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Nuclear hormone receptors
AccessScience@McGraw-Hill (online overview)
Detection of designer steroids
2005 Nuclear Receptor Signaling Vol. 3 doi:10.1621/nrs.03002
Are those phospholipids in your pocket?
2005 Cell Metabolism 15(5): 1311-1313.
Identification of an agonist ligand for estrogen-related receptors ERRß/?
2005 Bioorganic & Medicinal Chemistry Letters 15(5): 1311-1313.
Structure of the murine constitutive androstane receptor complexed to androstenol: a molecular basis for inverse agonism
2004 Molecular Cell 16(6):907-17.
Simple and efficient production of (Z)-4-hydroxytamoxifen, a potent estrogen receptor modulator
2003 J Organic Chemistry 68(24): 9489-9491.
Identification of an endogenous ligand that activates Pregnane X Receptor-mediated sterol clearance
2003 Proc Natl Acad Sci U S A 100 (3): 833-838.
Identification of gene-selective modulators of the bile acid receptor FXR
2002 The Journal of Biological Chemistry 278 (9): 7027-7033.
A structural model of the Constitutive Androstane Receptor (CAR) defines novel interactions that mediate ligand-independent activity
2002 Molecular and Cellular Biology 22 (15): 5270-5280.
The antidiabetic agent LG100754 sensitizes cells to low concentrations of PPAR? ligands
2002 The Journal of Biological Chemistry 277 (15): 12503-12506.
Peptide mimetic HIV protease inhibitors are ligands for the orphan receptor SXR
2001 The Journal of Biological Chemistry 276 (36): 33309-33312.
The orphan nuclear receptor SXR coordinately regulates drug metabolism & efflux
2001 Nature Medicine 7 (5): 584-590.
See accompanying News & Views.
Endogenous bile acids are ligands for the nuclear receptor FXR/BAR
1999 Molecular Cell 3 (5): 543-553.
See accompanying discussions in Cell and Science.
Androstane metabolites bind to and deactivate the nuclear receptor CARß
1998 Nature 395 (6702): 612-615.
See accompanying News & Views.
The orphan nuclear receptor LXRa is positively and negatively regulated by distinct products of mevalonate metabolism
1997 Proc Natl Acad Sci U S A 94 (20): 10588-10593.
Among the 50 Most-Frequently Cited PNAS Articles
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for PPARs a and d
1997 Proc Natl Acad Sci U S A 94(9): 4312-4317.
15-Deoxy-?12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR?
1995 Cell 83(5): 803-812.
Identification of a nuclear receptor that is activated by farnesol metabolites
1995 Cell 81(5): 687-693.
Unique response pathways are established by allosteric interactions among nuclear hormone receptors
1995 Cell 81(4): 541-550.
All recent articles (Medline)
This is a partial list. Full publications list available upon request. Information on this page may be self-reported and is subject to change at any time. Last updated: 06/08.