Myelodysplastic Syndrome or MDS refers to a group of blood disorders which strike about 13,000 Americans every year.
People with MDS are unable to produce the proper amount of mature, healthy blood cells in their bone marrow. MDS develops into leukemia about 30% of the time and can be a life-threatening condition on its own.
If you've been diagnosed with MDS, talk to us. It's important to learn about your options as soon as you can. Our dedicated team of myelodysplasia specialists can answer your questions, address your concerns, and design a personalized treatment plan with the most innovative, cutting-edge therapies available anywhere. At City of Hope, we are committed to treating the whole person, body and soul. We have an unmatched reputation for coordinated, compassionate care. We bring together a broad array of MDS expertise from multiple disciplines, all under one roof:
  • State-of-the-art diagnostic tools
  • Pioneering drug research and clinical trials
  • Unique transfusion, transplant, chemotherapy and other options
Plus, your care continues long after treatment is complete, with our unique family and survivorship programs. 
City of Hope is recognized internationally for research and breakthrough treatments of leukemia. Our Hematologic Malignancies and Stem Cell Transplantation Institute is also one of the largest transplant centers in the country, producing some of the consistently best outcomes. We are designated a Comprehensive Cancer Center by the National Cancer Institute, and for over a decade, U.S. News & World Report has named City of Hope one of the top cancer hospitals in America.

If you have been diagnosed with myelodysplastic syndrome or are looking for a second opinion consultation about your treatment, request an appointment online or contact us at 800-826-HOPE. Please visit Making Your First Appointment for more information.


Care Team

City of Hope’s renowned physicians and researchers utilize the latest in technology and innovation to treat cancer, coupled with our enduring belief in providing unparalleled compassionate care.

Generic Faculty Photo
Chatchada Karanes, M.D.

Clinical Specialties:

  • Hematology/Oncology
Ryotaro Nakamura
Ryotaro Nakamura, M.D.

Clinical Specialties:

  • Hematologic Malignancies
  • Lymphoma
  • Leukemia
  • Myelodysplastic Syndrome
  • Aplastic Anemia
Margaret O Donnell headshot photo
Margaret R O'Donnell, M.D., F.R.C.P.C.

Clinical Specialties:

  • Hematology/Oncology
Anthony S Stein, M.D.

Clinical Specialties:

  • Hematology/Oncology

Tests & Treatments

Because a stem cell transplant is the only treatment that can cure MDS, it's important to know that City of Hope was among the first facilities to build and develop a transplant program which has performed more than 12,000 procedures since 1976. City of Hope has been recognized for superior survival outcomes for nine consecutive years—the only transplant center in the United States with such an achievement.

Every patient is different, with different needs. At City of Hope, we treat you as a valued individual. Our entire team works together to bring you precise, state-of-the-art care options that will deliver the best outcome for you. We support you every step of the way, both during treatment and long after, helping you and your loved ones manage your recovery.

Learn more about treatment options for myelodyplastic syndrome disorders, such as chemotherapy, transfusion therapy and bone marrow / stem cell transplantation.


When you come to City of Hope, you automatically gain access to an unparalleled array of support services to help you and your family take each step in your MDS journey. We can help with all of these concerns, and more:
  • Managing side effects
  • Pain management
  • Navigating the health care system
  • Your emotional, social and spiritual health
  • Staying healthy and active
  • Healthy cooking and eating
  • Healing arts
  • Caregiver skills
  • Dealing with family, school or work stress
Learn more about these resources at our Living with Cancer or Supportive Care Medicine sites.
Support the Myelodysplastic Syndrome Program

We deliver exquisite care at the leading edge of cancer treatment. It takes the help of a lot of caring people to make hope a reality for our patients. City of Hope was founded by individuals' philanthropic efforts over 100 years ago. Their efforts - and those of our supporters today - have built the foundation for the care we provide and the research we conduct.
For more information on supporting this specific program, please contact
Or, you can make a gift to support all the research at City of Hope by donating online.
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