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 Selected Publications

Gaur, R.K. (2008). MicroRNA-mediated regulation of alternative splicing (submitted for publication, in Regulation of Gene expression by small RNAs. Eds R.K. Gaur and J.J. Rossi, Taylor & Francis, CRC Press, Boca Raton, Florida).

Dery, K.J., Gusti, V., Gaur, S., Shively, J.E., Yen, Y. and Gaur, R.K. (2008). Alternative splicing as a therapeutic target for human diseases. Methods in Mol. Med. (submitted).

Gaur, S., Shively, J.E., Yen, Y. and Gaur, R.K. (2008). Altered Splicing of CEACAM1 in Breast cancer: Identification of regulatory sequences that control splicing of CEACAM1 into long or short cytoplasmic domain isoforms. Molecular Cancer 7(1):46.

Gaur, R.K. (2008). T7 RNA polymerase mediated incorporation of 8-N3AMP into RNA for studying protein-RNA interactions. Methods Mol. Biol. (in press).

Gusti, V., Kim, D.S. and Gaur, R.K. (2008). Sequestering of the 3' splice site in a theophylline-responsive riboswitch allows ligand-dependent control of alternative splicing. Oligonucleotides 18, 93-99

Kim, D.S., Gusti, V., Dery, K.J. and Gaur, R.K. (2008). Ligand-induced sequestering of branchpoint sequence allows conditional control of Splicing. BMC Molecular Biology 9, 23.

Gaur, R.K. and Rossi, J.J. (2006). The diversity of RNAi and its applications. Biotechniques. Apr; Suppl:4-5.

Gaur, R.K. (2006) RNA interference: a potential therapeutic tool for silencing splice isoforms linked to human diseases. BioTechniques 40, 15-22.

Kim, D.S., Gusti, V., Dery, K.J. and Gaur, R.K. (2005). An artificial riboswitch for controlling pre-mRNA splicing. RNA 11, 1667-1677.

Gaur, R.K., Hanne, A. and Krupp, G. (2004) Combination of chemical and enzymatic RNA synthesis. Methods in Molecular Biology 252, 9-17.

Gopalakrishna, S., Gusti, V., Nair, S., Sahar, S. and Gaur R.K. (2004) Template-dependent incorporation of 8-N3AMP into RNA with bacteriophage T7 RNA polymerase. RNA 10, 1820-1830.

Gaur, R.K. and Krupp, G. (2000) A high throughput approach to identify nucleotide functional groups important in RNA structure and function. Ribozymes: Biochemistry and Biotechnology, 401-417. Eaton Publications, Natick, MA, USA.

Gaur, R.K., Beigelmen, L., Haeberli, P. and Maniatis, T. (2000) Role of adenine functional groups in the recognition of the 3’-splice site AG during the second step of pre-mRNA splicing. Proc. Natl. Acad. Sci. USA 97, 115-120.

Guth, S., Martinez, C., Gaur, R.K. and Valcárcel, J. (1999) Evidence for substrate-specific requirement of the splicing factor U2AF35and for its function after polypyrimidine tract recognition by U2AF65. Molecular and Cellular Biology 19, 8263-8271.

Gaur, R.K., McLaughlin, L.W. and Green, M.R. (1997) Functional group substitution of the branchpoint adenosine in a nuclear pre-mRNA and a group II intron. RNA 3, 861-869.

Gaur, R.K., Conrad, F. and Krupp, G. (1997) Applications of modified transcripts. Methods in Molecular Biology 74, 111-120.

Gaur, R.K. and Krupp, G. (1997). Preparation of templates for production of ribozymes and substrates. Methods in Molecular Biology 74, 69-78.

Gaur, R.K. & Krupp, G. (1997) Chemical and enzymatic approaches to construct modified RNAs. Methods in Molecular Biology 74, 99-110.

Gaur, R.K., Hanne, A., Conrad, F., Kahle, D. and Krupp, G. (1996) Differences in the interaction of E. coli RNase P RNA with tRNAs containing a short or a long extra arm. RNA 2, 674-681.

Valcárcel, J., Gaur, R.K., Singh, R. and Green, M.R. (1996) Interaction of U2AF65 RS region with pre-mRNA of branch point and promotion of base pairing with U2 snRNA. Science 273, 1706-1709.

Conrad, F., Hanne, A., Gaur, R.K. and Krupp, G. (1995). Enzymatic synthesis of 2'-modified nucleic acids: identification of important phosphate and ribose moieties in RNase P substrates. Nucleic Acids Res. 23, 1845-1853.

Gaur, R.K., Valcárcel, J. and Green, M.R. (1995) Sequential recognition of the pre-mRNA branch point by U2AF65and a novel spliceosome-associated 28-kDa protein.  RNA 1, 407-417.

Gaur, R.K., Sproat, B.S. and Krupp, G. (1992) Novel solid phase synthesis of 2'-O-methylribonucleoside 5'-triphosphates and their α thio analogues. Tetrahedron Lett. 33, 3301-3304.

Gaur, R.K. and Krupp, G. (1993) Enzymatic RNA synthesis with deoxynucleoside 5'-O-(1-thiotriphosphates). FEBS Letters 315, 56-60.

Gaur, R.K. and Krupp, G. (1993) Modification interference approach to detect ribose moieties important for optimal activity of a ribozyme. Nucleic Acids Res. 21, 21-26.

Gaur, R.K. (1991) High-performance liquid chromatography of synthetic oligonucleotides: A new affinity protecting group. J. of Chromatography 549, 207-215.

Gaur, R.K. (1991) Introduction of 5'-terminal amino and thiol groups into synthetic oligonucleotides. Nucleosides & Nucleotides 10, 895-909.

Gaur, R.K., Bobde, V., Atreyi, M. and Gupta, K.C. (1990) Synthesis of 9-fluorenylmethoxycarbonyl (Fmoc) exocyclic amino protected deoxynucleoside phosphoramidite for oligonucleotide synthesis. Ind. J. of chemistry 29B, 108-112.

Gaur, R.K. and Gupta, K.C. (1989) A simple method for the introduction of thiol group at the 5'-termini of oligodeoxynucleotides. Nucleic Acids Res. 17, 4404.

Gaur, R.K. and Gupta, K.C. (1989) A spectrophotometric method for the estimation of amino groups on polymer supports. Analytical Biochemistry 180, 253-258.

Gaur, R.K., Paliwal, S., Sharma, P. and Gupta, K.C. (1989) A simple and sensitive spectrophotometric method for the quantitative determination of solid supported amino groups. J. Biochem. Biophys. Methods 18, 323-330.

Gaur, R.K., Sharma, P. and Gupta, K.C. (1989). 4,4'-Dimethoxytrityl chloride: a reagent for the spectrophotometric determination of polymer supported amino groups. Analyst 114, 1147-1150.

Gaur, R.K. and Chauhan, V.S. (1988) Fatty acid derivatives of acidic amino acids as potential antibiotics. Ind. J. of chemistry 27B, 405-408.

This is a partial list. Full publications list available upon request. Information on this page may be self-reported and subject to change at any time. Last updated: 08/08

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