A National Cancer Institute-designated Comprehensive Cancer Center

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Leukemia and Lymphoma Programs

At City of Hope, our team of pediatric experts provides comprehensive care for children with leukemia and lymphoma. Leukemia is a cancer of the blood and the most common cancer in children, accounting for approximately 40 percent of all cancer diagnoses in children. Lymphomas are cancers that develop in the body’s lymphatic system and are the third most common pediatric cancer, after leukemia and brain tumors. Our program treats patients with a range of leukemias and lymphomas, including:

Leukemias
 
  • Acute lymphoblastic leukemia (ALL)
  • Acute myeloid leukemia (AML)
  • Chronic myelogenous leukemia (CML)
     
Lymphomas
 
  • Hodgkin lymphoma
  • Non-Hodgkin lymphoma
    • Anaplastic large-cell lymphoma (ALCL)
    • B-cell lymphoma (Burkitt and Burkitt-like lymphoma)
    • Diffuse large B-cell lymphoma (DLBC)
    • Lymphoblastic lymphoma
    • T-cell lymphoma
    • MK-cell lymphoma
       
We treat newly diagnosed patients, as well as patients referred to us from other centers who come to City of Hope to continue their treatment, manage complications of treatment or develop new treatment strategies for cancers not responding to treatment, or for situations in which they have experienced a relapse. For children who fail to respond to treatment or experience a relapse, City of Hope has a renowned program in stem cell transplantation, as well as ongoing studies into novel therapies for relapsed/refractory leukemia.
 
Each type of childhood cancer is treated differently, based on what has been found to be most effective in destroying the particular type of cancer cell. The most common type of cancer treatment for leukemia and lymphoma is chemotherapy. In some cases, radiation therapy and/or stem cell transplant may be recommended. Immunotherapy, or treatment that uses certain parts of the immune system to fight cancer, may be used as well.

A unique benefit of being treated at City of Hope is that we treat young children, adolescents and young adults, ensuring a continuum of care through the years for this special group of patients. Adolescents and young adults may be eligible for clinical studies and novel treatments available for adult patients at City of Hope, while still benefitting from the patient and family-centered approach of the pediatric program.

Our program offers both outstanding medical treatment and psychosocial support to young cancer patients and their family members. Pediatric oncologists, hematologists, surgeons, radiation oncologists, pathologists and other specialists work in concert to develop a targeted, effective treatment plan.  At the same time, professionals in psychology; social work; child life; recreational, occupational and physical therapy; music therapy; and school reintegration provide individual attention and group activities for patients and their families.

Meet the members of City of Hope’s pediatric leukemia and lymphoma team:
 
The majority of children diagnosed with leukemia or lymphoma are cured; however, there can be long-term side effects. Our Center for Cancer Survivorship clinic is specially designed to meet the follow-up needs of childhood cancer survivors, who are evaluated annually by a team of health care professionals with expertise in survivorship issues.
 
Your child may have the opportunity to participate in a research study or clinical trial through our participation in the Children’s Oncology Group (COG) and our designation as one of only 41 National Cancer Institute (NCI) Comprehensive Cancer Centers in the U.S. More information about our pediatric cancer research, including ongoing clinical trials, is available on City of Hope’s Clinical Trials Online website.
 

Leukemia and Lymphoma

Leukemia and Lymphoma Programs

At City of Hope, our team of pediatric experts provides comprehensive care for children with leukemia and lymphoma. Leukemia is a cancer of the blood and the most common cancer in children, accounting for approximately 40 percent of all cancer diagnoses in children. Lymphomas are cancers that develop in the body’s lymphatic system and are the third most common pediatric cancer, after leukemia and brain tumors. Our program treats patients with a range of leukemias and lymphomas, including:

Leukemias
 
  • Acute lymphoblastic leukemia (ALL)
  • Acute myeloid leukemia (AML)
  • Chronic myelogenous leukemia (CML)
     
Lymphomas
 
  • Hodgkin lymphoma
  • Non-Hodgkin lymphoma
    • Anaplastic large-cell lymphoma (ALCL)
    • B-cell lymphoma (Burkitt and Burkitt-like lymphoma)
    • Diffuse large B-cell lymphoma (DLBC)
    • Lymphoblastic lymphoma
    • T-cell lymphoma
    • MK-cell lymphoma
       
We treat newly diagnosed patients, as well as patients referred to us from other centers who come to City of Hope to continue their treatment, manage complications of treatment or develop new treatment strategies for cancers not responding to treatment, or for situations in which they have experienced a relapse. For children who fail to respond to treatment or experience a relapse, City of Hope has a renowned program in stem cell transplantation, as well as ongoing studies into novel therapies for relapsed/refractory leukemia.
 
Each type of childhood cancer is treated differently, based on what has been found to be most effective in destroying the particular type of cancer cell. The most common type of cancer treatment for leukemia and lymphoma is chemotherapy. In some cases, radiation therapy and/or stem cell transplant may be recommended. Immunotherapy, or treatment that uses certain parts of the immune system to fight cancer, may be used as well.

A unique benefit of being treated at City of Hope is that we treat young children, adolescents and young adults, ensuring a continuum of care through the years for this special group of patients. Adolescents and young adults may be eligible for clinical studies and novel treatments available for adult patients at City of Hope, while still benefitting from the patient and family-centered approach of the pediatric program.

Our program offers both outstanding medical treatment and psychosocial support to young cancer patients and their family members. Pediatric oncologists, hematologists, surgeons, radiation oncologists, pathologists and other specialists work in concert to develop a targeted, effective treatment plan.  At the same time, professionals in psychology; social work; child life; recreational, occupational and physical therapy; music therapy; and school reintegration provide individual attention and group activities for patients and their families.

Meet the members of City of Hope’s pediatric leukemia and lymphoma team:
 
The majority of children diagnosed with leukemia or lymphoma are cured; however, there can be long-term side effects. Our Center for Cancer Survivorship clinic is specially designed to meet the follow-up needs of childhood cancer survivors, who are evaluated annually by a team of health care professionals with expertise in survivorship issues.
 
Your child may have the opportunity to participate in a research study or clinical trial through our participation in the Children’s Oncology Group (COG) and our designation as one of only 41 National Cancer Institute (NCI) Comprehensive Cancer Centers in the U.S. More information about our pediatric cancer research, including ongoing clinical trials, is available on City of Hope’s Clinical Trials Online website.
 
Patient Care Overview

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Faces of Cancer

Meet City of Hope patients and their families.
 
 
Clinics/Treatments/Services
As a Comprehensive Cancer Center – the highest designation given by the National Cancer Institute – we are widely regarded as a leader in cancer prevention and treatment.

Cancer Expertise Matters


NEWS & UPDATES
  • It was 2009 when a City of Hope patient in her 40s learned that the cancer she had been fighting for several years had metastasized to her lungs. Her medical team ran genetic tests on the tumor, but none of the drug therapies available at the time targeted the known mutations in the tumor cells. […]
  • Acute myeloid leukemia (AML) is characterized by a rapidly-developing cancer in the myeloid line of blood cells, which is responsible for producing red blood cells, platelets and several types of white blood cells called granulocytes. Because AML grows rapidly, it can quickly crowd out normal blood cells, leadi...
  • Rachel Divine is a yoga therapist and patient leader for the Sheri & Les Biller Patient and Family Resource Center. She’s also a former City of Hope patient. When someone you know has cancer, even the word “cancer” can make you feel nervous, sleepless, depressed or more. But, as a yoga teacher for 15 ...
  •   Diagnosed with type 1 diabetes when she was 9 years old, Gina Marchini accepted the fact that she would need insulin the rest of her life. Every day, she injected herself with the lifesaving hormone. She also carefully controlled her diet and monitored the rise and fall of her blood glucose with military...
  • The defeat of cancer will require a team effort. Nowhere is this more necessary (or apparent) than in efforts to combat two of the most deadly forms of the disease  – pancreatic cancer and triple-negative breast cancer. It’s the approach City of Hope is taking with its newly launched multidisciplinary teams, br...
  • It’s a reasonable question: Why is the National Cancer Institute funding a study on preventing heart failure? The answer is reasonable as well: Rates of heart failure are drastically high among childhood cancer survivors — 15 times higher than among people the same age who were never treated for cancer. T...
  • Many teenagers take a break from academics during the summer, but not the eight high school students enrolled in the California Institute for Regenerative Medicine (CIRM) Creativity Awards program at City of Hope. They took the opportunity to obtain as much hands-on research experience as possible, learning fro...
  • About one in eight women will develop breast cancer at some point in her life. In fact, breast cancer is the most common cancer in American women, behind skin cancer. Although women can’t change some risk factors, such as genetics and the natural aging process, there are certain things they can do to lower thei...
  • As genetic testing becomes more sophisticated, doctors and their patients are finding that such tests can lead to the discovery of previously unknown cancer risks. In his practice at City of Hope, Thomas Slavin, M.D., an assistant clinical professor in the Division of Clinical Cancer Genetics, sees the full spe...
  • And the winners are … everyone in the San Gabriel Valley. The recipients of City of Hope’s first-ever Healthy Living grants have been announced, and the future is looking healthier already. In selecting San Gabriel Valley organizations to receive the grants, City of Hope’s Community Benefits Advisory Council ch...
  • Barry Leshowitz is a former City of Hope patient and a family advisor for the Sheri & Les Biller Patient and Family Resource Center. It’s been almost seven years since I checked into a local hospital in Phoenix for a hip replacement, only to be informed by the surgeon that he had canceled the surgery....
  • When it comes to science, the best graduate schools don’t just train scientists, they prepare their students for a lifetime of learning, accomplishment and positive impact on society. At City of Hope, the Irell & Manella Graduate School of Biological Sciences goes one step further – by preparing students to...
  • Cancer affects not just the cancer patient, but everyone around him or her, even after treatment is complete. The challenges can include the fear of cancer recurrence, coping with cancer’s economic impact and the struggle to achieve work-life balance post-treatment. Family members and loved ones of cancer patie...
  •   Bladder cancer facts: Bladder cancer is a disease in which malignant (cancer) cells form in the tissues of the bladder. 2015 estimates: 74,000 new cases of bladder cancer diagnosed 16,000 deaths from bladder cancer (about 11,510 in men and 4,490 in women) Risk factors for bladder cancer: Smoking: Smokers...
  • Women with ovarian cancer have questions about the most promising treatment options, revolutionary research avenues, survivorship and, of course, the potential impact on their personal lives. Now, together in one place, are experts who can provide answers. On Saturday, Sept. 12, the 2015 Ovarian Cancer Survivor...