Tan Z, Wortman M, Dillehay KL, Seibel WL, Evelyn CR, Smith SJ, Malkas LH, Zheng Y, Lu S, Dong Z. Small - molecule targeting of proliferating cell nuclear antigen chromatin association inhibits tumor cell growth. Mol Pharmacol.. 2012 Jun;81(6):811-9. doi: 10.1124/mol.112.077735. Epub 2012 Mar. PMID: 22399488

Sandoval JV, Malkas LH, Hickey RJ. Clinical significance of serum biomarkers in pediatric solid medicastinal and abdominal tumors. Int J Mol Sci. 212;13(1):1126-53.doi: 10.3390/ijms13011126.Epub 2012 Jan 20. PMID: 22312308

Fei Shen, Kirmani Kashif Zubair, Zhimin Xiao, Thirlby Benjamin, Hickey, Robert and Malkas Linda. Nuclear protein isoforms: implications for cancer diagnosis and therapy.  J. Cell Biochemistry (2011) Mar;112(3):756-60. doi: 10.1002/jcb.23002

Wang X, Hickey RJ, Malkas LH, Koch MO, Li L, Zhang S, Sandusky GE, Grignon DJ, Eble JN, Cheng L. Elevated expression of cancer-associated proliferating cell nuclear antigen in high-grade prostatic intraepithelial neoplasia and prostate cancer. Prostate. 2010 Oct 28. [Epub ahead of print]PMID: 21031434

Snider BM, Phipps E, Smith SJ, Herbert BS, Hickey RJ, Malkas LH, (2009) DNA Replication: Mammalian. Encyclopedia of Life Sciences. John Wiley & Sons, Ltd: Chichester http://www.els.net/ [DOI: 10.1002/9780470015902.a0001041.pub2]

H Dai, J Liu, L Malkas and R Hickey.  (2009) Characterization of RNA primers synthesized by the human breast cancer cell DNA synthesome.  J. Cell Biochem. 106(5):798-811. (Featured article by journal).

Kyselova Z, Mechref Y, Kang P, Goetz JA, Dobrolecki LE, Sledge GW, Schnaper L, Hickey RJ, Malkas LM, Novotny MV.  Breast Cancer Diagnosis and Prognosis through Quantitative Measurements of Serum Glycan Profiles.  (2008) Clin Chem 54(7):1166-75.

Linda H. Malkas, Brittney-Shea Herbert, Waleed Abdel-Aziz, Lacey E. Dobrolecki, Yang Liu, Beamon Agarwal, Derek Hoelz, Sunil Badve, Lauren Schnaper, Randy J. Arnold, Yehia Mechref, Milos V. Novotny, Patrick Loehrer, Robert J. Goulet, and Robert J. Hickey. (2006) A cancer-associated PCNA expressed in breast cancer has implications as a potential biomarker. Proc. Natl. Acad. Sci. U.S.A. 103(51):19472-19477.

Derek Hoelz, Randy Arnold, Lacey Dobrolecki, Waleed Abdel-Aziz, Andrew Loehrer, Milos Novotny, Lauren Schnaper, Robert Hickey, and Linda Malkas. Discovery of Labile Methyl Esters on Proliferating Cell Nuclear Antigen by Mass Spectrometry Peptide Mapping.  (2006) Proteomics 6(7):4808-4816.

Tanaka, H., M. Mendonca, P. Bradshaw, D. Hoelz, L. Malkas, M. Meyn, and D. Gilley (2005) DNA damage induced phosphorylation of the human telomere-associated protein TRF2. Proc. Natl. Acad. Sci. U.S.A. 102 (43): 15539-15544.

Jin Yang, Zhiwen Chen, Yang Liu, Robert J. Hickey, and Linda H. Malkas, Altered DNA Polymerase iota expression in Breast Cancer Cells Leads to a Reduction in DNA Replication Fidelity and a Higher Rate of Mutagenesis, (2004) Cancer Research 64: 5597-5607.

P. M. Vertino, J. A. Sekowski, J. M. Coll, N. Applegren, S. Han, and L. H. Malkas, DNMT1 Is a Component of a Multiprotein DNA Replication Complex. (2002) Cell Cycle 6:416-423.

H.-Y. Jiang, W. Abdel-Aziz, T. Tom, R. Hickey, P. Wills, J. Liu and L. H. Malkas, Human Cell DNA Replication Is Mediated by a Discrete Multiprotein Complex. (2002) J. Cell Biochem 85: 762-774.

D. Strumberg, A.A. Pilon, M. Smith, R. Hickey, L. Malkas, and Y. Pommier, Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5’-phosphorylated DNA double-stranded breaks by replication runoff.   (2000) Molecular and Cellular Biology 20: 3977-3987.

P.E. Bechtel, R.J. Hickey, L. Schnaper, J.W. Sekowski, B.J. Long, R. Freund, N. Liu, C. Rodriguez-Valenzuela and L.H. Malkas, A Unique Form of Proliferating Cell Nuclear Antigen Is Present in Malignant Breast Cells.   (1998) Cancer Research 58: 3264-3269.

J.W. Sekowski, L.H. Malkas, L. Schnaper, P.E. Bechtel, B.J. Long and R.J. Hickey, Human Breast Cancer Cells Contain an Error-prone DNA Replication Apparatus.  (1998) Cancer Research 58: 3259-3263.

L.H. Malkas, R.J. Hickey, C.J. Li, and E.F. Baril, A 21S enzyme complex from HeLa cells that functions in Simian Virus 40 DNA replication in vitro.  Isolation, purification and characterization of its physical and catalytic properties. (1990) Biochemistry 29: 6362-6374.


This is a partial list. Full publications list available upon request. Information on this page may be self-reported and is subject to change at any time. Last updated: 03/13.