A National Cancer Institute-designated Comprehensive Cancer Center

Make an appointment: 800-826-HOPE
Entrepreneurs Corner Bookmark and Share

Start-Up Guide

Getting Started
Starting a life science company from your research is certainly not for the faint of heart. It is not uncommon for a life science entrepreneur to work 80-120 hours per week. Furthermore, the entrepreneur must wear several different “hats”, including the hat of a scientist, executive decision-maker and janitor. There is a significant amount of risk associated with starting a life science company around your research; however, with great risk comes the potential for great reward. The OTL is here to guide you through the earliest stages of your company and discuss the various options and resources available to the aspiring life science entrepreneur.

Laying the Groundwork
Building a solid foundation is essential for a start-up company. This includes writing a business plan, developing the appropriate legal structure for the start-up company and hiring the right people. The OTL can put you in touch with the right resources and people to start the process. Finding ample and affordable wet lab space can also present a challenge for a burgeoning life science start-up company. Fortunately, the OTL has fostered relationships with several local incubators that offer wet lab space at a reasonable cost. Please follow the links provided or contact the OTL for more information.

Conflict of Interest
If you plan to maintain your position and tenure as a City of Hope employee while creating your start-up company, you must first present your case to the City of Hope Conflict of Interest (COI) committee. The purpose and goal of the COI committee is to identify ways to facilitate the start of a new company while managing any conflicts it may present vis-à-vis your duties as a City of Hope employee. The OTL can direct you to the appropriate COI committee members when you and your company are ready.

Raising Capital
One of the most difficult challenges faced by aspiring life science companies is finding and securing adequate funding. A start-up company should consider all options, including the “3 Fs” (friends, family and fools), private angel or venture capital investors, institutional investors, pharmaceutical company-based investment funds and even government-based, non-diluting grants such as those offered through the SBIR (Small Business Innovation Research) program. The amount of funding available from any investor will be limited, which requires investors to choose very carefully in which companies they invest. The burden of convincing investors that a company represents a solid investment opportunity falls squarely on the entrepreneur. The OTL is here to connect you to the appropriate people and organizations when the company is ready for a “pitch” to investors.

Building a Team
A successful company must assemble a team of high caliber, highly energetic individuals to perform key tasks and manage operations, including a CEO and COO. A talented and reliable attorney is an invaluable asset to a life science start-up. Forming a scientific advisory board is a good idea to guide the scientific direction of the company in its nascent stages. Having the right people on the scientific advisory board can tremendously improve visibility and focus the scientific efforts of the company. The latter is especially important at the earliest stages of a company’s development.

Entrepreneurs Corner

Start-Up Guide

Getting Started
Starting a life science company from your research is certainly not for the faint of heart. It is not uncommon for a life science entrepreneur to work 80-120 hours per week. Furthermore, the entrepreneur must wear several different “hats”, including the hat of a scientist, executive decision-maker and janitor. There is a significant amount of risk associated with starting a life science company around your research; however, with great risk comes the potential for great reward. The OTL is here to guide you through the earliest stages of your company and discuss the various options and resources available to the aspiring life science entrepreneur.

Laying the Groundwork
Building a solid foundation is essential for a start-up company. This includes writing a business plan, developing the appropriate legal structure for the start-up company and hiring the right people. The OTL can put you in touch with the right resources and people to start the process. Finding ample and affordable wet lab space can also present a challenge for a burgeoning life science start-up company. Fortunately, the OTL has fostered relationships with several local incubators that offer wet lab space at a reasonable cost. Please follow the links provided or contact the OTL for more information.

Conflict of Interest
If you plan to maintain your position and tenure as a City of Hope employee while creating your start-up company, you must first present your case to the City of Hope Conflict of Interest (COI) committee. The purpose and goal of the COI committee is to identify ways to facilitate the start of a new company while managing any conflicts it may present vis-à-vis your duties as a City of Hope employee. The OTL can direct you to the appropriate COI committee members when you and your company are ready.

Raising Capital
One of the most difficult challenges faced by aspiring life science companies is finding and securing adequate funding. A start-up company should consider all options, including the “3 Fs” (friends, family and fools), private angel or venture capital investors, institutional investors, pharmaceutical company-based investment funds and even government-based, non-diluting grants such as those offered through the SBIR (Small Business Innovation Research) program. The amount of funding available from any investor will be limited, which requires investors to choose very carefully in which companies they invest. The burden of convincing investors that a company represents a solid investment opportunity falls squarely on the entrepreneur. The OTL is here to connect you to the appropriate people and organizations when the company is ready for a “pitch” to investors.

Building a Team
A successful company must assemble a team of high caliber, highly energetic individuals to perform key tasks and manage operations, including a CEO and COO. A talented and reliable attorney is an invaluable asset to a life science start-up. Forming a scientific advisory board is a good idea to guide the scientific direction of the company in its nascent stages. Having the right people on the scientific advisory board can tremendously improve visibility and focus the scientific efforts of the company. The latter is especially important at the earliest stages of a company’s development.

Entrepreneurs Bookshelf

Overview
Office of Technology Licensing
City of Hope
1500 E. Duarte Rd.
Modular 101
Duarte, CA 91010
 
 
 
Center for Applied Technology Development (CATD)
The Sylvia R. and Isador A. Deutch Center for Applied Technology Development (CATD) offers broad expertise in technology transfer and licensing, biologics manufacturing, quality assurance and regulatory affairs.

City of Hope Campus Map
 
 
 
 
City of Hope is one of only 41 Comprehensive Cancer Centers in the country, the highest designation awarded by the National Cancer Institute to institutions that lead the way in cancer research, treatment, prevention and professional education.
Beckman Research Institute of City of Hope is internationally  recognized for its innovative biomedical research.
Learn more about City of Hope's institutional distinctions, breakthrough innovations and collaborations.


NEWS & UPDATES
  • As far back as he can remember, Jonathan Yamzon, M.D., wanted to be a doctor. “I knew it from the get-go,” he said, matter-of-factly. “I always envisioned it as the ideal; the supreme thing one could do with one’s life.” The youngest of six children, Yamzon was barely a toddler when his family moved to [&...
  • There’s never a “good” time for cancer to strike. With testicular cancer, the timing can seem particularly unfair. This disease targets young adults in the prime of life; otherwise healthy people unaccustomed to any serious illness, let alone cancer. And suddenly … “I can only imagine what they must...
  • Sure, a healthy lifestyle can lower a person’s risk, but the impact of specific actions is harder to tease out. Diet, exercise, tobacco use, nutritional supplements, alcohol consumption … How important are each of these factors, individually? Does strict adherence to (or rejection of) one get you a pass o...
  • Health care decisions are tough. They’re even tougher when you – or loved ones – have to make them without a plan or a conversation. National Healthcare Decisions Day, on April 16,  is a nationwide initiative to demystify the health care decision-making process and encourage families to start talking. Ult...
  • The statistics, direct from the American Cancer Society, are sobering: Cancer death rates among African-American men are 27 percent higher than for white men. The death rate for African-American women is 11 percent higher compared to white women. Hispanics have higher rates of cervical, liver and stomach cancer...
  • “Lucky” is not usually a term used to describe someone diagnosed with cancer.  But that’s how 34-year-old Alex Camargo’s doctor described him when he was diagnosed with thyroid cancer — the disease is one of the most treatable cancers at all stages. That doctor was ultimately proved righ...
  • Geoff Berman, 61, starts his day with the motto: “The sun is up. I’m vertical. It’s a good day.” Ever since he’s been in remission from lymphoma, Berman makes a special point of being grateful for each day, reminding himself that being alive is a gift. “I just enjoy living,” he said. “I give e...
  • Neural stem cells have a natural ability to seek out cancer cells in the brain. Recent research from the laboratories of Michael Barish, Ph.D., and Karen Aboody, M.D., may offer a new explanation for this attraction between stem cells and tumors. Prior to joining City of Hope, Aboody, now a professor in the Dep...
  • The American Society of Clinical Oncology, a group that includes more than 40,000 cancer specialists around the country, recently issued a list of the five most profound cancer advances over the past five decades. Near the top of the list was the introduction of chemotherapy for testicular cancer. To many in th...
  • “The dying, as a group, have been horribly underserved.” So says Bonnie Freeman, R.N., D.N.P., A.N.P.-B.C., A.C.H.P.N., a nurse practitioner in the Department of Supportive Care Medicine at City of Hope. After nearly 25 years, primarily in critical care nursing, Freeman saw that the needs of the dying were ofte...
  • “Are we the only ones who feel this way?” Courtney Bitz, L.C.S.W., a social worker in the Sheri & Les Biller Patient and Family Resource Center at City of Hope, often hears this question from couples trying to cope with a breast cancer diagnosis and still keep their relationship strong. The ques...
  • Diabetes investigators at City of Hope are studying the full trajectory of diabetes and metabolic disorders, as well as complications of the disease. One especially promising approach focuses on proteins known as growth factors. Led by Fouad Kandeel, M.D., Ph.D., chair and professor of the Department of Clinica...
  • Acute myeloid leukemia is the most common form of acute leukemia among adults, accounting for 18,000 diagnoses in 2014. Two decades ago, in 1996, the National Comprehensive Cancer Network (NCCN) published its first guidelines for treatment of acute myeloid leukemia, or AML. Margaret O’Donnell, M.D., assoc...
  • Children diagnosed with cancer are more likely than ever before to survive the disease, but with a potential new set of health problems caused by the cancer treatment itself. Those problems can particularly affect the heart, and as doctors and other health care workers try to assess how best to care for this sp...
  • Karen Reckamp, M.D., M.S., has an office next to my own, and we often see patients at the same time. As such, I’ve gotten to know her quite well over the years, and I’ve also gotten a glimpse of many of her patients. She specializes in lung cancer, and most of her patients have tumors […]