Contact Information
Mei Kong, Ph.D.
  • Assistant Professor, Cancer Biology

Languages Spoken
  • English
  • Mandarin (Chinese)

Professional Experience

  • 2010 - present, Faculty Member, City of Hope's Irell & Manell Graduate School of Biological Cancer, Duarte, CA
  • 2009 - 2010, Research Associate, Department of Cancer Biology, University of Pennsylvania, Pennsylvania, PA

Education

Education/Training
  • 2003 - 2009, Abramson Family Cancer Research Institute, University of Pennsylvania, Pennsylvania, PA, Cancer Biology, Postdoctoral Fellow
  • 2003, McGill University, Montreal, Canada, Experimental Medicine, Ph.D.

Honors/Awards

Awards
  • 2013, V Scholar, the V Foundation for Cancer Research
  • 2011, Pew Scholar in the Biomedical Sciences, Pew Charitable Trusts
  • 2011, Stand Up To Cancer Innovative Research Grant recipient
  • 2011, Kimmel Scholar Award, Sidney Kimmel Foundation for Cancer Research
  • 2011, Marni Levine Memorial Research Career Development Award, Stop Cancer Foundation
  • 2007, Career Development Award (Special Fellow), The Leukemia and Lymphoma Society
  • 2006, AACR-Pennsylvania Department of Health Fellowship in Cancer Research, American Association for Cancer Research
  • 2004, Two-year postdoctoral fellowship, Lymphoma Research Foundation

Honors
  • 2003, Dean’s Honor List, McGill University
 

Memberships

  • 2010 - present, Active member of the American Association for Cancer Research (AACR) and AACR-Women in Cancer Research (WICR)

Publications

Selected Publications
 
  • Reid MA, Kong M. Dealing with hunger: Metabolic stress response in tumors. J Carcinog. 30: 12-17 (2013)
  • Reid MA, Kong M.  Adaptation to metabolic stress: insights into a paradoxical Q.  Cell Cycle 12:1807-1808 (2013)
  • Reid MA, Wang WI, Rosales KR, Welliver MX, Pan M, and Kong M. The B55α subunit of PP2A drives a p53-dependent metabolic adaptation to glutamine deprivation. Molecular Cell 50: 200-211 (2013)
  • Jiang L, Stanevich V, Satyshur KA, Kong M, Watkins GR, Wadzinski BE, Sengupta R, Xing Y.
  • Structural basis of protein phosphatase 2A stable latency. Nature Communication Apr 16 (2013)
  • Lin TC, Chen YR, Kensicki E, Li AY, Kong M, Li Y, Mohney RP, Shen HM, Stiles B, Mizushima N, Lin LI, Ann DK. Autophagy: resetting glutamine-dependent metabolism and oxygen consumption. Autophagy 10:1477-93 (2012)
  • Kong M *, Ditsworth D *, Lindsten T, and Thompson CB. α4 is an essential regulator of PP2A phosphatase activity. Molecular Cell 36:51-60 (2009) (* equal contribution)
  • Gruber J, Yong J, Zatechka DS, Sabin L, Zhang Z, Lum JJ, Kong M, Zong WX, Lau CK, Cherry S, Ihle J,  Dreyfuss G, and Thompson CB. Ars2 links the nuclear cap binding complex to RNA interference and cell proliferation. Cell  138:328-39, (2009)
  • Kong M, Bui TV,  Ditsworth D, Gruber JJ,  Goncharov D,  Krymskaya VP,  Lindsten T,  and Thompson CB.  The PP2A-associated protein α4 plays a critical role in the regulation of cell spreading and migration. J. Biol. Chem. 282:29712-20, (2007)
  • Lum JJ, Bauer DE, Kong M, Harris MH, Li C, Lindsten T, Thompson CB. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 120:237-48 (2005)
  • Kong M, Fox CJ, Mu J, Solt L, Xu A, Cinalli RM, Birnbaum MJ, Lindsten T, Thompson CB. The PP2A-associated protein α4 is an essential inhibitor of apoptosis. Science  306:695-8 (2004)
  • Kong M, Mounier C, Dumas V, Posner BI. Gab2 tyrosine phosphorylation by a pleckstrin homology domain-independent mechanism: role in epidermal growth factor-induced mitogenesis. Mol. Endocrinol. 17:935-44 (2003).
  • Kong M, Mounier C, Balbis A, Baquiran G, Posner BI. Epidermal growth factor-induced DNA synthesis. Key role for Src phosphorylation of the docking protein Gab2. J. Biol. Chem. 278:5837-44 (2003).
  • Kong M, Mounier C, Wu J, Posner BI. Epidermal growth factor-induced phosphatidylinositol 3-kinase activation and DNA synthesis: Identification of Grb2-associated binder 2 as the major mediator in rat hepatocytes. J. Biol. Chem. 275:36035-42 (2000).
  • Lavoie L, Band CJ, Kong M, Bergeron JJ, Posner BI. Regulation of glycogen synthase in rat hepatocytes: Evidence for multiple signaling pathways. J. Biol. Chem. 274:28279-85 (1999).
 

Research

For more information on Dr. Kong's research, please click here.