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 Selected Publications

Yu H*, Pardoll D* and Jove* R. 2009  STATs in Cancer Inflammation and Immunity: a Leading Role of Stat3.  Nature Reviews Cancer. 9(11):798-809. PMID: 19851315. *Co-corresponding authors. Featured Article.

Kortylewski M, Swiderski P, Herrmann A, Kujawski, M, Wang L, Deng J, Kowolik C, Lee H, Soifer H, Forman S, Rossi J, Pardoll D, Jove R and Yu H. 2009. In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses. Nature Biotechnology, 27(10) 925-932.  PMID: 19749770. Featured/Cover article.

Wang L, Yi TS, Pardoll D, Zeng DF and Yu H. 2009. IL-17 can promote tumor growth through an IL-6/Stat3 signaling pathway. Journal of Experimental Medicine. 6206(7):1457-646.

Lee HY, Deng JH, Herrmann A, Niu GL, Xin H, Li Z-W, Kujawski M, Forman S, Jove R, Pardoll D and Yu H. 2009. Persistently-activated Stat3 maintains NF-kappaB constitutive activity in tumors. Cancer Cell.15(4):283-93. PMID: 19345327.
 
Kortylewski M, Kujawski M, Herrmann A, Wang L, and Yu H. 2009. Stat3 constrains the efficacies of TLR9 agonist-based immunotherapy. Cancer Research. 69(6):2497-2505. PMID: 19258507.
 
Xin H, Du Y, Herrmann A, Figlin R and Yu H. 2009. Stat3 inhibition by sunitinib induces apoptosis of renal cell carcinoma cells and reduces immunosuppressive cells. Cancer Research.69(6):2506-13. PMID: 19244102.
  
Kortylewski M, Xin H, Kujawski M, Lee H-Y, Liu Y, Harris T, Drake C, Pardoll D and Yu H.  2009. Regulation of the IL-23/IL-12 balance by Stat3 signaling in the tumor microenvironment. Cancer Cell.15: 114-123. PMID: 19185846.

Kujawski M, Kortylewski M, Lee H.Y, Herrmann A, Kay H, and Yu H.  2008. Stat3 mediates myeloid-cell-dependent tumor angiogenesis in mice. Journal of Clinical Investigation.118(10):3367-77. PMID: 18776941.
 
Kortylewski M and H Yu. 2008. Role of Stat3 in suppressing anti-tumor immunity.
Current Opinion in Immunology. 20(2):228-33. PMID: 18479894.
  
Yu* H, Kortylewski M and Pardoll D. 2007. Crosstalk between cancer and immune cells: the role of STAT3 in the tumor microenvironment. Nature Reviews Immunology.7:41-51. *Correspondent author.

Kortylewski M, Kujawski M, Wang T-H, Wei S, Zhang S, Pilon-Thomas S, Niu G-L, Kay H, Kerr WG, Mule J, Jove R, Pardoll D and Yu H. 2005. Inhibiting Stat-3 signaling in the hematopoietic system elicits multicomponent therapeutic antitumor immune responses. Nature Medicine.11(12):1314-21.

Yu* H and Jove* R. 2004. The Stats of Cancer – New Molecular Targets Come of Age. Nature Reviews Cancer, 4: 97-105. *Co-correspondent authors.

Wang T-H, Niu G-L, Kortylewski M, Burdelya L,  Shain K, Zhang S-M, Bhattacharya R,  Gabrilovich D, Heller R, Coppola D, Dalton D, Jove R, Pardoll D and Yu H. 2004. Regulation of the innate and adaptive immune responses by Stat3 signaling in tumor cells. Nature Medicine10:48-54.

This is a partial list. Full publications list available upon request. Information on this page may be self-reported. Last updated: 10/09

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