Defu Zeng, M.D.

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Associate Professor, Diabetes, Endocrinology & Metabolism
Associate Professor, Hematology & Hematopoietic Cell Transplantation
Full Member, Hematologic Malignancies Program, Comprehensive Cancer Center

Defu Zeng, M.D., associate professor, is an established scientist in the field of immune tolerance and joined the Department of Diabetes and Metabolic Diseases Research at City of Hope to apply his expertise in immunology to the fields of diabetes and islet transplantation. Dr. Zeng works closely with the islet transplantation and bone marrow transplantation teams at City of Hope to develop new strategies for inducing immune tolerance of transplanted islets via the establishment of mixed chimerism (coexistence of donor and recipient cells), using bone marrow stem cells and regulatory T-cells. Dr. Zeng also plans to expand his research to develop new immune therapy approaches to prevent type 1 diabetes.

Professional Experience

2008 - present, Associate Professor, Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute of City of Hope; Associate Professor, Department of Hematology & Hematopoietic Cell Transplantation, City of Hope, Duarte, CA

2003 - 2008, Assistant Professor, Departments of Diabetes/Endocrinology and Hematology/Bone Marrow Transplantation, Beckman Research Institute of City of Hope, Duarte, CA

2000 - 2003, Senior Research Scientist, Division of Immunology & Rheumatology, Department of Medicine, Stanford University School of Medicine, CA

1997 - 2000, Research Associate, Division of Immunology & Rheumatology, Department of Medicine, Stanford University School of Medicine, CA

1993 - 1997, Postdoctoral Research Fellow, Division of Immunology & Rheumatology, Department of Medicine, Stanford University School of Medicine, CA

1990 - 1993, Assistant Professor, Department of Pathophysiology, Fujian Medical College, Fuzhou, China.

1985 - 1990, Postgraduate Fellow, Department of Pathophysiology, Fujian Medical College, Fuzhou, China.

Education and Training

1993 - 1997, Stanford University, School of Medicine, CA., Postdoctoral Fellow, Immunology & Rheumatology

1990 - 1991, Chinese National Academy of Medical Sciences, Shanghai, China, Postgraduate Training, Cell Biology

1985 - 1990, Fujian Medical College, Fuzhou, China, Postgraduate Education, Pathophysiology

1980 - 1985, Fujian Medical College, Fuzhou, China, M.D., Medicine

This is an abbreviated document. Full CV available upon request. Information on this page may be self-reported and is subject to change at any time. Last updated: 06/09.

Honors and Awards

2008 - present, Ad Hoc member of NIH study section TTT

2007 - present, Members of NIH study section HAI

2004 - 2005, Innovative Grant, Juvenile Diabetes Research Foundation, USA

2002, Dorough Lupus Investigator Award, Arthritis Foundation, USA

2002, Travel Award, Federation of Clinical Immunology, USA

2001, Travel Award, Federation of Clinical Immunology, USA

2000, J. V. Satterfield Arthritis Investigator Award, Arthritis Foundation, USA

2000 - 2005, Investigator Award, Arthritis Foundation, USA

1998, New Investigator Award, Clinical Immunology Society, USA

1996, New Investigator Award, Clinical Immunology Society, USA

1995 - 1997, Postdoctoral Fellowship, Activated Cell Therapy Inc./Dendreon Corp., Mountain View, CA