A National Cancer Institute-designated Comprehensive Cancer Center

Make an appointment: 800-826-HOPE
MoLAR Bookmark and Share

MoLAR Meeting

Overview
The Meeting of LA area Receptor labs (MoLAR) is an informal meeting that provides a friendly forum for exchange of ideas and new and often unpublished research. MoLAR brings together labs in the Southern California region that study related fields of gene regulation and nuclear receptor function and mechanism. The topics span a wide array of biological contexts, including metabolism, diabetes and diabetic complications, cancer, cardiovascular biology and comparative physiology. The meeting aims to provide a small and collegial environment to discuss your projects, interact and network with leading scientists and their lab groups who are involved in related fields of research. It is a great opportunity for postdoctoral fellows and doctoral trainees to receive insightful feedback on their research from experts and to discover new areas for collaboration.  We encourage participation from all labs in attendance and the presentation of both projects in early stages (15 minute “poster” talks) or more developed stories in longer format talks (25 minutes). As always, the success of the conference comes from lively participation and interaction.
 
The following laboratories participate regularly in the MoLAR meeting:
(Click on name to view PubMed references)
 
Lab Institution
Ruben Abagyan The Scripps Research Institute
David Ann City of Hope
Bruce Blumberg University of California at Irvine
Shiuan Chen City of Hope
Gerhard Coetzee University of Southern California
Andrea Hevener-Bell University of California at Los Angeles
Wendong Huang City of Hope
Janice Huss City of Hope
Chris Jamieson University of California at Los Angeles
Jeremey Jones City of Hope
Natasha Kralli The Scripps Research Institute
Katia Lamia The Scripps Research Institute
Rama Natarajan City of Hope
Enrique Saez The Scripps Research Institute
Yanhong Shi City of Hope
Frances M. Sladek University of California at Riverside
Michael Stallcup University of Southern California
Charles Stephensen University of California at Davis
Henry Sucov University of Southern California
Peter Tontonoz University of California at Los Angeles
 

Next Meeting

Next Meeting:  April 25, 2014
Registration Deadline: April 18, 2014
 
Guest Speaker: Bruce Blumberg, Ph.D. (University of California at Irvine, Irvine, CA)
Dr. Blumberg initially described the steroid and xenobiotic receptor, SXR or PXR (NR1I2). His lab has been at the forefront of understanding biology and mechanisms of environmental toxicants with particular emphasis on endocrine disruptors. Recently the Blumberg lab’s work on understanding the effects of gestational diet and exposure to toxicants (e.g., tributyltin) on development and obesity in offspring has received widespread media coverage and increased public awareness of environmental obesogens and the heritability of obesity risk.
Title of Presentation: Impacts in of gestational diet and toxicant exposure on obesity risk in offspring
 
Program
Welcome/Breakfast (10:00 am)
Platt #3 Conference Room
 
Impacts in of gestational diet and toxicant exposure on obesity risk in offspring (10:10 am)
Bruce Blumberg, Ph.D. (University of California at Irvine, Irvine, CA)
 
HNF4a modulates systemic response to DIO (11:05 am)
Sladek Lab (University of California at Riverside, Riverside, CA)
 
Break (11:35 am)
 
Role of ERRalpha in skeletal muscle metabolic adaptation to endurance exercise (11:55 am)
Sam LaBarge (City of Hope, Duarte, CA)
 
The Hic-5 transcriptional coregulator gene-selective regulation of GR occupancy (12:15 pm)
Rajas Chodankar, Ph.D. (University of Southern California, Los Angeles, CA)
 
Lunch (12:45 pm)
 
γ-Carboxylation of the Androgen receptor and clinical relationship to prostate cancer (2:15 pm)
Ben Yi Tew (City of Hope, Duarte, CA)
 
Talk TBA (2:40 pm)
 
AroER Tri-Screen, a high throughput screening system for endocrine disruptors targeting ER and aromatase (3:00 pm)
Noriko Kanaya (City of Hope, Duarte, CA)
 
Break (3:30 pm)
 
Bile acid, CAMKII and Liver carcinogenesis (3:50 pm)
Xiaoxiao Ma (City of Hope, Duarte, CA)
 
Talk TBA (4:15 pm)
Amy Leung, Ph.D. (City of Hope, Duarte, CA)
 
Nuclear Receptor DNA Binding Project (4:40 pm)
Sladek Lab (University of California at Riverside, Riverside, CA)
 
SGK3, an estrogen and androgen regulated kinase involved in endocrine therapy resistance (5:00 pm)
Yuan-Zhong Wang, Ph.D. (City of Hope, Duarte, CA)
 
Talk TBA (5:20 pm)
Yoshitake Cho, Ph.D. (The Scripps Research Institute, La Jolla, CA)
 
Discussion Hour (5:40 pm)
 
 
Future Meetings: April 24, 2015

Meeting Location and Directions

Location:
City of Hope
Platt #3 Conference Room
1500 E. Duarte Road, Duarte, CA 91010
 
Directions:
City of Hope is located in Duarte just off the 210 freeway, one exit west of the junction of the 210 and 605 freeways. Exit the 210 freeway at Buena Vista and proceed south toward Duarte Road. Turn left onto Duarte Road and proceed east for 0.4 miles, passing an entrance labeled Beckman Research Institute. Use the main entrance which has a guard booth. Ask at the guard booth for parking instructions. The meeting is held in Platt #3 Conference Room. 
 
Click here for a campus map and personalized directions to City of Hope.
 

Registration and AV Info

Registration Fees
$60 - Physician/Scientist/Industry Professional
 
The next MoLAR meeting is scheduled for Friday, April 25, 2014.  To participate, please register by April 18, 2014.  

Please, no late payments or payments at the door.  We need an accurate head count for facilities and meals. Thank you.
 
How to Register
Fax: Print the registration form , complete and fax to: 626-301-8136.
 
Mail:  Print the registration form , complete and mail to: Sarah Tomeck, City of Hope, Division of Molecular Diabetes Research, 1500 East Duarte Road, Room 2001, Duarte, CA, 91010  (Checks/money orders must be payable to City of Hope-MoLAR Meeting.)
 
Cancellation and Refund Policy
Unlike most meetings, the MoLAR registration deadline is extremely close to the meeting date. As a result, charges are immediately incurred upon registration and refunds will not be granted.
 
Audio Visual Information
MAC and PC-operated computers and a digital projector will be available. Please bring your Powerpoint presentations on a CD or USB flash drive. There is no need to bring your own computer. In fact, we want to avoid the complications associated with linking individual computers to the projector. All other equipment should be requested well in advance.
 
Questions?
Sarah Tomeck
Phone: 626-256-4673, ext. 62833
Fax: 626-301-8136
 
 
 
 
 

Confidentiality

Presentations at the MoLAR meeting include new and unpublished results. In order to preserve this spirit, all unpublished information that is presented or discussed is considered confidential. By attending the meeting, all participants agree not to discuss or disclose any unpublished information with those who are not present at the meeting or those who are not immediate members of their lab. Such information will remain confidential until the information (1) has been published or presented publicly or (2) the speaker has given permission to discuss the information.

MoLAR

MoLAR Meeting

Overview
The Meeting of LA area Receptor labs (MoLAR) is an informal meeting that provides a friendly forum for exchange of ideas and new and often unpublished research. MoLAR brings together labs in the Southern California region that study related fields of gene regulation and nuclear receptor function and mechanism. The topics span a wide array of biological contexts, including metabolism, diabetes and diabetic complications, cancer, cardiovascular biology and comparative physiology. The meeting aims to provide a small and collegial environment to discuss your projects, interact and network with leading scientists and their lab groups who are involved in related fields of research. It is a great opportunity for postdoctoral fellows and doctoral trainees to receive insightful feedback on their research from experts and to discover new areas for collaboration.  We encourage participation from all labs in attendance and the presentation of both projects in early stages (15 minute “poster” talks) or more developed stories in longer format talks (25 minutes). As always, the success of the conference comes from lively participation and interaction.
 
The following laboratories participate regularly in the MoLAR meeting:
(Click on name to view PubMed references)
 
Lab Institution
Ruben Abagyan The Scripps Research Institute
David Ann City of Hope
Bruce Blumberg University of California at Irvine
Shiuan Chen City of Hope
Gerhard Coetzee University of Southern California
Andrea Hevener-Bell University of California at Los Angeles
Wendong Huang City of Hope
Janice Huss City of Hope
Chris Jamieson University of California at Los Angeles
Jeremey Jones City of Hope
Natasha Kralli The Scripps Research Institute
Katia Lamia The Scripps Research Institute
Rama Natarajan City of Hope
Enrique Saez The Scripps Research Institute
Yanhong Shi City of Hope
Frances M. Sladek University of California at Riverside
Michael Stallcup University of Southern California
Charles Stephensen University of California at Davis
Henry Sucov University of Southern California
Peter Tontonoz University of California at Los Angeles
 

Next Meeting

Next Meeting

Next Meeting:  April 25, 2014
Registration Deadline: April 18, 2014
 
Guest Speaker: Bruce Blumberg, Ph.D. (University of California at Irvine, Irvine, CA)
Dr. Blumberg initially described the steroid and xenobiotic receptor, SXR or PXR (NR1I2). His lab has been at the forefront of understanding biology and mechanisms of environmental toxicants with particular emphasis on endocrine disruptors. Recently the Blumberg lab’s work on understanding the effects of gestational diet and exposure to toxicants (e.g., tributyltin) on development and obesity in offspring has received widespread media coverage and increased public awareness of environmental obesogens and the heritability of obesity risk.
Title of Presentation: Impacts in of gestational diet and toxicant exposure on obesity risk in offspring
 
Program
Welcome/Breakfast (10:00 am)
Platt #3 Conference Room
 
Impacts in of gestational diet and toxicant exposure on obesity risk in offspring (10:10 am)
Bruce Blumberg, Ph.D. (University of California at Irvine, Irvine, CA)
 
HNF4a modulates systemic response to DIO (11:05 am)
Sladek Lab (University of California at Riverside, Riverside, CA)
 
Break (11:35 am)
 
Role of ERRalpha in skeletal muscle metabolic adaptation to endurance exercise (11:55 am)
Sam LaBarge (City of Hope, Duarte, CA)
 
The Hic-5 transcriptional coregulator gene-selective regulation of GR occupancy (12:15 pm)
Rajas Chodankar, Ph.D. (University of Southern California, Los Angeles, CA)
 
Lunch (12:45 pm)
 
γ-Carboxylation of the Androgen receptor and clinical relationship to prostate cancer (2:15 pm)
Ben Yi Tew (City of Hope, Duarte, CA)
 
Talk TBA (2:40 pm)
 
AroER Tri-Screen, a high throughput screening system for endocrine disruptors targeting ER and aromatase (3:00 pm)
Noriko Kanaya (City of Hope, Duarte, CA)
 
Break (3:30 pm)
 
Bile acid, CAMKII and Liver carcinogenesis (3:50 pm)
Xiaoxiao Ma (City of Hope, Duarte, CA)
 
Talk TBA (4:15 pm)
Amy Leung, Ph.D. (City of Hope, Duarte, CA)
 
Nuclear Receptor DNA Binding Project (4:40 pm)
Sladek Lab (University of California at Riverside, Riverside, CA)
 
SGK3, an estrogen and androgen regulated kinase involved in endocrine therapy resistance (5:00 pm)
Yuan-Zhong Wang, Ph.D. (City of Hope, Duarte, CA)
 
Talk TBA (5:20 pm)
Yoshitake Cho, Ph.D. (The Scripps Research Institute, La Jolla, CA)
 
Discussion Hour (5:40 pm)
 
 
Future Meetings: April 24, 2015

Meeting Location & Directions

Meeting Location and Directions

Location:
City of Hope
Platt #3 Conference Room
1500 E. Duarte Road, Duarte, CA 91010
 
Directions:
City of Hope is located in Duarte just off the 210 freeway, one exit west of the junction of the 210 and 605 freeways. Exit the 210 freeway at Buena Vista and proceed south toward Duarte Road. Turn left onto Duarte Road and proceed east for 0.4 miles, passing an entrance labeled Beckman Research Institute. Use the main entrance which has a guard booth. Ask at the guard booth for parking instructions. The meeting is held in Platt #3 Conference Room. 
 
Click here for a campus map and personalized directions to City of Hope.
 

Registration & AV Info

Registration and AV Info

Registration Fees
$60 - Physician/Scientist/Industry Professional
 
The next MoLAR meeting is scheduled for Friday, April 25, 2014.  To participate, please register by April 18, 2014.  

Please, no late payments or payments at the door.  We need an accurate head count for facilities and meals. Thank you.
 
How to Register
Fax: Print the registration form , complete and fax to: 626-301-8136.
 
Mail:  Print the registration form , complete and mail to: Sarah Tomeck, City of Hope, Division of Molecular Diabetes Research, 1500 East Duarte Road, Room 2001, Duarte, CA, 91010  (Checks/money orders must be payable to City of Hope-MoLAR Meeting.)
 
Cancellation and Refund Policy
Unlike most meetings, the MoLAR registration deadline is extremely close to the meeting date. As a result, charges are immediately incurred upon registration and refunds will not be granted.
 
Audio Visual Information
MAC and PC-operated computers and a digital projector will be available. Please bring your Powerpoint presentations on a CD or USB flash drive. There is no need to bring your own computer. In fact, we want to avoid the complications associated with linking individual computers to the projector. All other equipment should be requested well in advance.
 
Questions?
Sarah Tomeck
Phone: 626-256-4673, ext. 62833
Fax: 626-301-8136
 
 
 
 
 

Confidentiality

Confidentiality

Presentations at the MoLAR meeting include new and unpublished results. In order to preserve this spirit, all unpublished information that is presented or discussed is considered confidential. By attending the meeting, all participants agree not to discuss or disclose any unpublished information with those who are not present at the meeting or those who are not immediate members of their lab. Such information will remain confidential until the information (1) has been published or presented publicly or (2) the speaker has given permission to discuss the information.
 
Research Videos
Our Scientists

Our research laboratories are led by the best and brightest minds in scientific research.
 

Research Shared Services

City of Hope embodies the spirit of scientific collaboration by sharing services and core facilities with colleagues here and around the world.
 

Technology & Licensing
The Center for Applied Technology Development offers broad expertise in
technology transfer and licensing, biologics manufacturing, quality assurance and regulatory affairs.

City of Hope offers a number of exciting fellowships and residencies in laboratory research, administration, clinical applications and other areas.
NEWS & UPDATES
  • Ryan Chavira was a senior in high school when she began feeling sluggish, fatigued and, well, “down.” Trips to the doctor ended in “you’re fine” pronouncements; blood tests results showed nothing of real concern. But Chavira’s grandmother had passed away from ovarian cancer when she was in eig...
  • Brain tumors are exceptionally difficult to treat. They can be removed surgically, but individual cancer cells may have already spread elsewhere in the brain and can escape the effects of both radiation and chemotherapy. To prevent tumors from recurring, doctors need a way to find and stop those invasive cancer...
  • Breast cancer risk is personal; breast cancer risk assessment should be, too. To that end, City of Hope researchers have developed a starting point to help women (and their doctors) with a family history of the disease begin that risk assessment process. The result is an iPhone app, called BRISK, for Breast Can...
  • When it comes to breast cancer, women aren’t limited to getting screened and, if diagnosed, making appropriate treatment choices. They can also take a proactive stance in the fight against breast cancer by understanding key risk factors and practicing lifestyle habits that can help reduce their own breast...
  • Cancers of the blood and immune system are considered to be among the most difficult-to-treat cancers. A world leader in the treatment of blood cancers, City of Hope is now launching an institute specifically focused on treating people with lymphoma, leukemia and myeloma, as well as other serious blood and bone...
  • Genetics, genes, genome, genetic risk … Such terms are becoming increasingly familiar to even nonresearchers as studies and information about the human make-up become more extensive and more critical. At City of Hope, these words have long been part of our vocabulary. Researchers and physicians are studyi...
  • Mammograms are currently the best method to detect breast cancer early, when it’s easier to treat and before it’s big enough to feel or cause symptoms. But recent mammogram screening guidelines may have left some women confused about when to undergo annual testing. Here Lusi Tumyan, M.D., chief of t...
  • Although chemotherapy can be effective in treating cancer, it can also exact a heavy toll on a patient’s health. One impressive alternative researchers have found is in the form of a vaccine. A type of immunotherapy, one part of the vaccine primes the body to react strongly against a tumor; the second part dire...
  • The breast cancer statistic is attention-getting: One in eight women will be diagnosed with breast cancer during her lifetime. That doesn’t mean that, if you’re one of eight women at a dinner table, one of you is fated to have breast cancer (read more on that breast cancer statistic), but it does mean that the ...
  • Rob Darakjian was diagnosed with acute lymphoblastic leukemia at just 19 years old. He began chemotherapy and was in and out of the hospital for four months. After his fourth round of treatment, he received a bone marrow transplantation from an anonymous donor. Today, he’s cancer free. In his first post, ...
  • Advanced age tops the list among breast cancer risk factor for women. Not far behind is family history and genetics. Two City of Hope researchers delving deep into these issues recently received important grants to advance their studies. Arti Hurria, M.D., director of the Cancer and Aging Research Program, and ...
  • City of Hope is extending the reach of its lifesaving mission well beyond U.S. borders. To that end, three distinguished City of Hope leaders visited China earlier this year to lay the foundation for the institution’s new International Medicine Program. The program is part of City of Hope’s strategi...
  • A hallmark of cancer is that it doesn’t always limit itself to a primary location. It spreads. Breast cancer and lung cancer in particular are prone to spread, or metastasize, to the brain. Often the brain metastasis isn’t discovered until years after the initial diagnosis, just when patients were beginning to ...
  • Blueberries, cinnamon, baikal scullcap, grape seed extract (and grape skin extract), mushrooms, barberry, pomegranates … all contain compounds with the potential to treat, or prevent, cancer. Scientists at City of Hope have found tantalizing evidence of this potential and are determined to explore it to t...
  • Most women who are treated for breast cancer with a mastectomy do not choose to undergo reconstructive surgery. The reasons for this, according to a recent JAMA Surgery study, vary. Nearly half say they do not want any additional surgery, while nearly 34 percent say breast cancer reconstruction simply isn’t imp...