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Start-Up Guide

Getting Started
Starting a life science company from your research is certainly not for the faint of heart. It is not uncommon for a life science entrepreneur to work 80-120 hours per week. Furthermore, the entrepreneur must wear several different “hats”, including the hat of a scientist, executive decision-maker and janitor. There is a significant amount of risk associated with starting a life science company around your research; however, with great risk comes the potential for great reward. The OTL is here to guide you through the earliest stages of your company and discuss the various options and resources available to the aspiring life science entrepreneur.

Laying the Groundwork
Building a solid foundation is essential for a start-up company. This includes writing a business plan, developing the appropriate legal structure for the start-up company and hiring the right people. The OTL can put you in touch with the right resources and people to start the process. Finding ample and affordable wet lab space can also present a challenge for a burgeoning life science start-up company. Fortunately, the OTL has fostered relationships with several local incubators that offer wet lab space at a reasonable cost. Please follow the links provided or contact the OTL for more information.

Conflict of Interest
If you plan to maintain your position and tenure as a City of Hope employee while creating your start-up company, you must first present your case to the City of Hope Conflict of Interest (COI) committee. The purpose and goal of the COI committee is to identify ways to facilitate the start of a new company while managing any conflicts it may present vis-à-vis your duties as a City of Hope employee. The OTL can direct you to the appropriate COI committee members when you and your company are ready.

Raising Capital
One of the most difficult challenges faced by aspiring life science companies is finding and securing adequate funding. A start-up company should consider all options, including the “3 Fs” (friends, family and fools), private angel or venture capital investors, institutional investors, pharmaceutical company-based investment funds and even government-based, non-diluting grants such as those offered through the SBIR (Small Business Innovation Research) program. The amount of funding available from any investor will be limited, which requires investors to choose very carefully in which companies they invest. The burden of convincing investors that a company represents a solid investment opportunity falls squarely on the entrepreneur. The OTL is here to connect you to the appropriate people and organizations when the company is ready for a “pitch” to investors.

Building a Team
A successful company must assemble a team of high caliber, highly energetic individuals to perform key tasks and manage operations, including a CEO and COO. A talented and reliable attorney is an invaluable asset to a life science start-up. Forming a scientific advisory board is a good idea to guide the scientific direction of the company in its nascent stages. Having the right people on the scientific advisory board can tremendously improve visibility and focus the scientific efforts of the company. The latter is especially important at the earliest stages of a company’s development.

Entrepreneurs Corner

Start-Up Guide

Getting Started
Starting a life science company from your research is certainly not for the faint of heart. It is not uncommon for a life science entrepreneur to work 80-120 hours per week. Furthermore, the entrepreneur must wear several different “hats”, including the hat of a scientist, executive decision-maker and janitor. There is a significant amount of risk associated with starting a life science company around your research; however, with great risk comes the potential for great reward. The OTL is here to guide you through the earliest stages of your company and discuss the various options and resources available to the aspiring life science entrepreneur.

Laying the Groundwork
Building a solid foundation is essential for a start-up company. This includes writing a business plan, developing the appropriate legal structure for the start-up company and hiring the right people. The OTL can put you in touch with the right resources and people to start the process. Finding ample and affordable wet lab space can also present a challenge for a burgeoning life science start-up company. Fortunately, the OTL has fostered relationships with several local incubators that offer wet lab space at a reasonable cost. Please follow the links provided or contact the OTL for more information.

Conflict of Interest
If you plan to maintain your position and tenure as a City of Hope employee while creating your start-up company, you must first present your case to the City of Hope Conflict of Interest (COI) committee. The purpose and goal of the COI committee is to identify ways to facilitate the start of a new company while managing any conflicts it may present vis-à-vis your duties as a City of Hope employee. The OTL can direct you to the appropriate COI committee members when you and your company are ready.

Raising Capital
One of the most difficult challenges faced by aspiring life science companies is finding and securing adequate funding. A start-up company should consider all options, including the “3 Fs” (friends, family and fools), private angel or venture capital investors, institutional investors, pharmaceutical company-based investment funds and even government-based, non-diluting grants such as those offered through the SBIR (Small Business Innovation Research) program. The amount of funding available from any investor will be limited, which requires investors to choose very carefully in which companies they invest. The burden of convincing investors that a company represents a solid investment opportunity falls squarely on the entrepreneur. The OTL is here to connect you to the appropriate people and organizations when the company is ready for a “pitch” to investors.

Building a Team
A successful company must assemble a team of high caliber, highly energetic individuals to perform key tasks and manage operations, including a CEO and COO. A talented and reliable attorney is an invaluable asset to a life science start-up. Forming a scientific advisory board is a good idea to guide the scientific direction of the company in its nascent stages. Having the right people on the scientific advisory board can tremendously improve visibility and focus the scientific efforts of the company. The latter is especially important at the earliest stages of a company’s development.

Entrepreneurs Bookshelf

Overview
Office of Technology Licensing
City of Hope
1500 E. Duarte Rd.
Modular 101
Duarte, CA 91010
 
 
 
Center for Applied Technology Development (CATD)
The Sylvia R. and Isador A. Deutch Center for Applied Technology Development (CATD) offers broad expertise in technology transfer and licensing, biologics manufacturing, quality assurance and regulatory affairs.

City of Hope Campus Map
 
 
 
 
City of Hope is one of only 41 Comprehensive Cancer Centers in the country, the highest designation awarded by the National Cancer Institute to institutions that lead the way in cancer research, treatment, prevention and professional education.
Beckman Research Institute of City of Hope is internationally  recognized for its innovative biomedical research.
Learn more about City of Hope's institutional distinctions, breakthrough innovations and collaborations.


NEWS & UPDATES
  • The lack of a practical way to produce and store enough stem cells for larger-scale therapies and clinical trials is creating a bottleneck in stem cell research. A new grant to City of Hope from the California Institute for Regenerative Medicine will help solve that problem. The $899,728 grant, awarded Thursday...
  • City of Hope has long known what researchers increasingly are confirming: Gardens and natural surroundings help seriously ill people recover from their treatment ordeals. Already a trailblazer in the creation of beautiful natural spaces for cancer patients and their families, on Jan. 15,  City of Hope dedicated...
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  • We’ve seen it in science fiction: The aliens begin terra-forming a planet to create a friendly habitat that gives them, not the inhabitants, all the advantages when the colonization begins. Turns out, cancer does essentially the same thing when it metastasizes, according to new research from City of Hope. The f...
  • Equipping the immune system to fight cancer – a disease that thrives on mutations and circumventing the body’s natural defenses – is within reach. In fact, City of Hope researchers are testing one approach in clinical trials now. Scientists take a number of steps to turn cancer patients’ T cells – white b...
  • As treatments for lung cancer become more targeted and effective, the need for better technology to detect lung cancer mutations becomes increasingly important. A new clinical study at City of Hope is examining the feasibility of using blood and urine tests to detect lung cancer mutations, potentially allowing ...
  • When it comes to breast cancer risk, insulin levels may matter more than weight, new research has found. The study from Imperial College London School of Public Health, published in the journal Cancer Research, indicates that metabolic health – not a person’s weight or body mass index – increases breast cancer ...
  • No one ever plans to have cancer – and there’s never a good time. For Homa Sadat, her cancer came at a particularly bad time: just one year after losing her father to the pancreatic cancer he had battled for two years. She was working a grueling schedule managing three commercial office buildings. She’d just [&...
  • Patients at City of Hope – most of whom are fighting cancer – rely on more than 37,000 units of blood and platelets each year for their treatment and survival. Every one of those units comes from family, friends or someone who traded an hour or so of their time and a pint of their […]
  • Surgery is vital in the treatment of cancer – it’s used to help diagnose, treat and even prevent the disease – so a new colorectal cancer study linking a decrease in surgeries for advanced cancer to increased survival rates may raise more questions than it answers for some patients. The surgery-and-surviv...
  • Age is the single greatest risk factor overall for cancer; our chances of developing the disease rise steeply after age 50. For geriatric oncology nurse Peggy Burhenn, the meaning is clear: Cancer is primarily a geriatric condition. That’s why she is forging inroads in the care of older adults with cancer. Burh...
  • One of American’s great sportscasters, Stuart Scott, passed away from recurrent cancer of the appendix at the young age of 49. His cancer was diagnosed when he was only 40 years old. It was found during an operation for appendicitis. His courageous fight against this disease began in 2007, resumed again with an...
  • When Homa Sadat found a lump in her breast at age 27, her gynecologist told her what many doctors say to young women: You’re too young to have breast cancer. With the lump dismissed as a harmless cyst, she didn’t think about it again until she was at a restaurant six months later and felt […]
  • What most people call a “bone marrow transplant” is not actually a transplant of bone marrow; it is instead the transplantation of what’s known as hematopoietic stem cells. Such cells are often taken from bone marrow, but not always. Hematopoietic stem cells are simply immature cells that can ...
  • Doctors have long known that women with a precancerous condition called atypical hyperplasia have an elevated risk of breast cancer. Now a new study has found that the risk is more serious than previously thought. Hyperplasia itself is an overgrowth of cells; atypical hyperplasia is an overgrowth in a distorted...