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MoLAR Meeting
The Meeting of LA area Receptor labs (MoLAR) is an informal meeting that provides a friendly forum for exchange of ideas and new and often unpublished research. MoLAR brings together labs in the Southern California region that study related fields of gene regulation and nuclear receptor function and mechanism. The topics span a wide array of biological contexts, including metabolism, diabetes and diabetic complications, cancer, cardiovascular biology and comparative physiology. The meeting aims to provide a small and collegial environment to discuss your projects, interact and network with leading scientists and their lab groups who are involved in related fields of research. It is a great opportunity for postdoctoral fellows and doctoral trainees to receive insightful feedback on their research from experts and to discover new areas for collaboration.  We encourage participation from all labs in attendance and the presentation of both projects in early stages (15 minute “poster” talks) or more developed stories in longer format talks (25 minutes). As always, the success of the conference comes from lively participation and interaction.
The following laboratories participate regularly in the MoLAR meeting:
(Click on name to view PubMed references)
Lab Institution
Ruben Abagyan The Scripps Research Institute
David Ann City of Hope
Bruce Blumberg University of California at Irvine
Shiuan Chen City of Hope
Gerhard Coetzee University of Southern California
Andrea Hevener-Bell University of California at Los Angeles
Wendong Huang City of Hope
Janice Huss City of Hope
Chris Jamieson University of California at Los Angeles
Jeremey Jones City of Hope
Natasha Kralli The Scripps Research Institute
Katia Lamia The Scripps Research Institute
Rama Natarajan City of Hope
Enrique Saez The Scripps Research Institute
Yanhong Shi City of Hope
Frances M. Sladek University of California at Riverside
Michael Stallcup University of Southern California
Charles Stephensen University of California at Davis
Henry Sucov University of Southern California
Peter Tontonoz University of California at Los Angeles

Next Meeting

Next Meeting:  April 25, 2014
Registration Deadline: April 18, 2014
Guest Speaker: Bruce Blumberg, Ph.D. (University of California at Irvine, Irvine, CA)
Dr. Blumberg initially described the steroid and xenobiotic receptor, SXR or PXR (NR1I2). His lab has been at the forefront of understanding biology and mechanisms of environmental toxicants with particular emphasis on endocrine disruptors. Recently the Blumberg lab’s work on understanding the effects of gestational diet and exposure to toxicants (e.g., tributyltin) on development and obesity in offspring has received widespread media coverage and increased public awareness of environmental obesogens and the heritability of obesity risk.
Title of Presentation: Impacts in of gestational diet and toxicant exposure on obesity risk in offspring
Welcome/Breakfast (10:00 am)
Platt #3 Conference Room
Impacts in of gestational diet and toxicant exposure on obesity risk in offspring (10:10 am)
Bruce Blumberg, Ph.D. (University of California at Irvine, Irvine, CA)
HNF4a modulates systemic response to DIO (11:05 am)
Sladek Lab (University of California at Riverside, Riverside, CA)
Break (11:35 am)
Role of ERRalpha in skeletal muscle metabolic adaptation to endurance exercise (11:55 am)
Sam LaBarge (City of Hope, Duarte, CA)
The Hic-5 transcriptional coregulator gene-selective regulation of GR occupancy (12:15 pm)
Rajas Chodankar, Ph.D. (University of Southern California, Los Angeles, CA)
Lunch (12:45 pm)
γ-Carboxylation of the Androgen receptor and clinical relationship to prostate cancer (2:15 pm)
Ben Yi Tew (City of Hope, Duarte, CA)
Talk TBA (2:40 pm)
AroER Tri-Screen, a high throughput screening system for endocrine disruptors targeting ER and aromatase (3:00 pm)
Noriko Kanaya (City of Hope, Duarte, CA)
Break (3:30 pm)
Bile acid, CAMKII and Liver carcinogenesis (3:50 pm)
Xiaoxiao Ma (City of Hope, Duarte, CA)
Talk TBA (4:15 pm)
Amy Leung, Ph.D. (City of Hope, Duarte, CA)
Nuclear Receptor DNA Binding Project (4:40 pm)
Sladek Lab (University of California at Riverside, Riverside, CA)
SGK3, an estrogen and androgen regulated kinase involved in endocrine therapy resistance (5:00 pm)
Yuan-Zhong Wang, Ph.D. (City of Hope, Duarte, CA)
Talk TBA (5:20 pm)
Yoshitake Cho, Ph.D. (The Scripps Research Institute, La Jolla, CA)
Discussion Hour (5:40 pm)
Future Meetings: April 24, 2015

Meeting Location & Directions

City of Hope
Platt #3 Conference Room
1500 E. Duarte Road, Duarte, CA 91010
City of Hope is located in Duarte just off the 210 freeway, one exit west of the junction of the 210 and 605 freeways. Exit the 210 freeway at Buena Vista and proceed south toward Duarte Road. Turn left onto Duarte Road and proceed east for 0.4 miles, passing an entrance labeled Beckman Research Institute. Use the main entrance which has a guard booth. Ask at the guard booth for parking instructions. The meeting is held in Platt #3 Conference Room. 
Click here for a campus map and personalized directions to City of Hope.

Registration & AV Info

Registration Fees
$60 - Physician/Scientist/Industry Professional
The next MoLAR meeting is scheduled for Friday, April 25, 2014.  To participate, please register by April 18, 2014.  

Please, no late payments or payments at the door.  We need an accurate head count for facilities and meals. Thank you.
How to Register
Fax: Print the registration form , complete and fax to: 626-301-8136.
Mail:  Print the registration form , complete and mail to: Sarah Tomeck, City of Hope, Division of Molecular Diabetes Research, 1500 East Duarte Road, Room 2001, Duarte, CA, 91010  (Checks/money orders must be payable to City of Hope-MoLAR Meeting.)
Cancellation and Refund Policy
Unlike most meetings, the MoLAR registration deadline is extremely close to the meeting date. As a result, charges are immediately incurred upon registration and refunds will not be granted.
Audio Visual Information
MAC and PC-operated computers and a digital projector will be available. Please bring your Powerpoint presentations on a CD or USB flash drive. There is no need to bring your own computer. In fact, we want to avoid the complications associated with linking individual computers to the projector. All other equipment should be requested well in advance.
Sarah Tomeck
Phone: 626-256-4673, ext. 62833
Fax: 626-301-8136


Presentations at the MoLAR meeting include new and unpublished results. In order to preserve this spirit, all unpublished information that is presented or discussed is considered confidential. By attending the meeting, all participants agree not to discuss or disclose any unpublished information with those who are not present at the meeting or those who are not immediate members of their lab. Such information will remain confidential until the information (1) has been published or presented publicly or (2) the speaker has given permission to discuss the information.
Research Videos
Our Scientists

Our research laboratories are led by the best and brightest minds in scientific research.

Research Shared Services

City of Hope embodies the spirit of scientific collaboration by sharing services and core facilities with colleagues here and around the world.

Technology & Licensing
The Center for Applied Technology Development offers broad expertise in
technology transfer and licensing, biologics manufacturing, quality assurance and regulatory affairs.

City of Hope offers a number of exciting fellowships and residencies in laboratory research, administration, clinical applications and other areas.
  • Eleven years ago, lymphoma patient Christine Pechera began the long road toward a cancer-free life. She had been diagnosed with non-Hodgkin lymphoma and told by doctors elsewhere that her lifespan likely would be measured in months, not years. Refusing to give up, she came to City of Hope for a second opinion. ...
  • Brain surgery is not for the faint of heart. It takes courage, as well as curiosity and compassion. The truly great surgeons also have a desire to find new, and better ways, of healing the brain. Enter Behnam Badie, M.D., chief of neurosurgery at City of Hope. Now a pioneer in brain tumor treatment, Badie enter...
  • Elizabeth Budde, M.D., Ph.D., wants to encourage infighting. She aims to turn the immune system on itself — to the benefit of patients with acute myeloid leukemia, or AML. AML arises when abnormal white blood cells grow out of control, amassing in the bone marrow and interfering with normal blood cell developme...
  • Six, to date; more soon. Outpatient bone marrow transplants, that is. Finding new ways to deliver quality care with the greatest benefit is a priority for a patient-centered institution like City of Hope. For example, not every bone marrow transplant patient needs to check into the hospital for treatment. In fa...
  • The best measure of success in the fight against cancer is in lives saved and families intact, in extra days made special simply because they exist. Yuman Fong, M.D., chair of the Department of Surgery at City of Hope, understands what precedes that special awareness. When cancer strikes, one minute a person ma...
  • In cancer, expertise matters. So do survival rates, patient safety, patient services and many other factors. City of Hope understands this, as does U.S.News & World Report. The magazine’s 2014-2015 list of best hospitals for cancer once again includes City of Hope, ranking the institution 12 out of 900 elig...
  • At 29, Kommah McDowell was a successful young professional engaged to be married to her best friend. She worked in the financial services sector and kick-boxed to keep in shape and to relax. Then came the diagnosis of triple-negative inflammatory breast cancer, a rare and very aggressive form of breast cancer. ...
  • The well-known drug tamoxifen might not always be the best choice for premenopausal women who have undergone treatment for breast cancer and face a heightened risk of recurrence. A new study suggests that the aromatase inhibitor exemestane, or Aromasin, works slightly better than tamoxifen in preventing cancer ...
  • At age 44, Bridget Hanchette, a mother of three from La Crosse, Wisconsin, was diagnosed with grade IV glioblastoma, the most aggressive type of malignant brain tumor. The cancer grows and spreads quickly, making it difficult to treat. Most patients with this diagnosis are not given much hope, but Hanchette’s i...
  • Survival rates for childhood cancer have improved tremendously over the past few decades, but postcancer care hasn’t always kept up. More children than ever are now coping with long-term complications and side effects caused by their disease and treatment — one of those being learning difficulties. A new ...
  • When Sheldon Querido, a retired manufacturer’s representative, was diagnosed with bladder cancer, his doctor told him that he’d need to have his bladder removed – and that he’d have to wear an external urine-collection bag for the rest of his life. “My first response was ‘I donR...
  • To stop smoking, two approaches might be better than one. A new study has found that using the medication varenicline, or Chantix – along with nicotine patches – was more effective than the medicine alone in helping people quit. The study, conducted by Stellanbosch University in Cape Town, South Africa, and pub...
  • John Cloer was three months shy of his third birthday in 2004 when he was diagnosed with acute lymphoblastic leukemia. For the next three and a half years, he received chemotherapy at City of Hope, finally obtaining long-term remission. His parents Bill and Gina, along with John and his younger brother Steve, r...
  • News about the risks or benefits of widespread cancer screening seem to arrive daily – 3D mammography for breast cancer, CT scans for lung cancer, PSA tests for prostate cancer and now pelvic exams for some women’s cancers. Missing in the headlines is a reflection of how cancer detection is evolving. Today’s ca...
  • Adults with sickle cell disease soon may have a new treatment option: bone marrow transplants. Children with sickle cell disease have been treated successfully with transplantation of bone marrow, more officially known as hematopoietic stem cells, from other people. But the procedure has been less successful in...