Colorectal cancer is the fourth most common form of cancer diagnosed in the U.S., with more than 132,000 new cases each year.

If you've been diagnosed with cancer of the colon or rectum, talk to us. It's important to learn about your options and take action right away. Survival rates for colorectal cancer have improved dramatically, especially when the disease is caught early. Our world-class team of specialists can answer your questions, address your concerns, and deliver a personalized treatment plan with the most innovative, cutting-edge therapies available anywhere.

At City of Hope, we are committed to treating the whole person, body and soul. We have an unmatched reputation for coordinated, compassionate care. We bring together a broad array of colorectal cancer expertise from multiple disciplines, all under one roof:

  • State-of-the-art screenings and diagnostic tools including colonoscopy and stool DNA testing
  • Minimally-invasive, robotically-assisted surgery for fewer complications and faster recovery
  • Surgical specialists dedicated to preserving quality of life, reducing the need for colostomy
  • Ultra-precise radiation therapy to target tumors and preserve healthy tissue
  • Targeted drugs and drug combinations for greater effectiveness and fewer side effects
  • Pioneering drug research and clinical trials

Plus, your supportive care continues long after treatment is complete. Our specialists will help you adjust to post-treatment diet and lifestyle changes, and our unique family and survivorship programs will assist your loved ones.

Learn more about colorectal cancer.

Request an Appointment

If you have been diagnosed with colorectal cancer, looking for a second opinion consultation about your treatment or would like to get colorectal cancer screening, request an appointment online or contact us at 800-826-HOPE. Please visit Making Your First Appointment for more information.

Care Team

City of Hope’s renowned physicians and researchers utilize the latest in technology and innovation to treat cancer, coupled with our enduring belief in providing unparalleled compassionate care.

Joe Chao, M.D.

Clinical Specialties:

  • Medical Oncology
Yi-Jen Chen, M.D., Ph.D.

Clinical Specialties:

  • Radiation Oncology
Vincent Chung, M.D., F.A.C.P.

Clinical Specialties:

  • Medical Oncology
Donald S. David, M.D., F.A.C.G.

Clinical Specialties:

  • Gastroenterology
Marwan G. Fakih, M.D.

Clinical Specialties:

  • Medical Oncology
Jonathan Kessler, M.D.

Clinical Specialties:

  • Diagnostic Radiology
  • Interventional Radiology
Lily Lai, M.D., F.A.C.S.

Clinical Specialties:

  • Surgical Oncology
Dean W. Lim, M.D.

Clinical Specialties:

  • Medical Oncology
James L Lin, M.D.

Clinical Specialties:

  • Gastroenterology
Kurt Allan Melstrom, M.D.

Clinical Specialties:

  • Colon and Rectal Surgery
Sentovich-Stephen M.
Stephen M. Sentovich, M.D., MBA

Clinical Specialties:

  • Colon and Rectal Surgery

Success Stories

Anne Bourque Success Story Image
Anne, colorectal cancer survivor

Cancer-free since 2002, Anne recently celebrated her 60th birthday with family and continues to bring hope and inspiration for City of Hope patients today.

Tests & Treatments

Every patient is different, with different needs. With one of the most renowned colorectal cancer programs in America, City of Hope treats you as a valued individual. Our entire team works together to bring you precise, state-of-the-art surgical, drug therapy, radiation and other options that will deliver the best outcome for you. We support you every step of the way, both during treatment and long after, helping you and your loved ones manage your recovery and boost your quality of life.

Learn more about screening and treatment options for colorectal cancer, including surgery / robotically-assisted surgery, radiation, chemotherapy and targeted therapy.

Clinical Trials

At City of Hope, we offer access to numerous clinical trials aimed at improving survival rates and enhancing quality of life. Many of these new therapies are not always available elsewhere. Our latest research covers many areas including new drug combinations that prevent colorectal cancer recurrence, profiling of cancer tissue at the molecular level to determine genetic abnormalities, and blocking a specific protein known to cause a form of the disease.

Browse through some of our clinical trials and research projects listed below:


When you come to City of Hope, you automatically gain access to an unparalleled array of support services to help you and your family cope with each challenge in your colorectal cancer journey. We can help with all of these concerns, and more:

  • Managing pain, fatigue, nausea
  • Adjusting to new diet and lifestyle habits
  • Your emotional, social and spiritual well-being
  • Staying healthy and active
  • Healthy cooking and eating
  • Healing arts
  • Caregiver skills
  • Dealing with family stress
  • Navigating the health care system

Learn more about these resources at our Living with Cancer or Supportive Care Medicine sites.

Additional Resources:

I’ve Just Been Told I Have Colorectal Cancer
Frequently Asked Questions About Colorectal Cancer
Questions to Ask about Treatment for Colorectal Cancer
Do What You Can to Ease Side Effects of Treatment and Symptoms of Colorectal Cancer
How Surgery for Colorectal Cancer Affects What You Can Eat
How Surgery for Colorectal Cancer Affects Your Bowel Function
Living with a Colostomy: Tips for Maintenance and Daily Living

Support the Colorectal Cancer Program

It takes the help of a lot of caring people to make hope a reality for our patients. City of Hope was founded by individuals' philanthropic efforts more than 100 years ago. Their efforts − and those of our supporters today − have built the foundation for the care we provide and the research we conduct. It enables us to strive for new breakthroughs and better therapies − helping more people enjoy longer, better lives.

For more information on supporting this specific program, please contact us below.

Joe Komsky
Senior Development Officer
Phone: 626-218-6291
Email: [email protected]

Or, you can make a gift to support all the research at City of Hope by donating online.


An Expert's Voice

City of Hope experts cover prevention, screening, treatment and other cancer topics on City of Hope’s Breakthrough’s blog.

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