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 Selected Publications

Diamond DJ, Wang, Z, Zou W, Srivastava T, La Rosa C, Mandarino A, Forman SJ, Zaia JA, Britt WJ.  A Fusion Protein of HCMV IE1 exon4 and IE2 exon5 Stimulates Potent Cellular Immunity in an MVA Vaccine Vector.  Virology (in press), 2008.

Zhou J, Li H, Li S, Zaia J, Rossi JJ.  Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy.  Mol Ther (in press), 2008.

Zaia JA. The status of gene vectors for the treatment of diabetes. Cell Biochem Biophys 48(2-3): 183-90, 2007.

Lo HL, Chang T, Yam P, Marcovecchio PM, Li S, Zaia JA, Yee JK. Inhibition of HIV-1 replication with designed miRNAs expressed from RNA polymerase II promoters. Gene Ther 14(21): 1503-12, 2007.

Anderson J, Li MJ, Palmer B, Remling L, Li S, Yam P, Yee JK, Rossi J, Zaia J, Akkina R. Safety and efficacy of a lentiviral vector containing three anti-HIV genes--CCR5 ribozyme, tat-rev siRNA, and TAR decoy--in SCID-hu mouse-derived T cells. Mol Ther 15(6): 1182-8, 2007.

Lacey SF, LaRosa C, Zhou W, Sharma MC, Martinez J, Zaia JA. Functional Comparison of T-Cells Recognizing CMV pp65 and IE1 Polypeptides in HSCT and SOT Recipients, The Journal of Infectious Diseases 194 (10): 1410-1421 (2006).

Yam, P., Jensen, M., Akkina, R., Anderson, J., Villacres, MC, Wu, J., Zaia, JA, Yee, JK.  Ex Vivo Selection and Expansion of Cells Based on Expression of a Mutated Inosine Monophosphate Dehydrogenase 2 After HIV Vector-Transduction:  Effect on Lymphocytes, Monocytes, and CD34+ Stem Cells.  Mol Therapy 14:236-244 (2006).

Strayer, D. S., Akkina, R., Bunnell, B. A., Dropulic, B., Planelles, V., Pomerantz, R. J., Rossi, J. J., Zaia, J. A.  Current Status of Gene Therapy Strategies to Treat HIV/AIDS.  Mol Ther 11:823-842 (2005).

Li, M. J., Kim, J., Li, S., Zaia, J., Yee, J. K., Anderson, J., Akkina, R., Rossi, J. J. Long-term Inhibition of HIV-1 Infection in Primary Hematopoietic Cells by Lentiviral Vector Deliver of a Triple Combination of Anti-HIV shRNA, Anti-CCR5 Ribozyme, and a Nucleolar-Localizing TAR Decoy.  Mol Thera 12:900-909 (2005).

Krishnan A., Molina A., Zaia, J., Smith, D., Vasquez, D., Kogut, N., Falk, P. M., Rosenthal, J., Alvarnas, J., Forman, S. J.Durable Remissions with Autologous Stem Cell Transplantation for High-Risk HIV-Associated Lymphomas.  Blood 105:874-878 (2005).

Gallez-Hawkins G., Thao L., Lacey, S. F., Martinez, J., Li, X., Franck, A. E., Lomeli, N. A., Longmate, J., Diamond, D. J., Spielberger, R., Forman, S. J., Zaia, J. A., Cytomegalovirus Immune Reconstitution Occurs in Recipients of Allogeneic Hematopoietic Cell Transplants Irrespective of Detectable Cytomegalovirus Infection.  Biol Blood Marrow Transplant 11:890-902 (2005).

Lacey S.F., Martinez J., Gallez-Hawkins G., Thao L., Longmate J., Haq W., Spielberger R., Forman S.J., Zaia J.A. Simultaneous Reconstitution of Multiple Cytomegalovirus-Specific CD8+ Cell Populations with Divergent Functionality in Hematopoietic Stem-Cell Transplant Recipients.  The Journal of Infectious Diseases 191:977-984, 2005.

0. S. K. Lau, Y. Y. Chen, W. G. Chen, D. J. Diamond, A. N. Mamelak, J. A. Zaia, and L. M. Weiss. 2005. Lack of association of cytomegalovirus with human brain tumors. Mod.Pathol., 18: 838-843.

Gallez-Hawkins G., Li X, Franck, AE, Thao L, Lacey, S., Diamond D, Zaia JA. DNA and low titer, helper-free, recombinant AAV prime-boost vaccination for cytomegalovirus induces an immune response to CMV-pp65 and CMV-IE1 in transgenic HLA A*0201 mice. Vaccine, 23: 819-826, 2004.

Boeckh, M.; Nichols, W.G.; Papanicolaou, G.; Rubin, R.; Wingard, J.R.; Zaia, J.A. Cytomegalovirus in Hematopoietic Stem Cell Transplant Recipients: Current Status, Known Challenge, and future Strategies.  Biology of Blood and Marrow Transplantation, 9: 543-558, 2003. Michienzi, A., Castanotto, D., Lee, N.S., Li, S., Zaia, J.A. and Rossi, J.J.  RNA-Mediated Inhibition of HIV in a Gene Therapy Setting. Ther. Oligonucleotides, 1002: 63-71, 2003.

Lacey, S.; Villacres; M.C.; LaRosa, C.; Wang, Z.; Longmate, J.; Martinez, J.; Brewer, J.C.; Mekhoubad, S.; Maas, R.; Leedom, J. M.; Forman, S. J.; Zaia, J.A.; Diamond, D. J.: Relative dominance of HLA-B*07-restricted CD8+ T-lymphocyte immune responses to human cytomegalovirus pp65 in persons sharing HLA-A*02 and HLA-B*07 alleles. Hum Immunol, 64:440-52, 2003.

Li, M.-J., Bauer, G., Michienzi, A., Yee, J.-K., Lee, N.-S.,  Kim J., Li, S., Castanotto, D., Zaia, J.A., Rossi, J.J.   Inhibition of HIV-1 Infection by lentiviral vectors expressing  Pol III-promoted anti-HIV RNAs. Mol Ther. 8: 196-206, 2003.

Hawkins G, Villacres M, Li X, Sanborn M, Lomeli N, Zaia J: Use of Transgenic HLA A*0202/Kb and HHD II Mice To Evaluate Frequency of Cytomegalovirus IE1-Derived Peptide Usage in Eliciting Human CD8 Cytokine Response.  J Virol, 77:4457-4462, 2003.

Zaia JA. Prevention of cytomegalovirus disease in hematopoietic stem cell transplantation. Clin Infect Dis 2002;35:999-1004.

Zaia JA. Prevention and management of CMV-related problems after hematopoietic stem cell transplantation. Bone Marrow Transplant 2002;29:633-8.

Chang Z, Westaway S, Li S, Zaia JA, Rossi JJ, Scherer LJ. Enhanced expression and HIV-1 inhibition of chimeric tRNA(Lys3)-ribozymes under dual U6 snRNA and tRNA promoters. Mol Ther 2002;6:481-9.

Yam, P.Y.Y., Li, S., Wu, J., Hu, J., Zaia, J.A. & Yee, J.K. “Design of HIV vectors for efficient gene delivery into human hematopoietic cells” Mol. Ther. 5:479-484 2002.

Strayer D, Branco F, Zern MA, Yam P, Calarota SA, Nichols CN, Zaia JA, Rossi J, Li H, Parashar B, Ghosh S, Chowdhury JR. Durability of transgene expression and vector integration: recombinant SV40-derived gene therapy vectors. Mol Ther 2002;6:227-37.

Michienzi, A, Li S, Zaia JA, Rossi, JJ: A nucleolar TAR decoy inhibitor of HIV-1 replication.  Proc Natl Acad Sci U S A, 2002.

Krishnan A, Zaia J, Molina A: Stem cell transplantation and gene therapy for HIV-related lymphomas.  Journal of Hematotherapy & Stem Cell Research 11:765-775, 2002.

Zongli C, Westaway S, Li S, Zaia JA, Rossi JJ, Scherer LJ: Enhanced Expression and HIV-1 Inhibition of Chimeric rRNALys3-Rybozymes under Dual U6 snRNA and tRNA Promoters.  Molecular Therapy 6: 481-489, 2002.

Lacey F, Gallez-Hawkins G, Crooks M, Martinez J, Senitzer D, Forman SJ, Spielberger R, Zaia JA, Diamond DJ: Characterization of cytotoxic function of cmv-pp65-specific cd8* T-lymphocytes identified by HLA tetramers in recipients and donors of stem cell transplantation.  Transplantation, 2002 (in press).

Gallez-Hawkins, A, Lomeli, NA, Li X, Zhi-qiang Y, La Rosa C, Diamond DJ, Zaia JA. Kinase-deficient CMVpp65 triggers a CMVpp65 specific T-cell immune response in HLA-A*0201 transgenic mice after DNA immunization. Scan J of Immunology 55:592-598, 2002.

Levine A, D.T. S, Zaia JA, Krishnan A. Hematologic aspects of HIV/AIDS. In: Schechter GP, Broudy VC, Williams ME, eds. Hematology 2001: American Society of Hematology Education Program Book. Washington, D.C.: American Society of Hematology, 463-478, 2001.

Krishnan A, Molina A, Zaia JA, Nademanee A, Kogut N, Rosenthal J, Woo D, Foreman SJ.  Autologous stem cell transplantation for HIV-associated lymphoma.  Blood 98:3857-9, 2001.

Zaia JA, Gallez-Hawkins G, Li X, et al. Infrequent occurrence of natural mutations in the pp65(495-503) epitope sequence presented by the HLA A*0201 allele among human cytomegalovirus isolates. J Virol 2001;75:2472-4.

Yao Z-Q, Gallez-Hawkins G, Lomeli NA, Li X, Molinder K, Diamond DJ, and Zaia JA:  Site-directed mutation in a conserved kinase domain of human cytomegalovirus-pp65 with preservation of cytotoxic T lymphocyte targeting.  Vaccine 19:1628-35, 2001.


This is a partial list. Full publications list available upon request. Information on this page may be self-reported and subject to change at any time. Last reviewed 07/08. 

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