A National Cancer Institute-designated Comprehensive Cancer Center

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Services

 
  • GXP ESI MSn analysis (nanoelectrospray) for peptide sequence confirmation.*
  • ESI Mass Spectrometry (nanoelectrospray) for determination of monoisotopic mass.
  • ESI MSn analysis (nanoelectrospray) for structure confirmation.
  • LC/MS analysis
  • LC/MS/MS analysis and quantitation of small molecules, metabolites, lipids, peptides, nucleosides.
  • Multidimensional peptide and protein separations by 2D LC and off-gel electrophoresis/LC.
  • In-gel Reduction, Alkylation, and Digestion of Coomassie Blue, Silver, and Fluorescent Dye stained gels
  • Proteomic analysis of paraffin embedded tissue sections
  • Solution Phase Reduction and Alkylation
  • Solution Phase Digestion
  • Sequest, Global Proteome Machine (GPM) and Protein Lynx Global Server Database Searches for Protein Identification
  • Label free quantitation of proteins in samples and expression analysis.

*Please note:  All GMP work requires Quality and Service Agreements PRIOR to analysis.  Please contact the facility manager for more information.
 

Services

Services

 
  • GXP ESI MSn analysis (nanoelectrospray) for peptide sequence confirmation.*
  • ESI Mass Spectrometry (nanoelectrospray) for determination of monoisotopic mass.
  • ESI MSn analysis (nanoelectrospray) for structure confirmation.
  • LC/MS analysis
  • LC/MS/MS analysis and quantitation of small molecules, metabolites, lipids, peptides, nucleosides.
  • Multidimensional peptide and protein separations by 2D LC and off-gel electrophoresis/LC.
  • In-gel Reduction, Alkylation, and Digestion of Coomassie Blue, Silver, and Fluorescent Dye stained gels
  • Proteomic analysis of paraffin embedded tissue sections
  • Solution Phase Reduction and Alkylation
  • Solution Phase Digestion
  • Sequest, Global Proteome Machine (GPM) and Protein Lynx Global Server Database Searches for Protein Identification
  • Label free quantitation of proteins in samples and expression analysis.

*Please note:  All GMP work requires Quality and Service Agreements PRIOR to analysis.  Please contact the facility manager for more information.
 
Research Shared Services

City of Hope embodies the spirit of scientific collaboration by sharing services and core facilities with colleagues here and around the world.
 

Recognized nationwide for its innovative biomedical research, City of Hope's Beckman Research Institute is home to some of the most tenacious and creative minds in science.
City of Hope is one of only 41 Comprehensive Cancer Centers in the country, the highest designation awarded by the National Cancer Institute to institutions that lead the way in cancer research, treatment, prevention and professional education.
Learn more about City of Hope's institutional distinctions, breakthrough innovations and collaborations.
Support Our Research
By giving to City of Hope, you support breakthrough discoveries in laboratory research that translate into lifesaving treatments for patients with cancer and other serious diseases.
 
 
 
 
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NEWS & UPDATES
  • In June 2012, 28-year-old Emily Bennett Taylor was getting ready to celebrate her second wedding anniversary with her college sweetheart when she discovered that she had Stage 4 lung cancer. Taylor was a former college athlete, had led a healthy and active lifestyle and had never smoked. She quickly began treat...
  • “Skin cancer” was pretty much the last thing on the mind of a healthy, outdoorsy kid like Tanner Harbin. “I like hockey – playing it and watching it,” the 23-year-old from San Dimas said. “I like to go off-roading with my dad – we have a Jeep and we have a cabin up in Big Bear, so […]
  • Skin cancer is an enticing field to be in these days. Just ask Laleh Melstrom, M.D. M.S., one of City of Hope’s newest surgeons. “In the last few years, melanoma has been the type of cancer that has really shown the most progress in terms of treatments,” Melstrom said. “It’s the one cancer in 2015 that is...
  • Skin cancer is the most common type of cancer in the United States today, and its incidence is on the rise. Forty to 50 percent of light-skinned Americans who live to age 65 will have skin cancer at least once in their lives. Most of these skin cancers – about 3.5 million cases – are the […]
  • The connection between lifestyle and cancer is real. Knowing that, what can individuals do to lower their risk? City of Hope physicians recently came together to answer that precise question, explaining the links between cancer and the choices we make that affect our health. Moderator Vijay Trisal M.D., medical...
  • White button mushrooms seem fairly innocuous as fungi go. Unlike portabellas, they don’t center stage at the dinner table, and unlike truffles, they’re not the subject of gourmand fervor. But appearances can be deceiving when it comes to these mild-mannered Clark Kents of the food world. In a study ...
  • Doctors often recommend preventive screenings for several cancers, based on hereditary or genetic factors, but brain tumors aren’t one of them. Primary brain tumors, which originate in the brain rather than spreading from another location, seem to develop at random, and doctors have little insight into wh...
  • Stopping cancer starts with research. To that end, STOP CANCER has awarded $525,000 in grants to City of Hope for 2015, supporting innovative research projects and recognizing the institution’s leadership in advancing cancer treatment and prevention. Founded in 1988, STOP CANCER underwrites the work of le...
  • Cancer may not be the disease many people think it is. Normally, cancer is considered to be a disease in which cells multiply at an extremely high, and unusual, rate – increasing the likelihood of genetic mutations. But increasingly, leading researchers at City of Hope and elsewhere are contending that cancer i...
  • “Of all forms of inequality, injustice in the health care system is the most shocking and inhumane.” By the time the Rev. Martin Luther King Jr. spoke those words in Chicago in 1966, the Civil Rights Act had been passed, the Voting Rights Act was the law of the land and the March on Washington was […]
  • Eight years ago, Matthew Loscalzo surprised himself by accepting the offer to become City of Hope’s administrative director of the Sheri & Les Biller Patient and Family Resource Center and executive director of the Department of Supportive Care Medicine. At the time, he was administrative director of the Sc...
  • The mental fog that patients can experience after undergoing chemotherapy treatment for cancer has a name: “chemo brain.” “Many patients report hearing or reading about chemotherapy-related cognitive deficits, but few are actually prepared to deal with these changes,” said Celina Lemon, M.A., an occupational th...
  • Cancer treatments have improved over the years, but one potential source of treatments and cures remains largely untapped: nature. Blueberries, cinnamon, xinfeng, grape seed (and skin) extract, mushrooms, barberry and pomegranates all contain compounds with the potential to treat or prevent cancer. Scientists a...
  • In the U.S., there are more new cases of skin cancer than the combined incidence of cancers of the breast, prostate and lung, according to the American Cancer Society. Each year, 5 million people are treated for skin cancer. Here, Hans Schoellhammer, M.D., assistant clinical professor at City of Hope | Ant...
  • As public health experts know, health improvement starts in the community. Now, City of Hope  has been recognized for its efforts to improve the lives of residents of its own community. The institution will receive funding from the Institute for Healthcare Improvement  to support promising community-based work ...