Kirshner, J., Chen, C-J., Liu, P., Huang, J., and Shively, J.E. CEACAM1-4S, a cell-cell adhesion molecule, mediates apoptosis and reverts mammary carcinoma cells to a normal phenotype in a 3D culture. Proc Natl Acad Sci USA. 100: 521-526, 2003.
Kirshner, J., Schumann, D., Shively, J.E. CEACAM1, a cell-cell adhesion molecule, directly associates with annexin II in a three-dimensional model of mammary morphogenesis. J Biol Chem 278: 50338-50345, 2003.
Wong, J.Y., Shibata, S., Williams, L.E., Kwok, C.S., Liu, A., Chu, D.Z., Yamauchi, D.M., Wilczynski, S., Ikle, D.N., Wu, A.M., Yazaki, P.J., Shively, J.E., Doroshow, J.H., Raubitschek, A.A. A Phase I trial of 90Y-anti-carcinoembryonic antigen chimeric T84.66 radioimmunotherapy with 5-fluorouracil in patients with metastatic colorectal cancer. Clin Cancer Res 9: 5842-5852, 2003.
Sundaresan, G., Yazaki, P.J., Shively, J.E., Finn, R.D., Larson, S.M., Raubitschek, A.A., Williams, L.E., Chatziioannou, A.F., Gambhir, S.S., Wu, A.M. 124I-labeled engineered anti-CEA minibodies and diabodies allow high-contrast, antigen-specific small-animal PET imaging of xenografts in athymic mice. J Nucl Med 44: 1962-1969, 2003.
Carmichael, J.A., Power, B.E., Garrett, T.P., Yazaki, P.J., Shively, J.E., Raubitschek, A.A., Wu, A.M., Hudson, P.J. The crystal structure of an anti-CEA scFv diabody assembled from T84.66 scFvs in V(L)-to-V(H) orientation: implications for diabody flexibility. J Mol Biol 326: 341-351, 2003.
Reeve Jr JR, Liddle RA, McVey DC, Vigna SR, Solomon TE, Keire DA, Rosenquist G, Shively JE, Lee TD, Chew P, Green GM, Coskun T. Identification of non-sulfated cholecystokinin-58 in canine intestinal extracts and its biological properties. Am J Physiol Gastrointest Liver Physiol., 287: G326-G333, 2003.
Guo, G., Wang, T., Gao, Q., Tamae, D., Wong, P., Chen, T., Chen, W.C., Shively, J.E., Wong, J.Y., Li, J.J. Expression of ErbB2 enhances radiation-induced NF-kappaB activation. Oncogene 23: 535-545, 2004.
Olavsen, T., Cheung, C-w., Yazaki, P.J., Li, L., Sundaresan, G., Gambhir, S.S.,Sherman, M.A., Williams, L.E., Shively, J.E., Raubitschek, A.A., and Wu, A.M. Covalent disulfide linked anti-CEA diabody allows site-specific conjugation and radiolabeling for tumor targeting applications. Prot Eng Design Sel 17: 1-7, 2004.
Schumann D, Huang J, Clarke PE, Kirshner J, Tsai SW, Schumaker VN, Shively JE. Characterization of recombinant soluble carcinoembryonic antigen cell adhesion molecule 1. Biochem Biophys Res Commun 318: 227-233, 2004.
Chen, C.J., and Shively, J.E. The cell-cell adhesion molecule carcinoembryonic antigen related cellular adhesion molecule 1 inhibits IL-2 prooduction and proliferation in human T-cells by association with Src homology protein-1 and down regulates IL-2 receptor. J Immunol 172: 3544–3552, 2004.
Kirshner, J., J. Hardy, S. Wilczynski, and Shively, J.E. Cell-cell adhesion molecule CEACAM1 is expressed in normal breast and milk and associates with beta1 integrin in a 3D model of morphogenesis. J Mol Histol 35: 287-299, 2004.
Shively JE. CEACAM1 and hyperplastic polyps: new links in the chain of events leading to colon cancer. Oncogene. 23: 9303-9305, 2004.
Yazaki PJ, Sherman MA, Shively JE, Ikle D, Williams LE, Wong JY, Colcher D, Wu AM, Raubitschek AA. Humanization of the anti-CEA T84.66 antibody based on crystal structure data. Protein Eng Des Sel. 17: 481-489. 2004.
Olafsen T, Tan GJ, Cheung CW, Yazaki PJ, Park JM, Shively JE, Williams LE, Raubitschek AA, Press MF, Wu AM. Characterization of engineered anti-p185HER-2 (scFv-CH3)2 antibody fragments (minibodies) for tumor targeting. Protein Eng Des Sel. 17: 315-23, 2004.
Wilczynski SP, Chen YY, Chen W, Howell SB, Shively JE, Alberts DS. Expression and mutational analysis of tyrosine kinase receptors c-kit, PDGFRalpha, and PDGFRbeta in ovarian cancers. Hum Pathol. 36: 242-249, 2005.
Kenanova V, Olafsen T, Crow DM, Sundaresan G, Subbarayan M, Carter NH, Ikle DN, Yazaki PJ, Chatziioannou AF, Gambhir SS, Williams LE, Shively JE, Colcher D, Raubitschek AA, Wu AM. Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments. Cancer Res. 65: 622-631, 2005.
Olafsen, T., Kenanova, V. E., Sundaresan, G., Anderson, A. L., Crow, D., Yazaki, P. J., Li, L., Press, M. F., Gambhir, S. S., Williams, L. E., Wong, J. Y., Raubitschek, A. A., Shively, J. E., Wu, A. M. Optimizing radiolabeled engineered anti-p185HER2 antibody fragments for in vivo imaging. Cancer Res. 65: 5907-5916, 2005.
This is a partial list. Full publications list available upon request. Information on this page may be self-reported and is subject to change at any time. Last updated: 03/07.
