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Video Time Lapse Microscopy (VTLM) demonstrates that SKI-606 (bosutinib) suppresses cell motility in MDA-MB-231 human breast cancer cells.

A

 

B

Wound healing assays were performed on MDA-MB-231 cells cultured in the presence of the DMSO control   Wound healing assays were performed on MDA-MB-231 cells cultured in the presence of 1 µM SKI-606

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Wound healing assays were performed on MDA-MB-231 cells cultured in the presence of the DMSO control (A) or 1 µM SKI-606 (B).  Photomicrographs were captured for a total of 50 h at 2 min intervals (10x magnification).

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