A National Cancer Institute-designated Comprehensive Cancer Center

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Pediatric Brain and Spinal Tumors

City of Hope offers comprehensive, family-centered, leading -edge treatment for children, adolescents and young adults (AYA) with malignant and benign tumors of the brain and spinal cord.

For nearly two decades, City of Hope has provided life-saving treatments by bringing basic laboratory research to the patient’s bedside. Gene therapy and stem cell therapy trials are being developed by City of Hope researchers to treat some of the deadliest forms of brain cancer. City of Hope is also a member of the Children’s Oncology Group (COG), which provides access to the nation’s largest group of pediatric and adolescent clinical trials. In addition, our team of neurosurgeons offers world-class neurosurgical techniques for tumors of both brain and spine. City of Hope was also the first hospital in Southern California to provide Helical TomoTherapy, which dramatically decreases the side effects of radiation treatment.
 
Our board-certified experts in pediatric oncology, radiation therapy and neurosurgery provide treatment for a wide variety of brain and spine tumors including:

  • Glioblastoma multiformae
  • Medulloblastoma/primitive neuroectodermal tumor
  • Brain stem glioma
  • Astrocytoma
  • Retinoblastoma
  • Ependymoma
  • Optic glioma
  • Germ cell tumors of the brain and spine
  • Rare brain tumors
  • Childhood and young adult tumors that have metastasized to the brain
     
Patients with brain and spinal tumors require a team of professionals to provide comprehensive and family-centered care. The City of Hope team includes social workers; child-life specialists; recreation, occupational and physical rehabilitation specialists; school reintegration specialists; nutritionists; psychologists; neuropsychologists; and spiritual-care specialists.

Members of our team:
 
In addition to the best medical care available, City of Hope also provides patients and their families access to several programs that include:
 
  • The Biller Patient and Family Resource Center
  • Unique support programs for adolescents and young adults (AYA) to assist with the often difficult transition into adulthood at the time of illness
  • Late effects/survivor clinic follows patients long after their treatment to identify, treat and counsel for any issue that can arise related to their life-saving treatment
     
City of Hope physicians are leading research to find better treatments for children, adolescents and young adults with brain and spinal tumors. For more information on our pediatric cancer research, including ongoing trials, visit City of Hope’s Clinical Trials Online website.
 

Pediatric Brain and Spinal Tumors

Pediatric Brain and Spinal Tumors

City of Hope offers comprehensive, family-centered, leading -edge treatment for children, adolescents and young adults (AYA) with malignant and benign tumors of the brain and spinal cord.

For nearly two decades, City of Hope has provided life-saving treatments by bringing basic laboratory research to the patient’s bedside. Gene therapy and stem cell therapy trials are being developed by City of Hope researchers to treat some of the deadliest forms of brain cancer. City of Hope is also a member of the Children’s Oncology Group (COG), which provides access to the nation’s largest group of pediatric and adolescent clinical trials. In addition, our team of neurosurgeons offers world-class neurosurgical techniques for tumors of both brain and spine. City of Hope was also the first hospital in Southern California to provide Helical TomoTherapy, which dramatically decreases the side effects of radiation treatment.
 
Our board-certified experts in pediatric oncology, radiation therapy and neurosurgery provide treatment for a wide variety of brain and spine tumors including:

  • Glioblastoma multiformae
  • Medulloblastoma/primitive neuroectodermal tumor
  • Brain stem glioma
  • Astrocytoma
  • Retinoblastoma
  • Ependymoma
  • Optic glioma
  • Germ cell tumors of the brain and spine
  • Rare brain tumors
  • Childhood and young adult tumors that have metastasized to the brain
     
Patients with brain and spinal tumors require a team of professionals to provide comprehensive and family-centered care. The City of Hope team includes social workers; child-life specialists; recreation, occupational and physical rehabilitation specialists; school reintegration specialists; nutritionists; psychologists; neuropsychologists; and spiritual-care specialists.

Members of our team:
 
In addition to the best medical care available, City of Hope also provides patients and their families access to several programs that include:
 
  • The Biller Patient and Family Resource Center
  • Unique support programs for adolescents and young adults (AYA) to assist with the often difficult transition into adulthood at the time of illness
  • Late effects/survivor clinic follows patients long after their treatment to identify, treat and counsel for any issue that can arise related to their life-saving treatment
     
City of Hope physicians are leading research to find better treatments for children, adolescents and young adults with brain and spinal tumors. For more information on our pediatric cancer research, including ongoing trials, visit City of Hope’s Clinical Trials Online website.
 
Patient Care Overview

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Meet City of Hope patients and their families.
 
 
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As a Comprehensive Cancer Center – the highest designation given by the National Cancer Institute – we are widely regarded as a leader in cancer prevention and treatment.

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NEWS & UPDATES
  • Think twice before tossing out those hormone replacement pills. Although a new Lancet study suggests that hormone replacement therapy could increase a woman’s risk of ovarian cancer, a City of Hope expert urges women to keep this news in perspective. Hormone replacement therapy is prescribed to help allev...
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  • The spinal cord is an integral part of the human body, connecting the brain to everything else. So when a tumor grows on the spine, any messages that the brain tries to send to the rest of the body are interrupted, making everyday tasks — such as walking — more difficult. This year an estimated 22,850 […]
  • Each year, thousands of patients with hematologic malignancies undergo allogeneic stem cell transplantation (that is, they receive a donor’s stem cells), offering them a chance at cure. Graft-versus-host disease is a potentially deadly complication of this therapy and occurs in approximately 25 to 60 perc...
  • Bertram Yuh, M.D., assistant clinical professor in the Division of Urology and Urologic Oncology at City of Hope, offers his perspective on the benefits of surgery for aggressive prostate cancer. For men walking out of the doctor’s office after a diagnosis of cancer, the reality can hit like a ton of bricks. Th...
  • Although many Hispanic women face a high risk of mutations in the BRCA1 and BRCA2 genes – increasing their risk of breast and ovarian cancer – screenings for these mutations can be prohibitively expensive in Mexico and other Latin American countries. As a result, too many women don’t get the information t...
  • Providing lung cancer treatments to patients when their cancer is at its earliest and most treatable stages will now be a more attainable goal: Medicare has agreed to cover lung cancer screening for those beneficiaries who meet the requirements. The only proven way to detect lung cancer early enough to save liv...
  • At City of Hope, innovative scientific research, important clinical studies and vital construction projects are all powered by philanthropy. Generous supporters fuel a powerful and diverse range of progress in science and medicine, enabling researchers and clinicians to improve cancer treatments and create cure...
  • Trevor Hoffman was only 21 when he was diagnosed with a rare form of cancer, but not even cancer could keep him off his motorcycles. (He has one for racing, and a couple just for fun.) Now a cancer survivor, Hoffman, who lives in La Verne, California, wrapped up his treatment Jan. 19 – just one day […]
  • Valentine’s Day is synonymous with dinner reservations, red roses, heart-shaped boxes of chocolates and — more often than not — unrealistically high expectations. Managing those expectations is great advice for all couples on Feb. 14 — and is especially important for couples confronting a cancer diagnosis. Focu...
  • With measles, what starts at a theme park in California definitely doesn’t stay at a theme park in California. Since the beginning of the current measles outbreak – traced to an initial exposure at Disneyland or Disney California Adventure during December – more than 100 people have been diagnosed with a diseas...
  • Even the most loving and secure relationship can be rattled by a life-threatening illness. When a woman is diagnosed with breast cancer, research shows one of the most important factors in helping her cope is having a supportive partner. But that partner can struggle with knowing what to say or how to best supp...
  • It’s been more than a century since Nobel Laureate Paul Ehrlich popularized the idea of a “magic bullet” targeting disease. Cancer researchers ever since have remained in hot pursuit of targeted therapies that home in on cancer cells while leaving normal cells unaffected. Linda Malkas, Ph.D., associate chair of...
  • Cancer patients face a daunting journey marked by challenges and uncertainties. For those undergoing bone marrow, or stem cell, transplantation, one complication poses a particular threat — chronic graft-versus-host disease (GVHD). Now, one researcher may have found a better way to control that threat. GVHD res...