A National Cancer Institute-designated Comprehensive Cancer Center

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Leukemia and Lymphoma Programs

At City of Hope, our team of pediatric experts provides comprehensive care for children with leukemia and lymphoma. Leukemia is a cancer of the blood and the most common cancer in children, accounting for approximately 40 percent of all cancer diagnoses in children. Lymphomas are cancers that develop in the body’s lymphatic system and are the third most common pediatric cancer, after leukemia and brain tumors. Our program treats patients with a range of leukemias and lymphomas, including:

Leukemias
 
  • Acute lymphoblastic leukemia (ALL)
  • Acute myeloid leukemia (AML)
  • Chronic myelogenous leukemia (CML)
     
Lymphomas
 
  • Hodgkin lymphoma
  • Non-Hodgkin lymphoma
    • Anaplastic large-cell lymphoma (ALCL)
    • B-cell lymphoma (Burkitt and Burkitt-like lymphoma)
    • Diffuse large B-cell lymphoma (DLBC)
    • Lymphoblastic lymphoma
    • T-cell lymphoma
    • MK-cell lymphoma
       
We treat newly diagnosed patients, as well as patients referred to us from other centers who come to City of Hope to continue their treatment, manage complications of treatment or develop new treatment strategies for cancers not responding to treatment, or for situations in which they have experienced a relapse. For children who fail to respond to treatment or experience a relapse, City of Hope has a renowned program in stem cell transplantation, as well as ongoing studies into novel therapies for relapsed/refractory leukemia.
 
Each type of childhood cancer is treated differently, based on what has been found to be most effective in destroying the particular type of cancer cell. The most common type of cancer treatment for leukemia and lymphoma is chemotherapy. In some cases, radiation therapy and/or stem cell transplant may be recommended. Immunotherapy, or treatment that uses certain parts of the immune system to fight cancer, may be used as well.

A unique benefit of being treated at City of Hope is that we treat young children, adolescents and young adults, ensuring a continuum of care through the years for this special group of patients. Adolescents and young adults may be eligible for clinical studies and novel treatments available for adult patients at City of Hope, while still benefitting from the patient and family-centered approach of the pediatric program.

Our program offers both outstanding medical treatment and psychosocial support to young cancer patients and their family members. Pediatric oncologists, hematologists, surgeons, radiation oncologists, pathologists and other specialists work in concert to develop a targeted, effective treatment plan.  At the same time, professionals in psychology; social work; child life; recreational, occupational and physical therapy; music therapy; and school reintegration provide individual attention and group activities for patients and their families.

Meet the members of City of Hope’s pediatric leukemia and lymphoma team:
 
The majority of children diagnosed with leukemia or lymphoma are cured; however, there can be long-term side effects. Our Center for Cancer Survivorship clinic is specially designed to meet the follow-up needs of childhood cancer survivors, who are evaluated annually by a team of health care professionals with expertise in survivorship issues.
 
Your child may have the opportunity to participate in a research study or clinical trial through our participation in the Children’s Oncology Group (COG) and our designation as one of only 41 National Cancer Institute (NCI) Comprehensive Cancer Centers in the U.S. More information about our pediatric cancer research, including ongoing clinical trials, is available on City of Hope’s Clinical Trials Online website.
 

Leukemia and Lymphoma

Leukemia and Lymphoma Programs

At City of Hope, our team of pediatric experts provides comprehensive care for children with leukemia and lymphoma. Leukemia is a cancer of the blood and the most common cancer in children, accounting for approximately 40 percent of all cancer diagnoses in children. Lymphomas are cancers that develop in the body’s lymphatic system and are the third most common pediatric cancer, after leukemia and brain tumors. Our program treats patients with a range of leukemias and lymphomas, including:

Leukemias
 
  • Acute lymphoblastic leukemia (ALL)
  • Acute myeloid leukemia (AML)
  • Chronic myelogenous leukemia (CML)
     
Lymphomas
 
  • Hodgkin lymphoma
  • Non-Hodgkin lymphoma
    • Anaplastic large-cell lymphoma (ALCL)
    • B-cell lymphoma (Burkitt and Burkitt-like lymphoma)
    • Diffuse large B-cell lymphoma (DLBC)
    • Lymphoblastic lymphoma
    • T-cell lymphoma
    • MK-cell lymphoma
       
We treat newly diagnosed patients, as well as patients referred to us from other centers who come to City of Hope to continue their treatment, manage complications of treatment or develop new treatment strategies for cancers not responding to treatment, or for situations in which they have experienced a relapse. For children who fail to respond to treatment or experience a relapse, City of Hope has a renowned program in stem cell transplantation, as well as ongoing studies into novel therapies for relapsed/refractory leukemia.
 
Each type of childhood cancer is treated differently, based on what has been found to be most effective in destroying the particular type of cancer cell. The most common type of cancer treatment for leukemia and lymphoma is chemotherapy. In some cases, radiation therapy and/or stem cell transplant may be recommended. Immunotherapy, or treatment that uses certain parts of the immune system to fight cancer, may be used as well.

A unique benefit of being treated at City of Hope is that we treat young children, adolescents and young adults, ensuring a continuum of care through the years for this special group of patients. Adolescents and young adults may be eligible for clinical studies and novel treatments available for adult patients at City of Hope, while still benefitting from the patient and family-centered approach of the pediatric program.

Our program offers both outstanding medical treatment and psychosocial support to young cancer patients and their family members. Pediatric oncologists, hematologists, surgeons, radiation oncologists, pathologists and other specialists work in concert to develop a targeted, effective treatment plan.  At the same time, professionals in psychology; social work; child life; recreational, occupational and physical therapy; music therapy; and school reintegration provide individual attention and group activities for patients and their families.

Meet the members of City of Hope’s pediatric leukemia and lymphoma team:
 
The majority of children diagnosed with leukemia or lymphoma are cured; however, there can be long-term side effects. Our Center for Cancer Survivorship clinic is specially designed to meet the follow-up needs of childhood cancer survivors, who are evaluated annually by a team of health care professionals with expertise in survivorship issues.
 
Your child may have the opportunity to participate in a research study or clinical trial through our participation in the Children’s Oncology Group (COG) and our designation as one of only 41 National Cancer Institute (NCI) Comprehensive Cancer Centers in the U.S. More information about our pediatric cancer research, including ongoing clinical trials, is available on City of Hope’s Clinical Trials Online website.
 
Patient Care Overview

City of Hope Locations

Patient Stories and Videos

Meet City of Hope patients and their families.
 
 
Clinics/Treatments/Services
As a Comprehensive Cancer Center – the highest designation given by the National Cancer Institute – we are widely regarded as a leader in cancer prevention and treatment.

Cancer Expertise Matters


NEWS & UPDATES
  • Equipping the immune system to fight cancer – a disease that thrives on mutations and circumventing the body’s natural defenses – is within reach. In fact, City of Hope researchers are testing one approach in clinical trials now. Scientists take a number of steps to turn cancer patients’ T cells – white b...
  • As treatments for lung cancer become more targeted and effective, the need for better technology to detect lung cancer mutations becomes increasingly important. A new clinical study at City of Hope is examining the feasibility of using blood and urine tests to detect lung cancer mutations, potentially allowing ...
  • When it comes to breast cancer risk, insulin levels may matter more than weight, new research has found. The study from Imperial College London School of Public Health, published in the journal Cancer Research, indicates that metabolic health – not a person’s weight or body mass index – increases breast cancer ...
  • No one ever plans to have cancer – and there’s never a good time. For Homa Sadat, her cancer came at a particularly bad time: just one year after losing her father to the pancreatic cancer he had battled for two years. She was working a grueling schedule managing three commercial office buildings. She’d just [&...
  • Patients at City of Hope – most of whom are fighting cancer – rely on more than 37,000 units of blood and platelets each year for their treatment and survival. Every one of those units comes from family, friends or someone who traded an hour or so of their time and a pint of their […]
  • Surgery is vital in the treatment of cancer – it’s used to help diagnose, treat and even prevent the disease – so a new colorectal cancer study linking a decrease in surgeries for advanced cancer to increased survival rates may raise more questions than it answers for some patients. The surgery-and-surviv...
  • Age is the single greatest risk factor overall for cancer; our chances of developing the disease rise steeply after age 50. For geriatric oncology nurse Peggy Burhenn, the meaning is clear: Cancer is primarily a geriatric condition. That’s why she is forging inroads in the care of older adults with cancer. Burh...
  • One of American’s great sportscasters, Stuart Scott, passed away from recurrent cancer of the appendix at the young age of 49. His cancer was diagnosed when he was only 40 years old. It was found during an operation for appendicitis. His courageous fight against this disease began in 2007, resumed again with an...
  • When Homa Sadat found a lump in her breast at age 27, her gynecologist told her what many doctors say to young women: You’re too young to have breast cancer. With the lump dismissed as a harmless cyst, she didn’t think about it again until she was at a restaurant six months later and felt […]
  • What most people call a “bone marrow transplant” is not actually a transplant of bone marrow; it is instead the transplantation of what’s known as hematopoietic stem cells. Such cells are often taken from bone marrow, but not always. Hematopoietic stem cells are simply immature cells that can ...
  • Doctors have long known that women with a precancerous condition called atypical hyperplasia have an elevated risk of breast cancer. Now a new study has found that the risk is more serious than previously thought. Hyperplasia itself is an overgrowth of cells; atypical hyperplasia is an overgrowth in a distorted...
  • Don’t kid yourself. Just because it’s mid-January doesn’t mean it’s too late to make resolutions for a happier, and healthier, 2015. Just consider them resolutions that are more mature than those giddy, sometimes self-deluded, Jan. 1 resolutions. To that end, we share some advice from Cary A. Presant, M.D., an ...
  • Sales and marketing executive Jim Murphy first came to City of Hope in 2002 to donate blood for a friend who was being treated for esophageal cancer. The disease is serious. Although esophageal cancer accounts for only about 1 percent of cancer diagnoses in the U.S., only about 20 percent of patients survive at...
  • Aaron Bomar and his family were celebrating his daughter’s 33rd birthday in September 2014 when he received alarming news: According to an X-ray taken earlier that day at an urgent care facility, he had a node on his aorta and was in danger of an aneurysm. Bomar held hands with his wife and daughter and s...
  • Explaining a prostate cancer diagnosis to a young child can be difficult — especially when the cancer is incurable. But conveying the need for prostate cancer research, as it turns out, is easily done. And that leads to action. Earlier this year, Gerald Rustad, 71, who is living with a very aggressive form of m...