A National Cancer Institute-designated Comprehensive Cancer Center

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Services

 
  • GXP ESI MSn analysis (nanoelectrospray) for peptide sequence confirmation.*
  • ESI Mass Spectrometry (nanoelectrospray) for determination of monoisotopic mass.
  • ESI MSn analysis (nanoelectrospray) for structure confirmation.
  • LC/MS analysis
  • LC/MS/MS analysis and quantitation of small molecules, metabolites, lipids, peptides, nucleosides.
  • Multidimensional peptide and protein separations by 2D LC and off-gel electrophoresis/LC.
  • In-gel Reduction, Alkylation, and Digestion of Coomassie Blue, Silver, and Fluorescent Dye stained gels
  • Proteomic analysis of paraffin embedded tissue sections
  • Solution Phase Reduction and Alkylation
  • Solution Phase Digestion
  • Sequest, Global Proteome Machine (GPM) and Protein Lynx Global Server Database Searches for Protein Identification
  • Label free quantitation of proteins in samples and expression analysis.

*Please note:  All GMP work requires Quality and Service Agreements PRIOR to analysis.  Please contact the facility manager for more information.
 

Services

Services

 
  • GXP ESI MSn analysis (nanoelectrospray) for peptide sequence confirmation.*
  • ESI Mass Spectrometry (nanoelectrospray) for determination of monoisotopic mass.
  • ESI MSn analysis (nanoelectrospray) for structure confirmation.
  • LC/MS analysis
  • LC/MS/MS analysis and quantitation of small molecules, metabolites, lipids, peptides, nucleosides.
  • Multidimensional peptide and protein separations by 2D LC and off-gel electrophoresis/LC.
  • In-gel Reduction, Alkylation, and Digestion of Coomassie Blue, Silver, and Fluorescent Dye stained gels
  • Proteomic analysis of paraffin embedded tissue sections
  • Solution Phase Reduction and Alkylation
  • Solution Phase Digestion
  • Sequest, Global Proteome Machine (GPM) and Protein Lynx Global Server Database Searches for Protein Identification
  • Label free quantitation of proteins in samples and expression analysis.

*Please note:  All GMP work requires Quality and Service Agreements PRIOR to analysis.  Please contact the facility manager for more information.
 
Research Shared Services

City of Hope embodies the spirit of scientific collaboration by sharing services and core facilities with colleagues here and around the world.
 

Recognized nationwide for its innovative biomedical research, City of Hope's Beckman Research Institute is home to some of the most tenacious and creative minds in science.
City of Hope is one of only 41 Comprehensive Cancer Centers in the country, the highest designation awarded by the National Cancer Institute to institutions that lead the way in cancer research, treatment, prevention and professional education.
Learn more about City of Hope's institutional distinctions, breakthrough innovations and collaborations.
Support Our Research
By giving to City of Hope, you support breakthrough discoveries in laboratory research that translate into lifesaving treatments for patients with cancer and other serious diseases.
 
 
 
 
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NEWS & UPDATES
  • Think twice before tossing out those hormone replacement pills. Although a new Lancet study suggests that hormone replacement therapy could increase a woman’s risk of ovarian cancer, a City of Hope expert urges women to keep this news in perspective. Hormone replacement therapy is prescribed to help allev...
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  • With precision medicine now a national priority, City of Hope has joined a novel research partnership designed to further understanding of cancer at the molecular level, ultimately leading to more targeted cancer treatments. The Oncology Research Information Exchange Network, or ORIEN, is the world’s larg...
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  • Each year, thousands of patients with hematologic malignancies undergo allogeneic stem cell transplantation (that is, they receive a donor’s stem cells), offering them a chance at cure. Graft-versus-host disease is a potentially deadly complication of this therapy and occurs in approximately 25 to 60 perc...
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  • Although many Hispanic women face a high risk of mutations in the BRCA1 and BRCA2 genes – increasing their risk of breast and ovarian cancer – screenings for these mutations can be prohibitively expensive in Mexico and other Latin American countries. As a result, too many women don’t get the information t...
  • Providing lung cancer treatments to patients when their cancer is at its earliest and most treatable stages will now be a more attainable goal: Medicare has agreed to cover lung cancer screening for those beneficiaries who meet the requirements. The only proven way to detect lung cancer early enough to save liv...
  • At City of Hope, innovative scientific research, important clinical studies and vital construction projects are all powered by philanthropy. Generous supporters fuel a powerful and diverse range of progress in science and medicine, enabling researchers and clinicians to improve cancer treatments and create cure...
  • Trevor Hoffman was only 21 when he was diagnosed with a rare form of cancer, but not even cancer could keep him off his motorcycles. (He has one for racing, and a couple just for fun.) Now a cancer survivor, Hoffman, who lives in La Verne, California, wrapped up his treatment Jan. 19 – just one day […]
  • Valentine’s Day is synonymous with dinner reservations, red roses, heart-shaped boxes of chocolates and — more often than not — unrealistically high expectations. Managing those expectations is great advice for all couples on Feb. 14 — and is especially important for couples confronting a cancer diagnosis. Focu...
  • With measles, what starts at a theme park in California definitely doesn’t stay at a theme park in California. Since the beginning of the current measles outbreak – traced to an initial exposure at Disneyland or Disney California Adventure during December – more than 100 people have been diagnosed with a diseas...
  • Even the most loving and secure relationship can be rattled by a life-threatening illness. When a woman is diagnosed with breast cancer, research shows one of the most important factors in helping her cope is having a supportive partner. But that partner can struggle with knowing what to say or how to best supp...
  • It’s been more than a century since Nobel Laureate Paul Ehrlich popularized the idea of a “magic bullet” targeting disease. Cancer researchers ever since have remained in hot pursuit of targeted therapies that home in on cancer cells while leaving normal cells unaffected. Linda Malkas, Ph.D., associate chair of...
  • Cancer patients face a daunting journey marked by challenges and uncertainties. For those undergoing bone marrow, or stem cell, transplantation, one complication poses a particular threat — chronic graft-versus-host disease (GVHD). Now, one researcher may have found a better way to control that threat. GVHD res...