A National Cancer Institute-designated Comprehensive Cancer Center

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Leukemia and Lymphoma Programs

At City of Hope, our team of pediatric experts provides comprehensive care for children with leukemia and lymphoma. Leukemia is a cancer of the blood and the most common cancer in children, accounting for approximately 40 percent of all cancer diagnoses in children. Lymphomas are cancers that develop in the body’s lymphatic system and are the third most common pediatric cancer, after leukemia and brain tumors. Our program treats patients with a range of leukemias and lymphomas, including:

Leukemias
 
  • Acute lymphoblastic leukemia (ALL)
  • Acute myeloid leukemia (AML)
  • Chronic myelogenous leukemia (CML)
     
Lymphomas
 
  • Hodgkin lymphoma
  • Non-Hodgkin lymphoma
    • Anaplastic large-cell lymphoma (ALCL)
    • B-cell lymphoma (Burkitt and Burkitt-like lymphoma)
    • Diffuse large B-cell lymphoma (DLBC)
    • Lymphoblastic lymphoma
    • T-cell lymphoma
    • MK-cell lymphoma
       
We treat newly diagnosed patients, as well as patients referred to us from other centers who come to City of Hope to continue their treatment, manage complications of treatment or develop new treatment strategies for cancers not responding to treatment, or for situations in which they have experienced a relapse. For children who fail to respond to treatment or experience a relapse, City of Hope has a renowned program in stem cell transplantation, as well as ongoing studies into novel therapies for relapsed/refractory leukemia.
 
Each type of childhood cancer is treated differently, based on what has been found to be most effective in destroying the particular type of cancer cell. The most common type of cancer treatment for leukemia and lymphoma is chemotherapy. In some cases, radiation therapy and/or stem cell transplant may be recommended. Immunotherapy, or treatment that uses certain parts of the immune system to fight cancer, may be used as well.

A unique benefit of being treated at City of Hope is that we treat young children, adolescents and young adults, ensuring a continuum of care through the years for this special group of patients. Adolescents and young adults may be eligible for clinical studies and novel treatments available for adult patients at City of Hope, while still benefitting from the patient and family-centered approach of the pediatric program.

Our program offers both outstanding medical treatment and psychosocial support to young cancer patients and their family members. Pediatric oncologists, hematologists, surgeons, radiation oncologists, pathologists and other specialists work in concert to develop a targeted, effective treatment plan.  At the same time, professionals in psychology; social work; child life; recreational, occupational and physical therapy; music therapy; and school reintegration provide individual attention and group activities for patients and their families.

Meet the members of City of Hope’s pediatric leukemia and lymphoma team:
 
The majority of children diagnosed with leukemia or lymphoma are cured; however, there can be long-term side effects. Our Center for Cancer Survivorship clinic is specially designed to meet the follow-up needs of childhood cancer survivors, who are evaluated annually by a team of health care professionals with expertise in survivorship issues.
 
Your child may have the opportunity to participate in a research study or clinical trial through our participation in the Children’s Oncology Group (COG) and our designation as one of only 41 National Cancer Institute (NCI) Comprehensive Cancer Centers in the U.S. More information about our pediatric cancer research, including ongoing clinical trials, is available on City of Hope’s Clinical Trials Online website.
 

Leukemia and Lymphoma

Leukemia and Lymphoma Programs

At City of Hope, our team of pediatric experts provides comprehensive care for children with leukemia and lymphoma. Leukemia is a cancer of the blood and the most common cancer in children, accounting for approximately 40 percent of all cancer diagnoses in children. Lymphomas are cancers that develop in the body’s lymphatic system and are the third most common pediatric cancer, after leukemia and brain tumors. Our program treats patients with a range of leukemias and lymphomas, including:

Leukemias
 
  • Acute lymphoblastic leukemia (ALL)
  • Acute myeloid leukemia (AML)
  • Chronic myelogenous leukemia (CML)
     
Lymphomas
 
  • Hodgkin lymphoma
  • Non-Hodgkin lymphoma
    • Anaplastic large-cell lymphoma (ALCL)
    • B-cell lymphoma (Burkitt and Burkitt-like lymphoma)
    • Diffuse large B-cell lymphoma (DLBC)
    • Lymphoblastic lymphoma
    • T-cell lymphoma
    • MK-cell lymphoma
       
We treat newly diagnosed patients, as well as patients referred to us from other centers who come to City of Hope to continue their treatment, manage complications of treatment or develop new treatment strategies for cancers not responding to treatment, or for situations in which they have experienced a relapse. For children who fail to respond to treatment or experience a relapse, City of Hope has a renowned program in stem cell transplantation, as well as ongoing studies into novel therapies for relapsed/refractory leukemia.
 
Each type of childhood cancer is treated differently, based on what has been found to be most effective in destroying the particular type of cancer cell. The most common type of cancer treatment for leukemia and lymphoma is chemotherapy. In some cases, radiation therapy and/or stem cell transplant may be recommended. Immunotherapy, or treatment that uses certain parts of the immune system to fight cancer, may be used as well.

A unique benefit of being treated at City of Hope is that we treat young children, adolescents and young adults, ensuring a continuum of care through the years for this special group of patients. Adolescents and young adults may be eligible for clinical studies and novel treatments available for adult patients at City of Hope, while still benefitting from the patient and family-centered approach of the pediatric program.

Our program offers both outstanding medical treatment and psychosocial support to young cancer patients and their family members. Pediatric oncologists, hematologists, surgeons, radiation oncologists, pathologists and other specialists work in concert to develop a targeted, effective treatment plan.  At the same time, professionals in psychology; social work; child life; recreational, occupational and physical therapy; music therapy; and school reintegration provide individual attention and group activities for patients and their families.

Meet the members of City of Hope’s pediatric leukemia and lymphoma team:
 
The majority of children diagnosed with leukemia or lymphoma are cured; however, there can be long-term side effects. Our Center for Cancer Survivorship clinic is specially designed to meet the follow-up needs of childhood cancer survivors, who are evaluated annually by a team of health care professionals with expertise in survivorship issues.
 
Your child may have the opportunity to participate in a research study or clinical trial through our participation in the Children’s Oncology Group (COG) and our designation as one of only 41 National Cancer Institute (NCI) Comprehensive Cancer Centers in the U.S. More information about our pediatric cancer research, including ongoing clinical trials, is available on City of Hope’s Clinical Trials Online website.
 
Patient Care Overview

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Cancer Care
For the 11th year, U.S.News & World Report has named City of Hope one of the top cancer hospitals in the country.
NEWS & UPDATES
  • Although a stem cell transplant can be a lifesaving procedure for people diagnosed with a blood cancer or blood disorder, the standard transplant may not be appropriate for all patients. This is because the conditioning regimen (the intensive chemotherapy and/or radiation treatments preceding the transplant) is...
  • Brain tumor removal would seem to be the obvious course of action in the wake of a brain tumor diagnosis, but that’s not always the case. Some tumors are too difficult for many surgeons to reach or too close to areas that control vital functions. Removing them just proves too risky. A new device at City [...
  • Hijacking the same sorts of viruses that cause HIV and using them to reprogram immune cells to fight cancer sounds like stuff of the future. Some scientists believe that the future is closer than we think – and are now studying the approach in clinical trials at City of Hope. Immunotherapy is a promising approa...
  • Nausea is the one of the most well-known, and dreaded, side effects of cancer treatment — and with good reason. Beyond the quality-of-life issues that it causes, severe nausea can prevent patients from receiving enough nutrients and calories at a time when they need every edge they can get. A few simple actions...
  • With Labor Day just around the corner, summer is on its way out. But just because summertime is ending doesn’t mean we can skip sunscreen. Protection from ultraviolet (UV) radiation is needed all year round. Exposure to UV radiation — whether from the sun or from artificial sources such as sunlamps used i...
  • Undergoing reconstructive surgery may seem like a forgone conclusion for survivors of breast cancer, but that doesn’t appear to be the case. A new study has found that most breast cancer survivors who undergo a mastectomy decide against surgical reconstruction of their breasts. The reasons for such a deci...
  • Nearly four decades ago, City of Hope began its bone marrow transplant program. Its first transplant reunion celebration was a single patient and his donor, also his brother. This year, City of Hope welcomed hundreds of hematopoietic cell transplant (HCT) recipients to the annual bone marrow transplant/HCT reun...
  • The burgeoning type 2 diabetes epidemic casts a pall over the health of America’s public. New research now shows the looming threat is getting worse. Much worse. A diabetes trends study published earlier this month in the Lancet Diabetes and Endocrinology by researchers at the federal Centers for Disease Contro...
  • An aspirin a day might help keep breast cancer away for some breast cancer survivors, a new study suggests. Obese women who have had breast cancer could cut their risk of a recurrence in half if they regularly take aspirin or other nonsteroidal anti-inflammatory drugs, called NSAIDs, report researchers from the...
  • Christine Crews isn’t only a fitness enthusiast, she’s also a personal trainer and fitness instructor. Being active defines her life. So when she was diagnosed with bladder cancer at age 30, she decided she absolutely couldn’t let the disease interfere with that lifestyle. And it didn’t. For t...
  • Cancer treatment and the cancer itself can cause changes in your sense of taste or smell. These side effects typically subside after treatment ends, but there are ways to help alleviate those bitter and metallic tastes in your mouth. Here are tips from the National Cancer Institute to help keeps tastes and food...
  • Immunotherapy — using one’s immune system to treat a disease — has been long lauded as the “magic bullet” of cancer treatments, one that can be more effective than the conventional therapies of surgery, radiation or chemotherapy. One specific type of immunotherapy, called adoptive T cell thera...
  • Today, when cancer spreads from its original site to other parts of the body, a process known as metastasis, patients face an uphill battle. Treatments are poorly effective, and cures are nearly impossible. Further, incidence rates for these types of cancers are increasing – particularly for cancers that have s...
  • Thanks to the California Institute for Regenerative Medicine (CIRM), high school students across the state gained valuable hands-on experience with stem cell research this summer. City of Hope hosted eight of those students. As part of the CIRM Creativity Awards program, the young scholars worked full time as m...
  • Radiation therapy can help cure many children facing Hodgkin lymphoma and other cancers. When the radiation is delivered to a girl’s chest, however, it can lead to a marked increase in breast cancer risk later in life. A recent multi-institutional study that included City of Hope’s Smita Bhatia, M.D., M.P.H., t...