More than 18,000 Americans are diagnosed with esophageal cancer each year, and more than 15,000 will die from this disease. However, timely diagnosis and intervention can make a dramatic difference in improving survival odds and quality of life.

At City of Hope, our multidisciplinary team takes an integrated, comprehensive approach to diagnosing and treating esophageal cancers, as well as pre-cancerous conditions such as Barrett’s esophagus. Highlights of our program include:

  • experience in minimally-invasive, robotically-assisted surgery for esophageal cancer, reducing complication risk and recovery time
  • endoscopic ultrasound to accurate locate and evaluate tumors
  • radiofrequency ablation to destroy tumor cells in the body
  • highly precise radiation therapy

Additionally, City of Hope patients have access to our comprehensive team of supportive care experts, who can help manage and treat potential quality of life issues, such as trouble with eating, drinking or speaking following treatment.

Nationally Ranked Cancer Center

As one of a handful of institutes to attain the elite designation of Comprehensive Cancer Center by the National Cancer Institute, City of Hope is acknowledged as a leader in esophageal cancer research and treatment. With our decades of experience, specialized therapy protocols and extensive program of clinical trials, newly diagnosed or relapsed patients can find a treatment regimen that is tailored to their needs and gives them the best chance for survival. U.S. News & World Report also named City of Hope as one of the top cancer hospitals in the country for over a decade.

Learn more about esophageal cancer.

Care Team

City of Hope’s renowned physicians and researchers utilize the latest in technology and innovation to treat cancer, coupled with our enduring belief in providing unparalleled compassionate care. If you have been diagnosed with esophageal cancer or are looking for a second opinion consultation about your treatment, request an appointment online or contact us at 800-826-HOPE. Please visit Making Your First Appointment for more information.

Yi-Jen Chen, M.D., Ph.D.

Clinical Specialties:

  • Radiation Oncology
Vincent Chung, M.D., F.A.C.P.

Clinical Specialties:

  • Medical Oncology
Donald S. David, M.D., F.A.C.G.

Clinical Specialties:

  • Gastroenterology
Marwan G. Fakih, M.D.

Clinical Specialties:

  • Medical Oncology
Jae Y. Kim, M.D.

Clinical Specialties:

  • Thoracic Surgery
Dean W. Lim, M.D.

Clinical Specialties:

  • Medical Oncology
James L Lin, M.D.

Clinical Specialties:

  • Gastroenterology
Dan J. Raz, M.D., M.A.S.

Clinical Specialties:

  • Thoracic Surgery

Success Stories

Jim Murphy Success Story image
Jim, esophageal cancer survivor

Now cancer-free for several years, Murphy credits City of Hope with giving him the best chance to fight his disease.

Tests & Treatments

Every patient is different, with different needs. At City of Hope, we treat you as a valued individual. Our entire cervical cancer team works together to bring you advanced surgery, chemotherapy, radiation and supportive care options that will deliver the best outcome for you. You can also enroll in clinical trials for promising therapies that are not offered elsewhere.

Your care continues long after treatment is completed, and we are committed to helping you and your loved ones manage your recovery.

Learn more about treatment options for esophageal cancer, including surgery, external / internal radiation, drug therapy and photodynamic therapy.

Clinical Trials

There is extensive collaboration between clinicians and researchers to develop and evaluate new esophageal cancer therapies designed to improve survival and quality of life outcomes. City of Hope patients have access to a wide variety of clinical trials including new chemotherapy and targeted therapies, novel surgical techniques and new radiation approaches — all focused on enhancing treatment, detection and prevention of esophageal cancer.


When you come to City of Hope, you automatically gain access to an unparalleled array of support services to help you and your family take each step in your lymphoma journey. We can help with all of these concerns, and more:

  • Managing side effects
  • Pain management
  • Navigating the health care system
  • Your emotional, social and spiritual health
  • Staying healthy and active
  • Healthy cooking and eating
  • Healing arts
  • Caregiver skills
  • Dealing with family, school or work stress

Learn more about these resources at our Living with Cancer or Supportive Care Medicine sites.

Additional Resources:

Statistics for Esophageal Cancer
Frequently Asked Questions About Esophageal Cancer
Questions to Ask About Treatment for Esophageal Cancer
Nutrition for Esophageal Cancer Treatment

Support the Esophageal Cancer Program

We deliver exquisite care at the leading edge of cancer treatment. It takes the help of a lot of caring people to make hope a reality for our patients. City of Hope was founded by individuals' philanthropic efforts over 100 years ago. Their efforts - and those of our supporters today - have built the foundation for the care we provide and the research we conduct.

For more information on supporting this specific program, please contact
Joe Komsky
Senior Development Officer
Phone: 626-218-6291
Email: [email protected]

Or, you can make a gift to support all the research at City of Hope by donating online.

An Expert's Voice

City of Hope experts cover prevention, screening, treatment and other cancer topics on City of Hope’s Breakthrough’s blog.

Back To Top