Putta S, Lanting L, Sun G, Lawson G, Kato M and Natarajan R . Inhibiting MicroRNA-192 Ameliorates Renal Fibrosis in Diabetic Nephropathy (2012. J. Am. Soc. Nephrol. 2012 Mar;23(3):458-69

Kato M, Arce L,  Wang M, Putta S, Lanting L, and Natarajan R. (2011) A microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cells.  Kidney International 2011 Aug;80(4):358-68 (Comment in the same issue of Kid Intl pg 334-337)

Jin F, Li Y, Ren B, Natarajan R. (2011) PU.1 and C/EBPa synergistically program distinct response to NF-κB activation through establishing monocyte-specific enhancers. Proc. Natl Acad. Sci USA. 108 (13): 5290-5295. PMID: 21402921; PubMed Central PMCID: PMC3069155

Reddy MA and Natarajan R. Epigenetics in Diabetic Renal Disease. (2011) Science in Renal Medicine Series. J. Am Soc. Nephrol. (In Press) 2011 Oct 21. [Epub ahead of print

Meng L*, Park J*, Cai Q*, Lanting L, Reddy MA and Natarajan R. (2010) Diabetic Conditions Promote Binding of Monocytes to Vascular Smooth Muscle Cells and their Subsequent Differentiation. Am. J. Physiol. Heart Circ Physiol. 298(3):H736-45. (*equal contribution) (Editorial in same issue, H731)

Villeneuve LM, Kato M, Wang M, Reddy MA, Lanting L, Natarajan R. (2010). Enhanced microRNAs-125b levels in vascular smooth muscle cells of diabetic mice leads to increased inflammatory gene expression by targeting the histone methyltransferase Suv39h1. Diabetes. 59(11):2904-15.

Villenueve LM and Natarajan R. (2010) The Role of Epigenetics in the Pathology of Diabetic Complications. American Journal of Physiology, Renal. 299: F14–F25, 2010.

Kato M, Wang L, Putta S, Wang M, Yuan H, Sun G, Lanting L, Todorov I, Rossi JJ, and Natarajan R. (2010). Post-transcriptional upregulation  of Tsc-22 by Ybx1, a target of miR-216a, mediates TGF-β –induced collagen expression in renal cells. J.Biol.Chem. 285(44):34004-15.  Paper of the Week - top 1% of papers.

Sun G, Reddy MA, Yuan H, Lanting L, Kato M, and Natarajan R. 2010. Epigenetic histone methylation modulatesfibrotic gene expression in mesangial cells.J. Am. Soc. Nephrol. 21(12):2069-80 (PMCID: 3014020)

Kato M, Wang M, Yuan H, Lanting L, Putta P, Gunn A, Nakagawa Y, Shimano H, Rossi JJ and Natarajan R. (2009) TGF-beta activates Akt kinase via a microRNA-dependent amplifying circuit argeting PTEN. Nature Cell Biology  11:881-889. (Faculty of 1000)

Villeneuve LM, Reddy MA, Lanting L, Wang M, Meng L, Natarajan R. (2008) Epigenetic Histone H3 Lysine  9 Methylation in Metabolic Memory and Inflammatory Phenotype of Vascular Smooth Muscle Cells in Diabetes. Proc. Natl Acad Sci USA 105(26):9047-52.

Yuan H, Lanting L, Xu ZG, Wang M, Li SL, Swiderski P, Putta S, Jonnalagadda M, , Kato M and Natarajan R. (2008) Effects of Cholesterol tagged short interfering RNAs targeting 12/15-lipoxygenase on parameters of diabetic nephropathy in a mouse model of type 1 diabetes. Am. J. Physiol. (Renal)  295(2):F605-F617.

Li Y, Reddy MA, Miao F, Shanmugam N, Yee JK, Hawkins D, Ren B, Natarajan R. (2008) Role of the histone lysine methyltransferase SET7/9 in the regulation of NF-kB-dependent inflammatory genes. J. Biol. Chem. 283:26771-26781.

Miao F, David D. Smith†, Lingxiao Zhang*, Andrew Min*, Wei Feng*, Natarajan R. (2008)   Lymphocytes from Patients with Type 1 diabetes Reveal a Distinct Profile of Chromatin Histone H3  Lysine 9 Dimethylation: An Epigenetic Study in Diabetes. Diabetes. 57:3189-3198. Commentary in the same issue on page 3184 by Litherland SA

Shanmugam N, Reddy MA, Natarajan R. (2008) Distinct Roles of hnRNPK and microRNA-16 in S100b Induced Cyclooxygenase-2 mRNA Stability in Monocytes. J. Biol.Chem, 283(52):36221-33. Paper of the Week . Comment in the same issue.

Xu Z-G*, Yuan H* , Lanting L, Li SL, Wang M, Shanmugam N, Kato M, Adler SG, Reddy MA,  Natarajan R. (2008). Regulation of Angiotensin II Type 1 Receptor Expression by 12/15- Lipoxygenase Pathway Activation in Mesangial Cells. J. Am Soc. Nephrol. 19: 559–569, 2008

Kato M, Zhang J, Wang M, Yuan H, Rossi JJ, Natarajan R. (2007) MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors. Proc. Natl. Acad. Sci. USA. 104:3432-3437

This is a partial list. Full publications list available upon request. Information on this page may be self-reported and is subject to change at any time. Last updated: 03/12