Wang, Y., Chen, W., Moore, D.D. and Huang, W. (2008) FXR, : not only a target for different diseasesa metabolic regulator and cell protector. Cell Res. (accepted)
Wang, Y., Yang, F., Chen, W., Huang, X., Lai, L., Forman, M.B., and Huang, W. (2008) Farnesoid X Receptor (FXR) Protects Liver Cells from Apoptosis Induced by Serum Deprivation in vitro and Fasting in vivo. Mol Endocrinol. (accepted)
Yang, F., Huang, X., Yi, T., Yen, Y., Moore, D. D., and Huang, W. (2007) Spontaneous development of liver tumors in the absence of the bile acid receptor Farnesoid X Receptor. Cancer Res. 67: 863-867.
Baskin-Bey, E., Huang, W., Ishimura, N., Bronk, S. F., Werneburg, N., Moore, D. D., and Gores, G. J. (2006) Constitutive androstane receptor (CAR) ligand, TCPOBOP, attenuates Fas-induced murine liver injury by altering Bcl-2 proteins. Hepatology. 44:252-262.
Huang, W., Ma, K., Zhang, J., Qatanani, M., Cuvillier, J., Liu, J., Dong, B., Huang X., and Moore D. D. (2006) Nuclear receptor dependent bile acid signaling is required for normal liver regeneration. Science (Article) 312:233-236.
Huang, W., Zhang, J., Washington, M., Liu, J., Parran, J., Lozano, G., and Moore D. D. (2005) Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor CAR. Mol Endocrinol. 19, 1646-1653.
Zhang, J., Huang, W., Qatanani, M., Evans, R., and Moore, D. D. (2004) The xenobiotic receptors CAR and PXR function coordinately to protect against bile acid-induced hepatotoxicity. J. Biol. Chem. 279, 49517-49522.
Huang, W., Zhang, J., Wei, P., Schrader, W. T., and Moore, D. D. (2004) Meclizine is an agonist ligand for mouse CAR and an inverse agonist for human CAR. Mol. Endocrinol. 18, 2402-2408
Huang, W., Zhang, J., and Moore D. D. (2004) A traditional herbal medicine enhances bilirubin clearance by activating the nuclear receptor CAR. J. Clin. Invest. 113, 137-143.
Huang, W., Zhang, J., Chua, S. S., Qatanani, M., Hang, Y., Granata, R., and Moore D. D. (2003) Induction of bilirubin clearance by the constitutive androstane receptor (CAR). Proc.Natl.Acad.Sci. USA 100, 4156-4161.
Zhang, J.*, Huang, W.*, Chua, S. S., Wei, P., and Moore D. D. (2002) Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR. Science 298, 422-424. (*: equal authority)
Huang, W., Lu, N., Eberspaecher, H. and de Crombrugghe, B. (2002) A new long form of c-Maf cooperates with SOX9 to activate the type II collagen gene. J. Biol. Chem. 277, 50668-50675.
Bi, W., Huang, W., Whitworth, D. J., Deng, J., Zhang, Z., Behringer, R. R. and de Crombrugghe, B. (2001). Haploinsufficiency of Sox9 results in defective precartilaginous mesenchymal condensations and premature skeletal mineralization. Proc.Natl.Acad.Sci. USA 98, 6698-6703.
Huang,W., Wang, S., Lozano,G. and de Crombrugghe, B. (2001). A new protocol of SOS recruitment system for library screening. BioTechniques 30, 94-100.
Huang, W., Chung, U., Kronenberg, H. M. and de Crombrugghe, B. (2001). The chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bones. Proc.Natl.Acad.Sci. USA 98, 160-165.
Huang,W., Zhou,X., Lefebvre, V. and de Crombrugghe, B. (2000). Phosphorylation of Sox9 by cyclic AMP dependent protein kinase A enhance its transcriptional activity on Col2al chondrocyte-specific enhancer. Mol.Cell.Biol. 20, 4149-4158.
Lefebvre, V., Huang, W., Harely. V. R., Goodfellow, P. N. and de Crombrugghe, B. (1997). Sox9 is a potent activator of the chondrocyte-specific enhancer of the Proal(ll) collagen gene. Mol.Cell.Biol. 17, 2336-2346.
This is a partial list. Full publications list available upon request. Information on this page may be self-reported and is subject to change at any time. Last updated: 04/08