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 Selected Publications

Thomas J, Austin Cooney G, Slatkin N. Palliative Care and Pain: New Strategies for Managing Opioid Bowel Dysfunction. Journal of Palliative Medicine, (2008) 11(S1) S1-24.

Elia G, Thomas J. The Symptomatic Relief of Dyspnea. Current Oncology Reports (2008) 10(4): 319-325.

Thomas J*, Karver S*, MD, Austin Cooney G, Chamberlain BF, Watt CK, Slatkin NE, Stambler N, Kremer AB, Israel RJ. Methylnaltrexone for Opioid-Induced Constipation in Advanced Illness. New England Journal of Medicine, (2008) 358(22): 2332-2343. (* denotes equal contribution)

Portenoy RK, Thomas J, Moehl Boatwright ML, Tran D, Galasso FL, Stambler N, von Gunten CF, Israel RJ. Subcutaneous Methylnaltrexone for the Treatment of Opioid-Induced Constipation in Patients with Advanced Illness: A Double-Blind, Randomized, Parallel Group, Dose-Ranging Study. Journal of Pain and Symptom Management, (2008) 35(5): 458-468.

Thomas, J. Opioid-Induced Bowel Dysfunction, Journal of Pain & Symptom Management, (2007) 35(1): 103-113.

Thomas JR, Yocum RC, Haller MF, von Gunten CF. Assessing the Role of Human Recombinant Hyaluronidase in Gravity-Driven Subcutaneous Hydration: The INFUSE-LR Study. Journal of Palliative Medicine, (2007) 10(6): 1312-1320.

Thomas J. Cancer-related Constipation, Current Oncology Reports, (2007) 9(4): 278-284.

Thomas JR, von Gunten CF. Diagnosis and Management of Ascites, Principles and Practices of Palliative Care and Supportive Oncology (2007) A.M. Berger, J. L. Shuster, and J. H. Von Roenn, Eds., Lippincott Williams & Wilkins, Chapter 17, p. 185-191.

Thomas J, von Gunten CF. Dyspnea, Textbook of Palliative Medicine (2006) E. Bruera, I. Higginson, C. Ripamonti, C. von Gunten, Eds., Edward Arnold (Publishers) Ltd., Chapter 69, p. 655-662.

Thomas J, von Gunten CF. Pharmacologic therapies for pain, Current Diagnosis & Treatment: Pain (2006) J. von Roenn, J. Paice, M. Preodor, Eds., Lange Medical Books/McGraw-Hill, Chapter 3, p. 21-37.

Thomas J, von Gunten CF. Pharmacologic therapies for pain, Current Diagnosis & Treatment: Pain (2006) J. von Roenn, J. Paice, M. Preodor, Eds., Lange Medical Books/McGraw-Hill, Chapter 3, p. 21-37.

Thomas J. What options exist for relieving opioid-induced constipation. Cure, (2006) 5(2): 19.

Thomas J. Strategies to Manage Constipation. Journal of Supportive Oncology, (2006) 4(5): 220-223.

Slatkin N, Karver S, Thomas J, Chamberlain B, Austin–Cooney G, Watt C, Winston J, Cross K, McGrew D, Stambler N, Israel RJ. A Phase III Double-Blind, Placebo-Controlled Trial of Every Other Day Dosing of Methylnaltrexone for Opioid-Induced Constipation in Advanced Illness. Gastroenterology, (2006) 131(3): 950.

Thomas J, Lipman A, Slatkin N, Wilson G, Moehl M, Wellman C, Zhukovsky D, Stephenson R, Stambler N, Israel R. A phase III double-blind, placebo-controlled trial of methylnaltrexone (MNTX) for opioid-induced constipation (OIC) in advanced medical illness (AMI). Journal of Clinical Oncology, (2005) 23(16S): 1096s.

Thomas JR, von Gunten CF. Management of Constipation in Patients with Cancer, Supportive Cancer Therapy (2004) 2(1): 47-51.

Thomas JR, Kronenberg R, Cox MC, Naco GC Wallace M, and von Gunten CF. Intravenous lidocaine relieves severe pain: Results of an inpatient hospice chart review. Journal of Palliative Medicine (2004) 7(5): 660-667.

Thomas JR, von Gunten CF. Opioids for Dyspnea: What is the Evidence?. In: AAHPM Bulletin. Paul Rousseau, Ed., (2004) 5(3): 5-6.

Thomas JR, Ferris FD, von Gunten CF. Approach to Management of Cancer pain. In: Essentials of Pain Medicine and Regional Anesthesia. (2004) Honorio T. Benzon, MD, Srinivasa N. Raja, MD, Robert E. Molloy, MD, Spencer Liu, MD, Scott M. Fishman, MD, Eds. 2nd Edition Elsevier Science, New York, Chapter 63, p. 525-534.

Bowen K, Thomas JR, von Gunten CF. The Management of Ascites, Palliative Care Consultations in Gynaecology (2004) S. Booth, E Bruera, Eds., Oxford University Press, Chapter 10, p. 133-142.

Thomas JR, von Gunten CF. Peer Viewpoint: Clinical Status of Methylnaltrexone, A New Agent to Prevent and Manage Opioid-Induced Side Effects, Journal of Supportive Oncology (2004) 2(2): 119-121.

Thomas JR, von Gunten CF. Management of Dyspnea, Journal of Supportive Oncology (2003) 1(1): 23-32.

Thomas JR, von Gunten CF. Pain in Terminally Ill Patients, Guidelines for Pharmacological Management, CNS Drugs (2003) 17(9): 621-631.

Thomas JR, von Gunten CF. Treatment of Dyspnea in Cancer Patients, Oncology (2002) 16(6): 745-750.

Thomas JR, von Gunten CF. Diagnosis and Management of Ascites, Principles and Practices of Palliative Care and Supportive Oncology (2002) A.M. Berger, R.K. Portenoy, and D.E. Weissman, Eds., Lippincott Williams & Wilkins, Chapter 17, p. 264-270.

Thomas JR, von Gunten CF. Clinical Management of Dyspnea, Lancet Oncology  (2002) 3(4): 223-228.

Starr DB, Matsui W, Thomas JR, Yamamoto KR. Intracellular receptors use a common mechanism to interpret signaling information at response elements, Genes and Development  (1996) 10(10): 1271-1283.

Thomas JR*, Lefstin JA*, Yamamoto KR. Influence of a steroid receptor DNA-binding domain on transcriptional regulatory functions, Genes & Development (1994)  8: 2842-2856. (* denotes equal contribution)

Garabedian MJ, LaBaer J, Lui W, Thomas JR. Analysis of protein-DNA interactions, Gene Transcription: A Practical Approach (1993) B.D. Hames and S.J. Higgins, Eds., IRL Press, p.  243-293.

Yamamoto KR, Pearce D, Thomas JR, Miner JN. Combinatorial Regulation at a Mammalian Composite Response Element, Transcriptional Regulation (1992) S. L. McKnight and K.R. Yamamoto, Eds., Cold Spring Harbor Laboratory Press, p. 1169-1192. 

This is a partial list. Full publications list available upon request. Information on this page may be self-reported and is subject to change at any time. Last updated: 09/08.

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