Park, J.R., DiGiusto, D.L., Slovak, M., Wright, C., Naranjo, A., Wagner, J., Meechoovet, H.B., Bautista, C., Chang, W.C., Osterberg, J. and Jensen M.C. Adoptive Transfer of Chimeric Antigen Receptor Re-directed Cytolytic T Lymphocyte Clones in Patients with Neuroblastoma: A first in Children Pilot Feasibility/Safety Trial. 2007 Molecular Therapy 15(4):825-33.

Burton, L, Tran, C., Russom, D. Wagner, J., Jensen, M., Forman, S. and DiGiusto, D. Manufacturing of Large Numbers of Gene-Modified T-Cells: An Approach to Improving Product Safety While Increasing Production Capacity. 2007. J. Immunotherapy. Vol 30:6 644-654.

David L. DiGiusto and Laurence J. Cooper. Preparing Clinical-Grade Antigen-Specific T-cells for Adoptive- Immunotherapy Trials. 2007 Cytotherapy. 9(7):613-629.

Human Marrow-Derived Mesodermal Progenitor Cells Generate Insulin-Secreting Islet-Like Clusters In Vivo. Cuiwei Ai, Ivan Todorov, Marilyn L. Slovak, David DiGiusto, Stephen J. Forman, Chu-Chih Shih. 2007 Stem Cells and Development.  Vol. 16:5: 757-770.

Cooper LJ, Ausubel L, Gutierrez M, Stephan S, Shakeley R, Olivares S, Serrano L, Burton L, Jensen M, Forman S, DiGiusto D: Manufacturing of Gene Modified Cytotoxic t Lumphocytes for Autologous Cellular Therapy for Lymphoma. 2006; Vol 8:2 105-117.

Cooper LJN, Kalos M, DiGiusto D, Brown C, Forman SJ, Raubitschek A, Jensen MC: T-Cell Genetic Modification for Re-Directed Tumor Recognition. In: Cancer Chemotherapy & Biological Response Modifiers. 2005;22:293-324.

Cooper LJ, Al-Kadhimi Z, DiGiusto D, Kalos M, Colcher D, Raubitschek A, Forman SJ, Jensen MC. 2004. Development and application of CD19-specific T cells for adoptive immunotherapy of B cell malignancies.  Blood Cells Mol Dis. Jul-Aug:33(1):83-9.

Shih CC, DiGiusto D, Mamelak A, LeBon T, Forman SJ:  Hematopoietic Potential of Neural Stem Cells: Plasticity Versus Hetergeneity.  Leukemia and Lymphoma. 43: 2263-2268, 2002.

Shih CC, DiGiusto D, Forman SJ: Ex vivo expansion of transplantable human hematopoietic stem cells: where do we stand in the year 2000? J Hematother Stem Cell Res. 9: 621-628, 2000.

Plavec I, Voytovich A, Moss K, Webster D, Hanley MB, Escaich, Ho KE, Böhnlein E, DiGiusto D:  Sustained Retroviral Gene Marking and Expression in Lymphoid and Myeloid Cells Derived from Transduced Hematopoietic Progenitor Cells. Gene Therapy 3:717-724. 1996.

Young J, DiGiusto D, Backer M:  In Vitro Characterization of Fetal Hematopoietic Stem Cells: Range and Kinetics of Cell Production from Individual Stem Cells. Biotechnology and Bioengineering 50:465-478, 1996.

DiGiusto D, Lee R, Moon J, Moss K, O’Toole T, Voytovich A, Webster D, Mule JJ:  Hematopoietic potential of Cryopreserved and Ex-vivo Manipulated Umbilical Cord Blood Progenitor cells Evaluated In Vitro and In Vivo. Blood 87:1261-1271, 1996.

Young JC, Varma A, DiGiusto D, Backer MP:  Retention of Quiescent Hematopoietic Cells with High Proliferative Potential During Ex-Vivo Stem Cell Culture. Blood 87:545-556, 1996.

Tsukamoto A, Weissman I, Chen B, DiGiusto D, Baum C, Hoffman R, Uchida N:  Phenotypic and functional analysis of stem cells in mouse and man. in: Hematopoietic Stem Cells: Biology and Therapeutic Application. Levitt/Mertelsmann Eds. Marcel Decker, New York, 1995.

Murray L, DiGiusto D, Chen B, Chen S, Combs J, Conti A, Galy A, Negrin R, Tricot G, Tsukamoto A:  Analysis of human hematopoietic stem cell populations Blood Cells. 20:364-370, 1994.

DiGiusto D, Chen S, Combs J, Webb S, Tsukamoto A, Chen B, Galy AHM:  Human fetal bone marrow early progenitors for T, B, and Myeloid cells are found exclusively in the population expressing high levels of the CD34 antigen. Blood. 84:421-432, 1994.

DiGiusto D, Palmer E:  An analysis of sequence variation in ß chain framework and complementary determining regions of an alloreactive T cell receptor. Molecular Immunology. 31:693-699, 1994.

Choi Y, Herrman A, DiGiusto D, Wade T, Marrack P, Kappler J:  Residues within the variable region of the T cell receptor ß chain that interact with S. Aureas toxin superantigen. Nature. 346:471, 1990.

Ransom, JT, Pasternak JA, Sandoval VM, Chien M, DiGiusto DL, Cambier JC:  Increased plasma membrane permeability to calcium in anti-Ig stimulated B lymphocytes is dependent upon activation of phosphoinositide hydrolysis. J. Immunology. 140:3150-3155, 1988.

Ransom, JT, DiGiusto D, Cambier JC:  Flow Cytometric Analysis of Intracellular CalciumMobilization. In: Cellular Regulators: Calcium and Calmodulin Binding Proteins. A. Means and P.M. Conn, Eds. Methods in Enzymology, Academic Press, NY vol. 141:53-63, 1986.

Ransom, JT, DiGiusto D, Cambier JC:  Single cell analysis of Calcium mobilization in anti-receptor antibody stimulated B lymphocytes. J. Immunology. 136:54, 1986.

Roehm, N.L., Herron L, Cambier JC, DiGiusto D, Haskins K, Kappler J, Marrack P:  The antigenspecific major histocompatibility restricted receptor on T cells. VII. Distribution on Thymus and Peripheral T cells. Cell. 38:577-583, 1984.

Havran WL, DiGiusto DL, Cambier JC:  MIgM/mIgD Molar ratios on mouse B cells: Mean mIgD expression exceeds mIgM by 10-fold on most splenic B cells. J. Immunology. 132:1712, 1983.


This is a partial list. Full publications list available upon request. Information on this page may be self-reported and is subject to change at any time. Last updated: 06/08