Each year, about 10,000 children in the U.S. are diagnosed with cancer.

Most pediatric cancers grow rapidly but also respond very well to chemotherapy. Survival rates are excellent, averaging 80 percent or higher. But cancers in children can also trigger long-term health challenges later in life, making follow-up care and regular monitoring especially important.

If your child has been diagnosed with cancer, contact us right away. Because of the special nature of pediatric cancers, treatment needs to begin as quickly as possible. And because of the unique challenges and needs of children with cancer, you should seek out a specialized facility with the staff and expertise to treat young people.

City of Hope specializes in the treatment of cancers and blood disorders that occur most often in children, adolescents and young adults, including:

City of Hope is a member of the Children's Oncology Group which maintains rigorous staffing, services and facilities standards for treating children's cancer. 90 percent of all pediatric cancer cases in the U.S. are treated at COG institutions. Through COG, City of Hope has access to the nation's largest group of clinical trials for pediatric and adolescent cancers.

At City of Hope, your child will be cared for by a dedicated team of world-class professionals specially trained in pediatric cancer. Pediatric oncologists, hematologists, surgeons, radiation therapists, pathologists and others work together to develop targeted and effective treatment plans, while professionals in psychology, social work, child life, physical, occupational and recreational therapy, music therapy, and school reintegration provide support to patients and their loved ones.

We also offer unique support programs and special facilities for adolescents and young adults, to assist with the often difficult transition into adulthood at the time of illness.

Plus, your child's care continues long after treatment is complete, with regular monitoring and support services through our Childhood Cancer Survivorship Program.

Learn more about childhood cancers.

Request an Appointment

If your child have been diagnosed with a pediatric cancer or are looking for a second opinion consultation about your treatment, request an appointment online or contact us at 800-826-HOPE. Please visit Making Your First Appointment for more information.

Care Team

City of Hope’s renowned pediatric physicians and researchers utilize the latest in technology and innovation to treat cancer, coupled with our enduring belief in providing unparalleled compassionate care. Call 800-826-HOPE or go online to request an appointment.

Clarke Paul Anderson, M.D.

Clinical Specialties:

  • Pediatric Hematology/Oncology
Saro H. Armenian, D.O., M.P.H.

Clinical Specialties:

  • Pediatric Hematology/Oncology
Julie F DiMundo, D.O.; F.A.A.P.

Clinical Specialties:

  • Hospital Medicine
  • Pediatric Critical Care Medicine
Nadia P Ewing, M.D.

Clinical Specialties:

  • Pediatric Hematology - Oncology
Theresa Harned, M.D.

Clinical Specialties:

  • Pediatric Hematology/Oncology
Nicole Karras headshot
Nicole A Karras, M.D.

Clinical Specialties:

  • Pediatric Hematology - Oncology
Anna Pawlowska, M.D.

Clinical Specialties:

  • Pediatric Hematology/Oncology
Joseph Rosenthal, M.D., M.H.C.M.

Clinical Specialties:

  • Pediatric Hematology/Oncology
Judith K. Sato, M.D.

Clinical Specialties:

  • Pediatric Hematology/Oncology
John A Zaia, M.D.

Clinical Specialties:

  • Pediatric Infectious Disease

Success Stories

Hannah Komai Success Story Image
Hannah, bone cancer survivor

Now cancer-free, Hannah draws inspiration from the care she received at City of Hope and is in college pursuing a nursing degree in college.

Nicole Schulz Success Story Image
Nicole, leukemia survivor

After two bone marrow transplants and tremendous perseverance, Nicole is back to living the life she once knew – and making up for lost time.

Gavin's Wish: Meet My Bone Marrow Donor

A 6-year old boy is given the opportunity to meet the bone marrow donor who saved his life.

Adi and Karli Success Story Image
Adi and Kari's Story

Adi was diagnosed with Stage 4 neuroblastoma, a cancer of the nervous system that started on his adrenal gland and spread to his bone marrow.

Tests & Treatments

City of Hope specializes in the treatment of childhood cancers and blood disorders, including:

  • Multiple types of leukemia, including acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML) and chronic myelogenous leukemia (CML)
  • Hodgkin and non-Hodgkin lymphomas
  • Musculoskeletal tumors, such as osteosarcoma, Ewing sarcoma, chondrosarcoma, rhabdomyosarcoma and soft tissue sarcomas
  • Brain tumors: astrocytoma, medulloblastoma and retinoblastoma
  • Neuroblastoma
  • Reproductive system tumors: Wilm’s tumor and germ cell tumors
  • Head and neck cancers, including cancers of the oral and nasal cavities, throat, sinuses, thyroid and salivary glands
  • Bleeding and clotting diseases: hemophilia, Idiopathic Thrombocytopenic Purpura (ITP), blood clots and platelet disorders
  • Red blood cell disorders: various forms of anemia, sickle cell disease and iron deficiency
  • Bone marrow and neutrophil disorders: aplastic anemia, storage diseases and neutropenia
  • Hematopoietic cell transplant (HCT), bone marrow transplant and cord blood transplant

With the ever-increasing number of survivors of childhood cancer, we also emphasize long-term survivorship, providing continued surveillance to monitor and proactively address the long-term effects of childhood cancer.

Clinical Trials


Living with Cancer

When you come to City of Hope, you automatically gain access to an unparalleled array of support services to help you and your family take each step during and after treatment. Learn more about these resources at our Living with Cancer or Supportive Care Medicine sites.

Childhood Cancer Suvivorship Program

The Childhood Cancer Survivorship Program at City of Hope provides specialized follow-up care for patients who have completed treatment for cancer or a similar illness that was diagnosed at age 21 or younger.  Patients who participate in this program are seen every year in a clinic specially designed to meet the needs of childhood cancer survivors.  Patients are evaluated by a team of health care professionals who are experts in survivorship issues, including a physician or nurse practitioner, a dietitian, and a psychologist or social worker.

Patients in this program will receive careful monitoring for possible health problems that can sometimes occur after cancer treatment. They will also have the opportunity to talk with the Survivorship Program team about the treatment that they received for cancer, its potential impact on their health, and ways to stay as healthy as possible.

Each patient will receive a personalized record of the details of their cancer treatment. They will also be provided guidelines for continued monitoring, including recommendations for preventive care and information about available resources and services.  The goal is to help each survivor stay healthy and to prevent any subsequent problems or detect them as early as possible so they can be more easily treated.

This program is carried out in collaboration with each patient’s primary health care and treatment team and is part of the research program here at City of Hope. For more information, please call 626-471-9220 or email us at [email protected].

Additional Resources:

Coping with a Diagnosis of Cancer in Children
Pain Management and Chldren
Nutritional Requirements for a Child with Cancer
Questions to Ask Your Child's Health Care Provider

Support the Pediatrics Program

City of Hope delivers exquisite care at the leading edge of pediatric cancer treatment. It takes the help of a lot of caring people to make hope a reality for our patients. City of Hope was founded by individuals' philanthropic efforts over 100 years ago. Their efforts - and those of our supporters today - have built the foundation for the care we provide and the research we conduct.

For more information on supporting the Pediatric Cancers Program, please contact Julie Hara. Or, you can make a gift to support all the research at City of Hope by donating online.

An Expert's Voice

City of Hope experts cover prevention, screening, treatment and other cancer topics on City of Hope’s Breakthrough’s blog.

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