Qian S, Somlo G, Zhou BS, Mi S, Mo X, Cheung GM, Lian RJ, Rossi J, Holtz M, Chu P, Yen Y. Ribozyme-mediated down-regulation of fibroblast growth factor receptor 3 inhibits cell growth of human multiple myeloma and is associated with down-regulation of vascular endothelial growth factor. Oligoneucleotide, 15:1-11, 2005.
Chu PG, Schwarz RE, Lau SK, Yen Y, Weiss LM. Immunohistochemical staining in the diagnosis of pancreatobiliary and ampulla of Vater adenocarcinoma: application of CDX2, CK17, MUC1, and MUC2. Am J Surg Pathol, 29(3):359-367, 2005.
Zhu LJ, Somlo G, Zhou BS, Shao J, Bedell V, Slovak ML, Liu XY, Lou JH, Yen Y. Short-hairpin RNAs inhibit fibroblast growth factor receptor 3 inhibition by short hairpin RNAs leads to apoptosis in multiple myeloma. Molecular Cancer Therapeutics, 4:787-798, 2005.
Yen Y. Growth arrest damage-inducible gene 45β in human liver cancer. Handbook of Immunohistochemistry and in situ hybridization of Human Carcinomas , second version, 3:207-216, 2005.
Qiu WH, Zhou BS, Chu PG, Chen WG, Chung C, Shih J, Hwu P, Yeh C, Lopez R, Yen Y. Over-expression of fibroblast growth factor receptor 3 in human hepatocellular carcinoma. World J Gastroenterol, 11(34);5266-5272, 2005.
Liu X, Zhou B, Xue, L, Shih J, Tye K, Qi Ch, Yen Y. The ribonucleotide reductase subunit M2B subcellular localization and functional importance for DNA replication in physiological growth of KB cells. Biochem Pharm, 70: 1288-1297, 2005.
Boo L-M, Lin HH, Chung V, Zhou BS, Louie SG, O’Reilly MA, Yen Y, Ann DK. HMGA2 potentiates genotoxic stress in part through the modulation of basal and DNA damage-dependent phosphatidylinositol 3-kinase (Pi 3-K)-related protein Kinase activation. Cancer Research, 65:6622-6630, 2005.
Morgan RJ Jr, Synold TW, Gandara D, Muggia F, Scudder S, Reed E, Margolin K, Raschko J, Leong L, Shibata S, Tetef M, Vasilev S, McGonigle K, Longmate J, Yen Y, Chow W, Somlo, G, Carroll M, Doroshow JH. Phase I trial of topotecan, carboplatin, and topotecan in the treatment of recurrent or refractory brain or spinal cord tumors. In press, Neuro-Oncol, 2005.
Cao M-Y, Benatar T, Lee Y, Young AH, Yen Y, Wright JA. Recent Progress in Cancer Gene Therapy Chapter. In press, 2005.
Wang T, Tamae D, Lebon T, Shively JE, Yen Y, Li JJ. The role of peroxiredoxin II in radiation-resistant MCF-7 breast cancer cells. Cancer Research, 65(22):10338-10346, 2005.
Huang MJ, Lim KH, Tzen CY, Hsu HS, Yen Y, Huang BS. FGFR mutations in malignant pleural effusion of non-small cell lung cancer: a case report. Lung Cancer, 49(3): 413-415, 2005.
Qiu W, Zhou B, Darwish D, Shao J, Yen Y. Characterization of enzymatic properties of human ribonucleotide reductase holoenzyme reconstituted in vitro from hRRM1, hRRM2, and p53R2 subunits. Biochem and Biophys Res Comm, 340(2): 428-434, 2006.
Xue L, Zhou B, Liu X, Wang T, Shih J, Qi C, Heung Y, Yen Y. Structurally Dependent Redox Property of Ribonucleotide Reductase Subunit p53R2. Cancer Research, 66: 1900-1905, 2006.
Shao J, Zhou B, Di Bilio A, Zhu L, Wang T, Qi C, Shih J, Yen Y. A Ferrous-Triapine Complex Mediates Formation of Reactive Oxygen Species That Inactivate Human Ribonucleotide Reductase. Mol Can Ther, 5(3), 586-592, 2006.
Chung V, Zhou B, Liu X, Zhu L, Boo LM, Nguyen H-V, Ann DK, Song J, Chen Y, Yen Y. SUMOylation plays a role in gemcitabine- and bortezomib-induced cytotoxicity in human oropharyngeal carcinoma KB gemcitabine-resistant clone. Mol Can Ther, 5(3), 533-540, 2006.
Zhou B, Shao J, Su L, Yuan Y-C, Qi C, Shih J, Xi B, Chu B, Yen Y. A dityrosyl-diiron radical cofactor center is essential for human ribonucleotide reductases. Mol Can Ther, 4(12), 1830-1836, 2005-2006.
Un, F, Qi C, Prosser M, Wang N, Zhou B, Bronner C, Yen Y. Modulating ICBP90 to Suppress Human Ribonucleotide Reductase M2 Induction Restores Sensitivity to Hydroxyurea Cytotoxicity. Anticancer Res, 26(4), 2761–2768, 2006.
Shao J, Zhou B, Chu B, Yen Y. Ribonucleotide Reductase Inhibitors and Future Drug Design. Current Cancer Drug Targets 6, 409-431, 2006
Zhu L, Yen Y, Shao J, Qi CH, Yen, C Luo J, Zhou B. Fibroblast growth factor Receptor 3 up-regulates vascular endothelial growth factor expression in L6 cells. Intl Journal of Pharmacology, 2 (3): 324-330, 2006.
This is a partial list. Full publications list available upon request. Last updated: 07/08.
