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 Selected Publications

Huberman, J. A. & Riggs, A.D. (1968)  On the mechanisms of DNA replication  in mammalian chromosomes.  J. Mol. Biol. 32:327-341.

Riggs, A.D. & Bourgeois, S. (1968)  On the assay, isolation, and characterization of the lac repressor. J. Mol. Biol. 34:36l-364.

Riggs, A.D. (1975)   X inactivation, differentiation, and DNA methylation.  Cytogenet. Cell Genet.
14:9-25.

Goeddel, D.V., Kleid, D.G., Bolivar, F., Heyneker, H.L., Yansura, D.G.,  Crea, R., Hirose, Kraszewski, A., Itakura, K., & Riggs, A.D.,  (1979)  Expression in E. coli of chemically synthesized genes for human insulin.  Proc. Natl. Acad. Sci. USA 76:106-110.

Riggs, A.D. & Jones, P.A.  (1983)  Methylcytosine, gene regulation, and cancer.  Adv. Cancer Res. 40: 1-30.

Cabilly, S., Riggs, A.D., Pande, H., Shively, J.E., Holmes, W., Wetzel, R.,  & Heyneker, H.  (1984)  Generation of antibody activity from immunoglobulin  peptide chains produced by E.coli.  Proc. Natl. Acad. Sci. USA  81:3273-3277.

Pfeifer, G.P., Tanguay, R.L., Steigerwald, S.D., and Riggs, A.D. (1990)  In vivo footprint and methylation analysis by genomic sequencing: comparison of active and inactive X chromosomal DNA at the CpG island and promoter of human PGK-1.  Genes and Development  4:1277-1287.

Tagoh, H., Melnik, S., Lefevre, P., Chong, S., Riggs, A.D., and Bonifer, C. (2004) Dynamic reorganization of chromatin structure and selective DNA-demethylation prior to stable enhancer complex formation during differentiation of primary hematopoietic cells in vitro.  Blood 103:2950-2955

Riggs, A.D., and Xiong, Z. (2004) Methylation and epigenetic fidelity.  Proc. Nat. Acad. Sci. USA, 101: 4-5

Chen H.H., Castanotto D, LeBon J., Rossi J.J., Riggs A.D. (2004) In vivo detection of ribozyme cleavage products and RNA structure by use of terminal transferase-dependent PCR. Methods Mol Biol. 252:109-124.

Ingram, R., Tagoh, H., Riggs, A.D., and Bonifer, C. (2005) Rapid, solid-phase based automated analysis of chromatin structure and transcription factor occupancy in living eukaryotic cells. Nucleic Acids Res. 33:e1.

Chen, Z.X., and Riggs, A.D. (2005)  Maintenance and Regulation of DNA Methylation Patterns in Mammals. Biochem Cell Biol. 83:438-448

Weinberg, M.S., Villeneuve, L.M., Ehsani, A., Amarzguioui, M., Aagaard, L., Chen, Z.X., Riggs, A.D., Rossi, J.J., and  Morris, K.V. (2006)  The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells.  RNA 12:256-262

Shen Y, Matsuno Y, Fouse SD, Rao N, Root S, Xu R, Pellegrini M, Riggs AD, Fan G (2008) X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations.  Proc. Natl. Acad. Sci. U. S. A. 105:4709-14.

Rauch TA, Zhong X, Wu X, Wang M, Kernstine KH, Wang Z, Riggs AD, Pfeifer GP. (2008) High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer. Proc Natl. Acad. Sci. U. S. A. 105:252-7

Branciamore S, Chen ZX, Riggs AD, Rodin SN. CpG Island clusters and pro-epigenetic selection for CpGs in protein coding exons of Hox and other transcription factors. Proc. Natl. Acad. Sci. U. S. A.  In submission. Click hyperlink to see Human Genome CPGnorm Coding Reagion Data  [supplement]

This is a partial list. Full publications list available upon request. Information on this page may be self-reported. Last updated 07/10.

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