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 Selected Publications

Deng J, Liu Y, Lee H, Herrmann A, Zhang W, Zhang C, Shen S, Priceman S, Kujawski M,. Pal S, Raubitschek A, Hoon D., Forman S, Figlin R, Liu J, Jove R and Yu H. 2012. S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites. Cancer Cell. 21, 642–654

Lee HY, Zhang P, Herrmann H, Yang CY, Xin H, Wang CH, Hoon D, Forman S, Jove R, Riggs RD and Yu H. 2012. Acetylated STAT3 is crucial for methylation of tumor suppressor gene promoters and inhibition by resveratrol results in demethylation. PNAS. 2012 May 15;109(20):7765-9. PMID: 22547799

Lee H, Deng J, Kujawski M, Liu Y, Herrmann A, Kortylewski M, Horne D, Forman S, Jove R and Yu H. 2010. Stat3-induced expression of S1P1 receptor for the sphingolipid metabolite S1P is critical for persistent Stat3 activation in tumors. Nature Medicine. Dec;16(12):1421-8. PMID:  21102457

Yu H*, Pardoll D* and Jove* R.  STATs in Cancer Inflammation and Immunity: a Leading Role of Stat3. Nature Reviews Cancer. 9(11):798-809. PMID: 19851315. *co-corresponding authors.  Featured Article

Kortylewski M, Swiderski P, Herrmann A, Kujawski, M, Wang L, Deng J, Kowolik C, Lee H, Soifer H, Forman S, Rossi J, Pardoll D, Jove R and Yu H. 2009. In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses. Nature Biotechnology, 27(10) 925-932. PMID: 19749770. Featured/Cover article

Wang L, Yi TS, Pardoll D, Zeng DF and Yu H. 2009.  IL-17 can promote tumor growth through an IL-6/Stat3 signaling pathway. Journal of Experimental Medicine. 6206(7):1457-646

Lee HY, Deng JH, Herrmann A, Niu GL, Xin H, Li Z-W, Kujawski M, Forman S, Jove R, Pardoll D and Yu H. 2009. Persistently-activated Stat3 maintains NF-kappaB constitutive activity in tumors. Cancer Cell. 15(4):283-93. PMID: 19345327  

Kortylewski M, Xin H, Kujawski M, Lee H-Y, Liu Y, Harris T, Drake C, Pardoll D and Yu H.  2009. Regulation of the IL-23/IL-12 balance by Stat3 signaling in the tumor microenvironment.  Cancer Cell. 15: 114-123.  PMID: 19185846

Kujawski M, Kortylewski M, Lee H.Y, Herrmann A, Kay H, and Yu H. 2008.  Stat3 mediates myeloid-cell-dependent tumor angiogenesis in mice. Journal of Clinical Investigation. 118(10):3367-77. PMID: 18776941

Yu* H, Kortylewski M and Pardoll D.  2007. Crosstalk between cancer and immune cells: the role of STAT3 in the tumor microenvironment. Nature Reviews Immunology. 7:41-51. *Correspondent author

Kortylewski M, Kujawski M, Wang T-H, Wei S, Zhang S, Pilon-Thomas S, Niu G-L, Kay H, Kerr WG, Mule J, Jove R, Pardoll D and Yu H. 2005. Inhibiting Stat-3 signaling in the hematopoietic system elicits multicomponent therapeutic antitumor immune responses. Nature Medicine. 11(12):1314-21

Yu* H and Jove* R.  2004.  The Stats of Cancer – New Molecular Targets Come of Age. Nature Reviews Cancer, 4: 97-105. *Co-correspondent authors

Wang T-H, Niu G-L, Kortylewski M, Burdelya L, Shain K, Zhang S-M, Bhattacharya R,  Gabrilovich D, Heller R, Coppola D, Dalton D, Jove R, Pardoll D and Yu H. 2004. Regulation of the innate and adaptive immune responses by Stat3 signaling in tumor cells. Nature Medicine 10:48-54

This is a partial list. Full publications list available upon request. Information on this page may be self-reported. Last updated: 6/12

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