A National Cancer Institute-designated Comprehensive Cancer Center

Make an appointment: 800-826-HOPE
Clinical Protocol & Data Management Core (CPDMC) Bookmark and Share

Clinical Protocol & Data Managment Core (CPDMC)

Co-Director: Adina Londrc, M.D.
Co-Director: Ajay Shah, Ph.D.
Core Managers: Karen Rickard & Gabe Peterson


The Clinical Protocol and Data Management Core (CPDMC) is led by Adina Londrc, M.D. (Director of Clinical Research Information Support), and Ajay Shah, Ph.D. (Director of Research Informatics) with Karen Rickard and Gabe Peterson serving as Core Managers. The Core provides centralized infrastructure and support for effective, efficient conduct of clinical research.

The CPDMC offers comprehensive services to COH Cancer Center members including: protocol document management, electronic data capture, standardized clinical research staff training and education, honest broker process for accessing tissue samples, study recruitment tracking, patient safety decision support tools, data quality assurance and monitoring, multi-site coordination, and customized and routine reports.
 
CPDMC Core Services
Protocol Management
 
  • Protocol Document Management, i.e. Clinical Trials On-lineSM
  • Clinical Trials Reporting Program (CTRP) Reporting
  • Clinical Trials Management Systems
  • Research Informatics Architecture

Electronic Data Capture
 
  • Case Report FormDevelopment
  • Data Collection Grid Creation
  • Forms Instructions
  • Metadata Management
  • Electronic Case Report Form Construction
  • Laboratory Data Capture
  • Enterprise Data Warehouse

Training
 
  • Protocol Management Training
  • Case Report Form Training
  • Training Workshops & In-Services
  • Training Tools and Manuals
  • E-Learning
  • Communities of Practice

Study Recruitment Management
 
  • Subject Registration
  • Accrual Monitoring
  • Online Subject Registration
  • Online Informed Consent Linkage

Study Conduct Management
 
  • Data Quality Monitoring
  • Multi-Site Coordination
  • Audit Preparation
  • Programmatic Edit Checks
  • Subject Safety Decision Support

Reporting and Analysis Support
 
  • Monitoring & Validating Accruals
  • Data Curation for Statistical Analysis
  • Database Lock
  • Decision Support
  • Data Mart Creation
  • Online Informed Consent Linkage

Data Integration Querying
 
  • De-identified Cohort Discovery (iCoDE)
  • Cancer Registry Data
  • Diagnosis and Procedures
  • Tissue Specimen Information
 

Abstract for Grants

The Clinical Protocol and Data Management Core (CPDMC) is a collaborative integrated unit staffed by professionals with expertise in protocol data management and clinical research informatics, to provide centralized infrastructure and support for the effective efficient conduct of clinical research. Working closely with the Biostatistics Core, this team blends technical and scientific expertise to provide City of Hope investigators with world-class research support and informatics solutions for clinical trials, observational studies, and outcomes research. The CPDMC offers comprehensive services to COH Cancer Center members including: protocol document management, electronic data capture, standardized clinical research staff training and education, honest broker process for accessing tissue samples, study recruitment tracking, patient safety decision support tools, data quality assurance and monitoring, multi-site coordination, and customized and routine reports.
 
The CPDMC provides input into developing protocols with respect to practicality and appropriateness of protocol management, study calendar, and data collection issues. Data Quality Monitors ensure that study research staff are fully trained in protocol management, data collection, and overall study conduct according to Good Clinical Practice (GCP) and COH policies. The CPDMC database monitors ensure that protocol and patient registration is carried out according to NCI guidelines.
 
Key informatics services provided include: Clinical Trial Management Systems to manage planning, execution, and reporting of clinical research studies; Electronic Data Capture to provide electronic case report forms; and Clinical Research Decision Support to translate data into scientific decisions. Our emerging work on Translational Research Informatics includes implementation of the enterprise data warehouse, i2b2 open source system for cohort selection for tissue correlative studies, along with Electronic Lab Notebook and Laboratory Information Management Systems.
 
For all these functions we use international architectural and vocabulary standards and project management methodologies to deliver clinical and translational informatics applications. In summary, the CPDMC delivers resources, education, and information management processes to establish best practices in accordance with FDA, GCP, regulatory requirements such as 21CFR Part 11, and international data standards such as HL7, SNOMED, and LOINC.

Pricing

Pricing

Prices and availability vary. Please Contact Us for current information.

Comprehensive Cancer Center
In recognition of our excellence in a broad range of new approaches to cancer research and treatment—and our outreach to the community— the National Cancer Institute (NCI) has designated City of Hope a Comprehensive Cancer Center—one of just a handful of elite institutions nationwide.

Using the Facility

The Core's services are available to all City of Hope faculty, with City of Hope Cancer Center members receiving the highest priority.

To request service or discuss how we can facilitate your scientific goals, please Contact Us.
 

Clinical Protocol & Data Managment Core Team

Clinical Protocol & Data Management Core (CPDMC)

Clinical Protocol & Data Managment Core (CPDMC)

Co-Director: Adina Londrc, M.D.
Co-Director: Ajay Shah, Ph.D.
Core Managers: Karen Rickard & Gabe Peterson


The Clinical Protocol and Data Management Core (CPDMC) is led by Adina Londrc, M.D. (Director of Clinical Research Information Support), and Ajay Shah, Ph.D. (Director of Research Informatics) with Karen Rickard and Gabe Peterson serving as Core Managers. The Core provides centralized infrastructure and support for effective, efficient conduct of clinical research.

The CPDMC offers comprehensive services to COH Cancer Center members including: protocol document management, electronic data capture, standardized clinical research staff training and education, honest broker process for accessing tissue samples, study recruitment tracking, patient safety decision support tools, data quality assurance and monitoring, multi-site coordination, and customized and routine reports.
 
CPDMC Core Services
Protocol Management
 
  • Protocol Document Management, i.e. Clinical Trials On-lineSM
  • Clinical Trials Reporting Program (CTRP) Reporting
  • Clinical Trials Management Systems
  • Research Informatics Architecture

Electronic Data Capture
 
  • Case Report FormDevelopment
  • Data Collection Grid Creation
  • Forms Instructions
  • Metadata Management
  • Electronic Case Report Form Construction
  • Laboratory Data Capture
  • Enterprise Data Warehouse

Training
 
  • Protocol Management Training
  • Case Report Form Training
  • Training Workshops & In-Services
  • Training Tools and Manuals
  • E-Learning
  • Communities of Practice

Study Recruitment Management
 
  • Subject Registration
  • Accrual Monitoring
  • Online Subject Registration
  • Online Informed Consent Linkage

Study Conduct Management
 
  • Data Quality Monitoring
  • Multi-Site Coordination
  • Audit Preparation
  • Programmatic Edit Checks
  • Subject Safety Decision Support

Reporting and Analysis Support
 
  • Monitoring & Validating Accruals
  • Data Curation for Statistical Analysis
  • Database Lock
  • Decision Support
  • Data Mart Creation
  • Online Informed Consent Linkage

Data Integration Querying
 
  • De-identified Cohort Discovery (iCoDE)
  • Cancer Registry Data
  • Diagnosis and Procedures
  • Tissue Specimen Information
 

Abstract for Grants

Abstract for Grants

The Clinical Protocol and Data Management Core (CPDMC) is a collaborative integrated unit staffed by professionals with expertise in protocol data management and clinical research informatics, to provide centralized infrastructure and support for the effective efficient conduct of clinical research. Working closely with the Biostatistics Core, this team blends technical and scientific expertise to provide City of Hope investigators with world-class research support and informatics solutions for clinical trials, observational studies, and outcomes research. The CPDMC offers comprehensive services to COH Cancer Center members including: protocol document management, electronic data capture, standardized clinical research staff training and education, honest broker process for accessing tissue samples, study recruitment tracking, patient safety decision support tools, data quality assurance and monitoring, multi-site coordination, and customized and routine reports.
 
The CPDMC provides input into developing protocols with respect to practicality and appropriateness of protocol management, study calendar, and data collection issues. Data Quality Monitors ensure that study research staff are fully trained in protocol management, data collection, and overall study conduct according to Good Clinical Practice (GCP) and COH policies. The CPDMC database monitors ensure that protocol and patient registration is carried out according to NCI guidelines.
 
Key informatics services provided include: Clinical Trial Management Systems to manage planning, execution, and reporting of clinical research studies; Electronic Data Capture to provide electronic case report forms; and Clinical Research Decision Support to translate data into scientific decisions. Our emerging work on Translational Research Informatics includes implementation of the enterprise data warehouse, i2b2 open source system for cohort selection for tissue correlative studies, along with Electronic Lab Notebook and Laboratory Information Management Systems.
 
For all these functions we use international architectural and vocabulary standards and project management methodologies to deliver clinical and translational informatics applications. In summary, the CPDMC delivers resources, education, and information management processes to establish best practices in accordance with FDA, GCP, regulatory requirements such as 21CFR Part 11, and international data standards such as HL7, SNOMED, and LOINC.

Pricing

Pricing

Pricing

Prices and availability vary. Please Contact Us for current information.

Comprehensive Cancer Center
In recognition of our excellence in a broad range of new approaches to cancer research and treatment—and our outreach to the community— the National Cancer Institute (NCI) has designated City of Hope a Comprehensive Cancer Center—one of just a handful of elite institutions nationwide.

Using the Facility

Using the Facility

The Core's services are available to all City of Hope faculty, with City of Hope Cancer Center members receiving the highest priority.

To request service or discuss how we can facilitate your scientific goals, please Contact Us.
 

Clinical Protocol & Data Managment Core Team

Clinical Protocol & Data Managment Core Team

Research Shared Services

City of Hope embodies the spirit of scientific collaboration by sharing services and core facilities with colleagues here and around the world.
 

Recognized nationwide for its innovative biomedical research, City of Hope's Beckman Research Institute is home to some of the most tenacious and creative minds in science.
City of Hope is one of only 41 Comprehensive Cancer Centers in the country, the highest designation awarded by the National Cancer Institute to institutions that lead the way in cancer research, treatment, prevention and professional education.
Learn more about City of Hope's institutional distinctions, breakthrough innovations and collaborations.
Support Our Research
By giving to City of Hope, you support breakthrough discoveries in laboratory research that translate into lifesaving treatments for patients with cancer and other serious diseases.
 
 
 
 
Media Inquiries/Social Media

For media inquiries contact:

Dominique Grignetti
800-888-5323
dgrignetti@coh.org

 

For sponsorships inquiries please contact:

Stefanie Sprester
213-241-7160
ssprester@coh.org

Christine Nassr
213-241-7112
cnassr@coh.org

 
CONNECT WITH US
Facebook  Twitter  YouTube  Blog
 
NEWS & UPDATES
  • Gliomas, a type of tumor that grows in the brain, are very difficult to treat successfully due to their complex nature. That might not always be the case. First some background: The most aggressive and common type of primary brain tumor in adults is glioblastoma. Although the brain tumor mass can often be remov...
  • Cutaneous T cell lymphomas are types of non-Hodgkin lymphoma that arise when infection-fighting white blood cells in the lymphatic system – called lymphocytes – become malignant and affect the skin. The result is rashes and, sometimes, tumors, which can be mistaken for other dermatological conditions. In a smal...
  • Weighing your breast cancer risk? One study suggests a measure to consider is skirt size. A British study suggests that for each increase in skirt size every 10 years after age 25, the five-year risk of developing breast cancer postmenopause increases from one in 61 to one in 51 – a 77 percent increase in risk....
  • Runners prize medals for 5Ks and marathons. Becky Stokes has a medal she cherishes from a very different kind of race: the marathon of treatments necessary to beat her aggressive triple-negative breast cancer. Just a week ago, she completed her last radiation treatment, and danced in the hospital with the staff...
  • Rob Darakjian was diagnosed with acute lymphoblastic leukemia at just 19 years old. He began chemotherapy and was in and out of the hospital for four months. After his fourth round of treatment, he received a bone marrow transplantation from an anonymous donor. Today, he’s cancer free. Darakjian’s s...
  • The environment plays a role in causing cancer – this much we know. But scientists are still trying to understand what that role is, what environmental factors are in play and how precisely those factors are linked to cancer. Now City of Hope researchers have unlocked a clue as to how one carcinogen triggers ca...
  • Jonathan Yamzon, M.D., assistant clinical professor of surgery in the Division of Urology and Urologic Oncology, explains his approach to what’s known as “active surveillance” of men with prostate cancer. Patients need to be educated about their treatment options, he writes. Active surveillanc...
  • For most prostate cancer patients, surgery or radiation therapy is the initial and primary treatment against the disease. But some patients can benefit from chemotherapy and hormone therapy too, especially if there are signs of a relapse or if the cancer has spread beyond the prostate gland. Here, Cy Stein, M.D...
  • Cancer research has yielded scientific breakthroughs that offer patients more options, more hope for survival and a higher quality of life than ever before. The 14.5 million cancer patients living in the United States are living proof that cancer research saves lives. Now, in addition to the clinic, hospital an...
  • Advances in cancer treatment, built on discoveries made in the laboratory then brought to the bedside, have phenomenally changed the reality of living with a cancer diagnosis. More than any other time in history, people diagnosed with cancer are more likely to survive and to enjoy a high quality of life. Howeve...
  • While health care reform has led to an increase in the number of people signing up for health insurance, many people remain uninsured or are not taking full advantage of the health benefits they now have. Still others are finding that, although their premiums are affordable, they aren’t able to see the do...
  • Kidney cancer rates and thyroid cancer rates in adults have continued to rise year after year. Now a new study has found that incidence rates for these cancers are also increasing in children — particularly in African-American children. The study, published online this month in Pediatrics, examined childhood ca...
  • Thyroid cancer has become one of the fastest-growing cancers in the United States for both men and women. The chance of being diagnosed with the cancer has nearly doubled since 1990. This year an estimated 63,000 people will be diagnosed with thyroid cancer in the United States and nearly 1,900 people will die ...
  • Older teenagers and young adults traditionally face worse outcomes than younger children when diagnosed with brain cancer and other central nervous system tumors. A first-of-its-kind study shows why. A team of researchers from the departments of Population Sciences and Pathology at City of Hope recently examine...
  • Cancer treatment can take a toll on the mouth, even if a patient’s cancer has nothing to do with the head or throat, leading to a dry mouth, or a very sore mouth, and making it difficult to swallow or eat. Here’s some advice from the National Cancer Institute (NCI)  on how to ease cancer-related dis...