Genetics of diabetes:
Hattersley AT, Turner RC, Permutt MA, Patel P, Tanizawa Y, Chiu KC, O'Rahilly S, Watkins PJ, Wainscoat JS: Linkage of type 2 diabetes to the glucokinase gene. Lancet 1992;339:1307- 1310.
Chiu KC, Province MA, Permutt MA: The glucokinase gene is a genetic marker for non-insulindependent diabetes mellitus in American blacks. Diabetes 1992;41:843-849.
Mueckler M, Kruse M, Strube M, Riggs AC, Chiu KC, Permutt MA: A mutation in the Glut2 glucose transporter gene of a diabetic patient abolishes transport activity. Journal of Biological Chemistry 1994;269:17765-17767.
Glaser B, Chiu KC, Anker R, Nestorowicz A, Landau H, Ben-Bassat H, Shlomai Z, Kaiser N, Thornton PS, Stanley CA, Spielman RS, Gogolin-Ewens K, Cerasi E, Baker L, Rice J, Donis- Keller H, Permutt MA: Familial hyperinsulinism maps to chromosome 11p14-15.1, 30 cM centromeric to the insulin gene. Nature Genetics 1994;7:185-188.
Chiu KC, Chuang L-M, Ryu JM, Tsai GP, Saad MF: The I27L amino acid polymorphism of the hepatic nuclear factor-1alpha is a risk factor for insulin resistance. Journal of Clinical Endocrinology and Metabolism 2000;85:2178-2183.
Chang Y-C, Chang TJ, Jiang Y-D, Kuo S-S, Lee K-C, Chiu KC, Chuang L-M: Association Study of The Genetic Polymorphisms of The Transcription Factor7- like 2 (TCF7L2) Gene and Type 2 Diabetes in the Chinese Population. Diabetes 2007:56:2631-2637.
Liu P-H, Chang Y-C, Jiang Y-D, Chen WJ, Chang T-J, Kuo S-S, Lee K-C, Hsiao P-C, Chiu KC, Chuang L-M: Genetic Variants of TCF7L2 are Associated with Insulin Resistance and Related Metabolic Phenotypes in Taiwanese Adolescents and Caucasian Young Adults. Journal of Clinical Endocrinology and Metabolism 2009;94(9):3575–3582.
Vitamin D and diabetes:
Chang TJ, Lei HH, Yeh JI, Chiu KC, Lee KC, Chen MC, Tai TY, Chuang LM: Vitamin D receptor gene polymorphisms influence susceptibility to type 1 diabetes mellitus in the Taiwanese population. Clinical Endocrinology 2000;52:575-580.
Chiu KC, Chuang L-M, Lee NP, Ryu JM, McGullam JL, Tsai GP, Saad MF: Insulin sensitivity is inversely correlated with plasma intact parathyroid hormone. Metabolism 2000;49:1501-1505
Chiu KC, Chuang L-M, Yoon C: The vitamin D receptor polymorphism in the translation initiation codon is a risk factor for insulin resistance in glucose tolerant Caucasians. BMC Medical Genetics 2001;2:2 (8 printed pages).
Chiu KC, Chu A, Go VL, Saad MF: Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction. American Journal of Clinical Nutrition 2004;79:820-825.
Ou H-Y, Karnchansorn R, Lee LZ, Chiu KC: Interaction of BMI with vitamin D and insulin sensitivity. European Journal of Clinical Investigation 2011; 41(11):1195-201.
Karnchansorn R, Ou H-Y, Chiu KC: Plasma 25-hydroxyvitamin D levels are favorably associated with beta cell function. Pancreas 2012;41:863-868.
Epidemiology of diabetes:
Chiu KC, Cohan P, Lee NP, Chuang L-M: Insulin sensitivity differs among different ethnic groups with a compensatory response in beta cell function. Diabetes Care 2000;23:1353-1358.
Chiu KC, Lee NP, Cohan P, Chuang L-M: Beta cell function declines as aging but not insulin sensitivity. Clinical Endocrinology 2000;53:569-575.
Chiu KC, Chuang L-M, Yoon C: Comparison of measured and estimated indices of insulin sensitivity and beta cell function: Impact of ethnicity on insulin sensitivity and beta cell function in glucose tolerant and normotensive subjects. Journal of Clinical Endocrinology and Metabolism 2001;86:1620-1625.
Chiu KC, Martinez DS, Chu A: Comparison of the relationship of age and beta cell function in three ethnic groups. Clinical Endocrinology 2005;62:296-302.
Karnchanasorn R, Ou H-Y, Chuang L-M, Chiu KC: Insulin resistance is not an essential component for metabolic syndrome. Endocrine 2013;43:92–99.
City of Hope:
Karnchanasor R, Malamug LR, Jin R, Karanes C, Chiu KC: Association of hyperglycemia with prolonged hospital stay but has no effect on engraftment after autologous hematopoietic stem cell transplantation. Endocrine Practice 2012;18;508-518.
As a member of the Look AHEAD Research Group:
Williamson DA, et al. Look AHEAD Research Group: Impact of a weight management program on health-related quality of life in overweight adults with type 2 diabetes. Archive of Internal Medicine 2009;169:163-171.
Wadden TA, et al. Look AHEAD Research Group: One-year weight losses in the Look AHEAD study: factors associated with success. Obesity (Silver Spring). 2009;17:713-722.
Unick JL, et al. Look AHEAD Research Group. Effectiveness of lifestyle interventions for individuals with severe obesity and type 2 diabetes: results from the Look AHEAD trial. Diabetes Care 2011;34:2152-2157.
Schwartz AV, et al. Look AHEAD Research Group. Effect of 1 year of an intentional weight loss intervention on bone mineral density in type 2 diabetes: results from the Look AHEAD randomized trial. Journal of Bone and Mineral Research 2012;27:619-627.
Belalcazar LM, et al. Look AHEAD Research Group: Adiponectin and the mediation of HDLcholesterol change with improved lifestyle: the Look AHEAD Study. Journal of Lipid Research 2012;53:2726-2733.
This is a partial list. Full publications list available upon request. Information on this page may be self-reported and is subject to change at any time. Last updated: 01/13