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 Selected Publications

Zhang, J., Liu, L., and Pfeifer, G.P. (2004) Methylation of the retinoid response gene TIG1 in prostate cancer correlates with methylation of the retinoic acid receptor beta gene, Oncogene 23, 2241-2249.

Szabó, P.E., Pfeifer, G.P., and Mann, J.R. (2004) Parent of origin-specific binding of nuclear hormone receptor complexes in the H19/Igf2 imprinting control region, Mol. Cell. Biol. 24, 4858-4868.

Besaratinia, A., and Pfeifer, G.P. (2004) Genotoxicity of acrylamide and glycidamide, J. Natl. Cancer Inst 96, 1023-1029.

Yoon, J.-H., Besaratinia, A., Feng, Z., Tang, M.-s., Amin, A., Luch, A., and Pfeifer, G.P. (2004) DNA damage, repair and mutation induction by (+)-syn and (–)-anti-dibenzo[a,l]pyrene-11,12-diol-13,14-epoxides in mouse cells, Cancer Res. 64, 7321-7328.

Jiang, C.L., Jin, S.G., and Pfeifer, G.P. (2004). MBD3L1 Is a Transcriptional Repressor That Interacts with Methyl-CpG-binding Protein 2 (MBD2) and Components of the NuRD Complex. J. Biol. Chem. 279, 52456-52464.

Tommasi, S.,  Dammann, R.,  Zhang, Z., Wang, Y., Liu, L., Tsark, W., Wilczynski, S., Li, J., You, M., and Pfeifer, G.P. (2005) Tumor susceptibility of Rassf1a knockout mice, Cancer Res. 65, 91-98.

Jin, S.-G.,  Jiang, C.-L., Rauch, T., Li, H., and Pfeifer, G.P. (2005) MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2/MeCP1-mediated methylation silencing, J. Biol. Chem. 280, 12700-12709.

Baksh, S., Tommasi, S., Fenton, S., Yu, V.C., Martins, L.M., Pfeifer, G.P., Latif, F., Downward, J., and Neel, B.G. (2005) The tumor suppressor RASSF1A and MAP-1 link death receptor signaling to BAX conformational change and cell death, Mol. Cell 18, 637-650.

Besaratinia, A., Synold, T.W., Chen, H.H., Chang, C., Xi, B., Riggs, A.D., and Pfeifer, G.P. (2005) DNA lesions induced by UV A1 and B radiation in human cells: comparative analysesin the overall genome and in the p53 tumor suppressor gene, Proc. Natl. Acad. Sci. USA 102, 10058-10063.

Rauch, T., and Pfeifer, G.P. (2005) Methylated-CpG island recovery assay (MIRA): a new technique for the rapid detection of methylated CpG islands in cancer, Lab. Invest. 85, 1172-1180.

Lee, D.-H., Jin, S.-G., Cai, S., Chen, Y., Pfeifer, G.P., and O'Connor, T.R., Repair of methylation damage in DNA and RNA by mammalian AlkB homologues, J. Biol. Chem. 280, 39448-39459.

Yoon, J.-H., Singh, P., Lee, D.-H., Qiu, J., Cai, S., O'Connor, T.R., Chen, Y., Shen, B., and Pfeifer, G.P. (2005) Characterization of the 3’ to 5’ exonuclease activity found in human nucleoside diphosphate kinase 1 (NDK1) and several of its homologues, Biochemistry 44, 15774-15786.

Yoon, J.-H., Qiu, J., Cai, S., Chen, Y., Cheetham, M.E., Shen, B., and Pfeifer, G.P. (2006) The retinitis pigmentosa-mutated RP2 protein exhibits exonuclease activity and translocates to the nucleus in response to DNA damage, Exp. Cell Res 312, 1323-2434..

Pfeifer, G.P.  (2006) Mutagenesis at methylated CpG sequences, Curr. Topics Microbiol. Immunol. 301, 259-281.

Li, H, Rauch, T., Chen, Z.-X., Szabo, P.E., Riggs, A.D., and Pfeifer, G.P. (2006) The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells, J. Biol. Chem. 281, 19489-19500.

Rauch, T., Li, H., Wu, X., and Pfeifer, G.P. (2006) MIRA-assisted microarray analysis, a new technology platform for the determination of genome-wide DNA methylation patterns,  identifies frequent methylation of homeodomain containing genes in lung cancer cells, Cancer Res., in press.

This is a partial list. Full publications list available upon request. Information on this page may be self-reported and subject to change at any time. Last updated 06/08.

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