An estimated 20 million, or approximately 7 percent, of Americans have diabetes, and many more are at risk for developing the disease. Diabetes is a disease in which the body does not produce or properly use insulin, a hormone necessary for converting dietary sugar and starches into energy. 

The major types of diabetes include:

  • Type 1 diabetes: formerly known as juvenile-onset or insulin-dependent diabetes, this type is an autoimmune disease in which the body's own immune system slowly destroys insulin-producing islet cells in the pancreas.
  • Type 2 diabetes: formerly known as adult-onset diabetes or insulin independent diabetes, in this type the insulin does not work effectively and is not sufficient to keep the blood sugar level normal. Thus the body's cells are unable to properly use glucose.
  • Maturity-onset Diabetes of the Young (MODY): This form of diabetes is inherited and can vary in severity. Often, MODY resembles a very mild version of type 1 diabetes with continued partial insulin production and normal insulin sensitivity.
  • Gestational diabetes: This type of diabetes develops during pregnancy in women who have never been diagnosed with diabetes, with symptoms usually occur during the second or third trimester.

At City of Hope, we are committed to treating the whole person, body and soul. We have an unmatched reputation for coordinated, compassionate care, and our Diabetes & Metabolism Research Institute brings together a broad array of diabetes expertise from multiple disciplines, all under one roof:

  • Diabetologists and certified educators who can help patients keep their blood sugar under control, reducing likelihood of high- or low- blood sugar episodes and long-term complications
  • Islet cell transplantation program for eligible type 1 diabetics
  • Innovative clinical trials, such as an "artificial pancreas" that combines glucose monitoring and insulin pump technologies, reducing the need for constant monitoring and insulin administration

Plus, your supportive care continues long after treatment is complete. Our specialists will help you adjust to post-treatment diet and lifestyle changes, and our unique family and survivorship programs will assist your loved ones.

If you have been diagnosed with diabetes or are looking for a second opinion consultation about your treatment, request an appointment online or contact us at 800-826-HOPE. Please visit Making Your First Appointment for more information.

Learn more about diabetes at the Amercian Diabetes Association's website.

Care Team

City of Hope’s renowned physicians and researchers utilize the latest in technology and innovation to treat cancer, coupled with our enduring belief in providing unparalleled compassionate care.

Ken C Chiu, M.D., F.A.C.E.

Clinical Specialties:

  • Endocrinology
Mohamed Ali El-Shahawy, M.D., M.P.H., M.H.A.

Clinical Specialties:

  • Nephrology
Wei Feng, M.D.

Clinical Specialties:

  • Endocrinology
Paul Han, M.S., D.P.M.

Clinical Specialties:

  • Podiatric Surgery
  • Podiatry
Fouad R Kandeel, M.D., Ph.D.

Clinical Specialties:

  • Endocrinology
Azar Khosravi, M.D.

Clinical Specialties:

  • Endocrinology
Behrouz Salehian-Dardashti, M.D.

Clinical Specialties:

  • Endocrinology
Raynald A Samoa, M.D.

Clinical Specialties:

  • Endocrinology

Tests & Treatments

Every patient is different, with different needs. City of Hope treats you as a valued individual. Our entire team works together to bring you precise, state-of-the-art therapy options that will deliver the best outcome for you. We support you every step of the way, helping you and your loved ones manage your condition.

Therapies we offer for patients with diabetes include:

Continuous Glucose Monitoring (CGM)
CGM devices record a patient's blood glucose rigorously over several days to determine patterns and trends, providing information to your care team that can be used to better manage diabetes.

Insulin Therapy
Insulin therapy is the mainstay of type 1 diabetes treatment, and is also used in some cases of type 2 diabetes.  Recombinant human insulin is currently the standard treatment, and may be administered in several ways, such as:

  • Daily injections by the patient or caregiver
  • Insulin infusion in a hospital setting, to manage severe hypoglycemia
  • Insulin pump, using an FDA-approved device that can adjust insulin delivery accordingly to meet the patient's needs

At City of Hope, a diabetologist will review your medical records and meet with you to determine the best insulin administration program for your needs and goals. If you are eligible for an insulin pump, our care team will work closely with you and you loved ones to ensure that the pump is working optimally to maintain long-term blood-glucose control. This includes comprehensive education on pump operation, regular follow-up visits and 24-hour phone access for assistance using the pump.


In addition to insulin, our physicians may also prescribe medications that can stabilize blood glucose levels, help the body better use insulin and/or minimize risk of diabetic complications.

At City of Hope, our diabetes care team will work with the patient and caregivers to maintain optimal blood glucose control, reducing the likelihood of life-threatening episodes and lifelong risk of diabetes-related complications, with minimal impact to quality of life.

Certified Patient Education

City of Hope employs certified diabetes nurse educators who are part of the health care team. Our diabetes educators are also registered nurses whose role is to be a teacher, counselor and coordinator of care for people with diabetes. The diabetes nurse will make sure the patient and, when possible, the patient's family or other support people understand all doctor's orders and the many aspects of the disease. This may include information about medications, how to monitor and interpret blood glucose levels, the importance of exercise, a realistic food plan, dealing with emotions, and when other health team members need to be called upon. Because diabetes is a chronic, progressive and serious disease, support over the long-term is essential to successful management.

Clinical Trials

At City of Hope, we offer our diabetes patients access to drug, surgical and other clinical trials aimed at improving survival rates and enhancing quality of life. In our latest research we are investigating a Chinese herb combination that blocks tumor growth, a targeted therapy that removes enzymes necessary for tumors to develop, and a method to suppress genes that drive cancer growth.

Browse through our clinical trials and research projects here.


Diabetes and Cardiovascular Risk Reduction Program (DCVRRP)
The Department of Clinical Diabetes, Endocrinology and Metabolism offers a comprehensive medical, nutritional and behavioral management program aimed at reducing obesity associated health risks.  This is achieved through safe and consistent weight reduction of high-risk patients who are at least 30% or 50 pounds above ideal body weight and have one or more of the following medical problems: diabetes, high blood pressure, high cholesterol, sleep apnea, heart disease, polycystic ovary syndrome, disabling joint disease, chronic obstructive pulmonary disease, and/or breast cancer one-year after completion of therapy.

Duration of the intensive risk management (phase 1) is six months and transition (phase 2) is six months for a total of one year.  For more information, please contact us at 626-218-2251.

Diabetes Education Program
Research clearly shows that complications of diabetes can, in many cases, be prevented if proper education and treatment are given soon after diagnosis.  For this reason, City of Hope's Department of Clinical Diabetes, Endocrinology & Metabolism is dedicated to educating and helping people with diabetes manage and take control of their disease.  The adult Diabetes Education Program is accredited by the American Diabetes Association. In the four class series, participants learn:

  • Proper diet, exercise and lifestyle changes to help manage diabetes
  • Latest advances in diabetes research and treatment
  • Information to gain a better understanding of the disease, empowering each person to take control of their disease by learning self-management skills

You may be referred by your primary care physician or refer yourself by calling City of Hope.  You can also contact the diabetes nurse educator at 626-218-2251 with any questions and/or to obtain a current schedule of classes.

Sheri & Les Biller Patient and Family Resource Center

Our patients are also encouraged to take advantage of the Sheri & Les Biller Patient and Family Resource Center, which offers a wide array of support and educational services. Patients and loved ones may work with a coordinated group of social workers, psychiatrists, psychologists, patient navigators and spiritual care providers at the center, as well as participate in programs such as music therapy, meditation and many others.

Learn more about these resources at our Supportive Care Medicine site.

Support the Diabetes Program

It takes the help of a lot of caring people to make hope a reality for our patients. City of Hope was founded by individuals' philanthropic efforts more than 100 years ago. Their efforts − and those of our supporters today − have built the foundation for the care we provide and the research we conduct. It enables us to strive for new breakthroughs and better therapies − helping more people enjoy longer, better lives.

For more information on supporting the diabetes program, please contact us at:

City of Hope Philanthropy Department
[email protected]

Or, you can make a gift to support all the research at City of Hope by donating online.


An Expert's Voice

City of Hope experts cover prevention, screening, treatment and other topics on City of Hope’s Breakthrough’s blog.

Back To Top