Services and Equipment
Services
The Nuclear Magnetic Resonance core manager acquires routine 1D and 2D NMR spectra for the occasional user. Training courses tailored for routine users’ specific needs are provided by the facility manager. The facility manager is also available for help with setting up NMR experiments and assistance with software related to NMR data processing and analysis.
 
Equipment
 
600 MHz Bruker Avance NMR Instrument
The 600 MHz Bruker Avance NMR instrument is equipped with four channels, a TXI cryo-probe, and a room temperature probe. This instrument is mainly used for biomolecular characterization.
   
500 MHz NMR Instrument
The 500 MHz NMR instrument has a refurbished 500 MHz Oxford magnet equipped with a Bruker Avance console. This instrument is equipped with three different probes and an auto-sample changer. The automatic sample changer holds up to 24 samples for sequential automated data collection. The broadband observe probe (BBO) has a broadband coil tunable from 109Ag to 31P, including an actively shielded Z-gradient coil. The BBO probe is ideal for direct observation of nuclei other than 1H. The micro triple resonance (1H/13C/15N) probe is ideal for natural product characterization. The active volume of the probe is 2.5 μl, and the optimal sample volume is 5 μl. The third probe is a triple resonance (1H/13C/15N) probe with triple-axis gradients for biomolecular study. The instrument is used to characterize organic compounds, natural products, and also has the capability for use in biomolecular structural studies.

 
Both 500 and 600 MHz instruments have pulse-shaping capability on three channels and have 2H decoupling capabilities. Both NMR instruments are equipped with HP PC workstations running the Linux operating system. The xwinnmr version 3.5 is used to operate the NMR instruments.