CCSG), with additional institutional support.  Its services are available to all City of Hope and Beckman researchers.
 
Areas of expertise include:  Basic science:  statistical methods for assays and bioassays, animal models, genomics (RNA-seq, CHIP-seq, microarray, rRNA microbial classification), mutation spectra, experimental genetics; Translational science:  animal models, xenografts, cell migration, statistics for toxicology, pharmacokinetic modeling; Clinical Science:  clinical trials, diagnostics, biomarkers, retrospective clinical studies, clinical epidemiology; Population Science: Epidemiology, genetic epidemiology; General:  numerical and graphical data summary, statistical inference, and prediction models.
 
Research Roles: Core members can help with study design, grant proposals, clinical protocols, data analysis, and manuscripts.

Services

Collaboration in research intended for publication is our main activity.  Contact any core statistician, or contact the director for an introduction (email: #biostat_core).
 
Consulting is available to advise investigators on statistical issues in research, or to explore possible collaboration.  This is often simply a collegial interaction, but investigators may contact the director (email: #biostat_core) for an introduction to a statistician.  Consulting generally consists of one or two meetings, and it’s always free.  Early contact about research planning is always welcomed.
 
Case finding: The core can provide HIPAA-compliant identification of patients with stored tissue samples or other clinical and disease characteristics.  (email: #case_finding; phone ext. 32002 or 61444)
 
Statistical Computing is provided in conjunction with collaboration.  The core does not provide user-directed computing, and does not operate a help desk for statistical software.
 
Data extraction from various COH and public databases is provided in conjunction with collaboration, but is not provided as a separate service.
 
To access services or to use the facility, please contact us at 626-256-HOPE (4673), ext. 61444 or via email (#biostat_core or jlongmate@coh.org).
 
Research reported in this publication included work performed in the Biostatistics Core supported by the National Cancer Institute of the National Institutes of Health under award number P30CA33572. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
 

Abstract for Grants

Abstract for Grants

Note:  Proposals including a statistician as a collaborator will ordinarily include a biosketch, and possibly a letter of collaboration.  For proposals in which a statistician has a small, defined role, funding for core support may be included as an expense, in which case you may wish to contact the collaborating statistician or the director for a letter of support.  The following generic statement is provided as a resource, but please contact the Biostatistics Core if you use it.
 
The Biostatistics Core is a shared resource of the City of Hope Comprehensive Cancer Center.  It draws upon 10 doctoral-level statisticians and 6 staff statisticians.  Members of the Biostatistics Core collaborate in basic, translational, clinical and population research, and its services are available to all City of Hope researchers.  Research areas supported include: bioassay, animal models, genomics, genetics, mutation, toxicology, pharmacokinetics, diagnostics, biomarkers, clinical trials, clinical epidemiology; population epidemiology, genetic epidemiology.  In general, the core can provide standard and principled approaches to numerical and graphical data summary, statistical inference, modeling, and prediction. Core members help with study design, grant proposals, clinical protocols, data analysis, and manuscripts.  Statistical software includes SAS, R, StatXact, EaST, and NQuery Advisor.  A linux cluster is available for computationally intensive projects, and COH has excellent network and IT support.
 

Using the Facility

Using the Facility

The core encourages collaboration, so investigators are free to contact faculty statisticians directly. You can request an introduction or consulting appointment by phone (ext 61444) or email (#biostat_core).

Any publication involving the use of core services should arrange for submission of the publication to PubMed Central, in compliance with the NIH Public Access Policy, and should include the following acknowledgement:
 
Research reported in this publication included work performed in the Biostatistics Core supported by the National Cancer Institute of the National Institutes of Health under award number P30CA33572. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
 
It is also generally accepted practice that a collaborating statistician from the core will be included in the authorship list if the research is presented in a public forum or published. Authorship is unrelated to funding.

Pricing

Pricing

Funding core effort:
 
Consulting refers to one-on-one meetings with Core statisticians to discuss the statistical approaches necessary for the research. Consulting is free, but intended primarily for advice and initial planning discussions.
 
Collaborative projects should fund a statistician’s effort in one of the following ways:
 
Grants:  Include appropriate statistician support in the personnel budget.  
Contracts:  Include appropriate statistician effort in the contract.
Clinical trials: Include appropriate statistician effort in the clinical trials finance budget.
Portfolio studies are those for which a department or investigator has arranged for statistical support from specific core personnel, similar to a grant budget.
Other Studies generally require that statistician effort is supported by the investigator via core charges.
Analysis of Data for Publication – (e.g. a novel or unanticipated statistical need) may be left to the statistician’s discretion and availability.
 
Case finding for Letters of Intent (LOIs) is a free service.  Investigators may use iCode for self-service. Case finding for all other uses may be charged at the published core rates.

Other activities: Occasionally, the Biostatistics Core is asked to assist with data extraction or similar activities that are not a core service, not research, or not collaborative.  If such a request is accepted, it will be billed at full cost-recovery (external) rates. 
 
Hourly Charge Rates:
  CCSG Members Internal Users External Users
Staff Biostatisticians $45.00 $50.00 $89.00
PhD/RSO Statisicians $67.50 $75.00 $136.00

 
 

Contact Us

Biostatistics Core Directors

Jeffrey Longmate, Ph.D.
Director
626-256-HOPE (4673), 62478
jlongmate@coh.org

David Smith, Ph.D.
Co-Director
626-256-HOPE (4673)
dsmith02@coh.org
 
Location
City of Hope and Beckman Research Institute
1500 East Duarte Road
Duarte, CA  91010-3000
 
Information Sciences Building (#171)
Phone:  626-256-HOPE (4673), Ext. 61444
Fax:  626-471-7106 or 626-301-8802
 

Biostatistics Core Facility Directors

Biostatistics Core Directors

Research Shared Services

City of Hope embodies the spirit of scientific collaboration by sharing services and core facilities with colleagues here and around the world.
 

Recognized nationwide for its innovative biomedical research, City of Hope's Beckman Research Institute is home to some of the most tenacious and creative minds in science.
City of Hope is one of only 41 Comprehensive Cancer Centers in the country, the highest designation awarded by the National Cancer Institute to institutions that lead the way in cancer research, treatment, prevention and professional education.
Learn more about City of Hope's institutional distinctions, breakthrough innovations and collaborations.
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