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Myelodysplastic Syndrome


Myelodysplastic Syndrome or MDS refers to a group of blood disorders which strike thousands of Americans every year.

People with MDS are unable to produce the proper amount of mature, healthy blood cells in their bone marrow. MDS develops into leukemia about 30% of the time and can be a life-threatening condition on its own.

It's important to learn about your options as soon as you can. Our dedicated team of myelodysplasia specialists can answer your questions, address your concerns, and design a personalized treatment plan with the most innovative, innovative therapies available anywhere.

If you have been diagnosed with myelodysplastic syndrome or are looking for a second opinion consultation about your treatment, request an appointment online or contact us at 800-826-HOPE. Please visit Making Your First Appointment for more information.

We are committed to treating the whole person, body and soul. City of Hope has an unmatched reputation for coordinated, compassionate care. We bring together a broad array of MDS expertise from multiple disciplines, all under one roof:

  • State-of-the-art diagnostic tools
  • Pioneering drug research and clinical trials
  • Unique transfusion, transplant, chemotherapy and other options

Plus, your care continues long after treatment is complete, with our unique family and survivorship programs. 

Leader in blood disorder treatments

City of Hope is recognized internationally for research and breakthrough treatments of blood cancers. Our Hematologic Malignancies and Stem Cell Transplantation Institute is also one of the largest bone marrow and blood stem cell transplant centers in the country, producing some of the consistently best outcomes. We are designated a Comprehensive Cancer Center by the National Cancer Institute, and for over a decade, U.S. News & World Report has named City of Hope one of the top cancer hospitals in America.



Myelodysplastic Syndrome Treatment Options

Because a stem cell transplant is the only treatment that can cure MDS, it's important to know that City of Hope was among the first facilities to build and develop a transplant program which has performed more than tens of thousands of procedures since 1976. City of Hope has been recognized for superior survival outcomes - one of the only transplant center in the United States with such an achievement.

Every patient is different, with different needs. At City of Hope, we treat you as a valued individual. Our entire team works together to bring you precise, state-of-the-art care options that will deliver the best outcome for you. We support you every step of the way, both during treatment and long after, helping you and your loved ones manage your recovery.

There are different types of treatment for patients with myelodysplastic syndromes.

  • Three types of standard treatment are used:
  • New types of treatment are being tested in clinical trials.
  • Patients may want to think about taking part in a clinical trial.
  • Patients can enter clinical trials before, during, or after starting their treatment.
  • Follow-up tests may be needed.

Learn more about the treatment options for myelodyplastic syndrome disorders.

City of Hope’s renowned physicians and researchers utilize the latest in technology and innovation to treat cancer, coupled with our enduring belief in providing unparalleled compassionate care.


Chatchada Karanes, M.D.

Clinical Specialties

  • Hematology/Oncology
Ryotaro Nakamura, M.D.

Clinical Specialties

  • Hematology/Oncology
Margaret R O'Donnell, M.D., F.R.C.P.C.

Clinical Specialties

  • Hematology/Oncology
Eileen P. Smith, M.D.

Clinical Specialties

  • Hematology/Oncology
Anthony S. Stein, M.D.

Clinical Specialties

  • Hematology/Oncology

Myelodysplastic Syndrome Clinical Trials

We offer access to a wide variety of clinical trials not always available to the general public.

Our latest research is focused on eliminating graft-versus-host disease in transplant patients, and reducing the risk of MDS developing into leukemia.

Browse through some of our clinical trials and research projects.


Living with Myelodysplastic Syndrome (MDS)

When you come to City of Hope, you automatically gain access to an unparalleled array of support services to help you and your family take each step in your MDS journey. We can help with all of these concerns, and more:

  • Managing side effects

  • Pain management

  • Navigating the health care system

  • Your emotional, social and spiritual health

  • Staying healthy and active

  • Healthy cooking and eating

  • Healing arts

  • Caregiver skills

  • Dealing with family, school or work stress

Learn more about these resources at our Living with Cancer or Supportive Care Medicine sites.

Join a community of people who understand what you’re going through…

The Leukemia & Lymphoma Society’s Community is an online community of people living with or supporting someone with blood cancer. Get connected and share your voice to drive change.


Myelodysplastic Syndrome

Hear musician George Winston talk about his remarkable experience at City of Hope, where he battled and overcame thyroid cancer, basal cell carcinoma, and myelodysplastic syndrome.