The Meeting of LA area Receptor labs (MoLAR) is an informal meeting that provides a friendly forum for exchange of ideas and new and often unpublished research. MoLAR brings together labs in the Southern California region that study related fields of gene regulation and nuclear receptor function and mechanism. The topics span a wide array of biological contexts, including metabolism, diabetes and diabetic complications, cancer, cardiovascular biology and comparative physiology. The meeting aims to provide a small and collegial environment to discuss your projects, interact and network with leading scientists and their lab groups who are involved in related fields of research. It is a great opportunity for postdoctoral fellows and doctoral trainees to receive insightful feedback on their research from experts and to discover new areas for collaboration. We encourage participation from all labs in attendance and the presentation of both projects in early stages (15 minute “poster” talks) or more developed stories in longer format talks (25 minutes). As always, the success of the conference comes from lively participation and interaction.
The following laboratories participate regularly in the MoLAR meeting:
(Click on name to view PubMed references)
Guest Speaker: Bruce Blumberg, Ph.D. (University of California at Irvine, Irvine, CA)
Dr. Blumberg initially described the steroid and xenobiotic receptor, SXR or PXR (NR1I2). His lab has been at the forefront of understanding biology and mechanisms of environmental toxicants with particular emphasis on endocrine disruptors. Recently the Blumberg lab’s work on understanding the effects of gestational diet and exposure to toxicants (e.g., tributyltin) on development and obesity in offspring has received widespread media coverage and increased public awareness of environmental obesogens and the heritability of obesity risk. Title of Presentation: Impacts in of gestational diet and toxicant exposure on obesity risk in offspring
Welcome/Breakfast (10:00 am)
Platt #3 Conference Room
Impacts in of gestational diet and toxicant exposure on obesity risk in offspring (10:10 am)
Bruce Blumberg, Ph.D. (University of California at Irvine, Irvine, CA)
HNF4a modulates systemic response to DIO (11:05 am)
Sladek Lab (University of California at Riverside, Riverside, CA)
Break (11:35 am)
Role of ERRalpha in skeletal muscle metabolic adaptation to endurance exercise (11:55 am)
Sam LaBarge (City of Hope, Duarte, CA)
The Hic-5 transcriptional coregulator gene-selective regulation of GR occupancy (12:15 pm)
Rajas Chodankar, Ph.D. (University of Southern California, Los Angeles, CA)
Lunch (12:45 pm)
γ-Carboxylation of the Androgen receptor and clinical relationship to prostate cancer (2:15 pm)
Ben Yi Tew (City of Hope, Duarte, CA)
Talk TBA (2:40 pm)
AroER Tri-Screen, a high throughput screening system for endocrine disruptors targeting ER and aromatase (3:00 pm)
Noriko Kanaya (City of Hope, Duarte, CA)
Break (3:30 pm)
Bile acid, CAMKII and Liver carcinogenesis (3:50 pm)
Xiaoxiao Ma (City of Hope, Duarte, CA)
Talk TBA (4:15 pm)
Amy Leung, Ph.D. (City of Hope, Duarte, CA)
Nuclear Receptor DNA Binding Project (4:40 pm)
Sladek Lab (University of California at Riverside, Riverside, CA)
SGK3, an estrogen and androgen regulated kinase involved in endocrine therapy resistance (5:00 pm)
Yuan-Zhong Wang, Ph.D. (City of Hope, Duarte, CA)
Talk TBA (5:20 pm)
Yoshitake Cho, Ph.D. (The Scripps Research Institute, La Jolla, CA)
City of Hope
Platt #3 Conference Room
1500 E. Duarte Road, Duarte, CA 91010
City of Hope is located in Duarte just off the 210 freeway, one exit west of the junction of the 210 and 605 freeways. Exit the 210 freeway at Buena Vista and proceed south toward Duarte Road. Turn left onto Duarte Road and proceed east for 0.4 miles, passing an entrance labeled Beckman Research Institute. Use the main entrance which has a guard booth. Ask at the guard booth for parking instructions. The meeting is held in Platt #3 Conference Room.
Click here for a campus map and personalized directions to City of Hope.
Mail:Print the registration form
, complete and mail to: Sarah Tomeck, City of Hope, Division of Molecular Diabetes Research, 1500 East Duarte Road, Room 2001, Duarte, CA, 91010 (Checks/money orders must be payable to City of Hope-MoLAR Meeting.)
Cancellation and Refund Policy
Unlike most meetings, the MoLAR registration deadline is extremely close to the meeting date. As a result, charges are immediately incurred upon registration and refunds will not be granted.
Audio Visual Information
MAC and PC-operated computers and a digital projector will be available. Please bring your Powerpoint presentations on a CD or USB flash drive. There is no need to bring your own computer. In fact, we want to avoid the complications associated with linking individual computers to the projector. All other equipment should be requested well in advance.
Presentations at the MoLAR meeting include new and unpublished results. In order to preserve this spirit, all unpublished information that is presented or discussed is considered confidential. By attending the meeting, all participants agree not to discuss or disclose any unpublished information with those who are not present at the meeting or those who are not immediate members of their lab. Such information will remain confidential until the information (1) has been published or presented publicly or (2) the speaker has given permission to discuss the information.
Eleven years ago, lymphoma patient Christine Pechera began the long road toward a cancer-free life. She had been diagnosed with non-Hodgkin lymphoma and told by doctors elsewhere that her lifespan likely would be measured in months, not years. Refusing to give up, she came to City of Hope for a second opinion. ...
Brain surgery is not for the faint of heart. It takes courage, as well as curiosity and compassion. The truly great surgeons also have a desire to find new, and better ways, of healing the brain. Enter Behnam Badie, M.D., chief of neurosurgery at City of Hope. Now a pioneer in brain tumor treatment, Badie enter...
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To stop smoking, two approaches might be better than one. A new study has found that using the medication varenicline, or Chantix – along with nicotine patches – was more effective than the medicine alone in helping people quit. The study, conducted by Stellanbosch University in Cape Town, South Africa, and pub...
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