A National Cancer Institute-designated Comprehensive Cancer Center

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Why Choose City of Hope?

Institutional distinctions
 
  • City of Hope is one of 41 comprehensive cancer centers, the highest designation bestowed by the National Cancer Institute for excellence in cancer treatment, research, prevention and education.
  • City of Hope is ranked as one of “America’s Best Hospitals” in cancer by U.S.News & World Report.
  • City of Hope is a founding member of the National Comprehensive Cancer Network (NCCN), meaning our research and treatment protocols advance care throughout the nation.
  • In the 2014 fiscal year, City of Hope was awarded more than $72.9 million in research grants and received approximately $249.8 million in revenues from patented technologies.
  • City of Hope has earned its sixth consecutive Press Ganey Guardian of Excellence Award.
  • City of Hope is part of ORIEN (Oncology Research Information Exchange Network), the world's largest cancer research collaboration devoted to precision medicine.
  • We were recently awarded the highest level of accreditation by the American College of Surgeons Commision on Cancer for our exceptional level of cancer care, "Three-Year with Commendation." This is the second consecutive time that we have received this prestigious rating.
  • City of Hope has earned the highest rating - 4 stars - from the nation’s leading charity watchdog, Charity Navigator. The four-star rating reflect City of Hope's sound fiscal management, financial stability and growth.
 
A record of innovation
 
  • Numerous breakthrough cancer drugs, including Herceptin, Rituxan and Avastin, are based on technology pioneered by City of Hope and are saving lives worldwide.
  • Millions of people with diabetes benefit from synthetic human insulin, developed through research conducted at City of Hope.
  • City of Hope was a pioneer in bone marrow and stem cell transplants - and our program is now one of the largest, most successful programs of its kind in the world. We’ve performed more than 12,000 bone marrow and stem cell transplants, with survival rates that are unparalleled.
  • Surgeons at City of Hope have performed more than 10,000 robotic procedures for prostate, kidney, colon, liver, bladder, gynecologic, oral and other cancers.
 
Speed, efficiency and collaboration
 
  • Our research facilities set us apart. We have not one, but three, manufacturing facilities on campus that manufacture both biologic and chemical compounds to good manufacturing practice (GMP) standards. This infrastructure helps us quickly turn breakthrough discoveries into lifesaving therapies.
  • City of Hope has more than 300 patents and currently have 30 investigational new drug applications. These numbers are exceptionally large for an organization of City of Hope’s size, reflecting our commitment to innovation and speeding treatments to patients.
  • A uniquely collaborative environment makes it easy for laboratory and clinical researchers at City of Hope to more quickly translate breakthroughs into therapies.
  • Beckman Research Institute of City of Hope was the first of five Beckman Institutes in the United States, which together have fueled scientific advances for more than a generation.
 
Science that is saving lives
 
  • City of Hope researchers are investigating ways to harness the body’s natural defenses to fight cancer, an approach known as “immunotherapy.”
    • One approach strikes a dual blow - shutting off a gene that promotes cancer while stimulating the immune system to act - in an effort to fight lymphoma and melanoma as well as brain, ovarian and prostate cancers.
    • Other studies are focused on engaging every stage of the immune response to defeat breast cancer.
  • City of Hope scientists studying “superfoods” have found that an extract of white button mushrooms can help block hormones that cause breast cancer and prostate cancer to grow and spread.  They’re also researching the anti-cancer properties of other “superfoods” such as blueberries, pomegranates and grape seed extract.
  • Because life after cancer treatment can present both physical and emotional challenges, City of Hope creates a bridge between treatment and ongoing support. The Center for Cancer Survivorship provides specialized follow-up care and education for survivors of pediatric, prostate and breast cancers. The resulting research is helping physicians understand the long-term effects of cancer and
    its treatment - influencing how care is delivered today at City of Hope and beyond.

Beyond the study of cancer
 
  • By investigating the molecular mechanisms of diabetes complications, City of Hope scientists are helping develop new treatments for them. They also are studying the use of blood stem cell transplantation to reboot the immune system in type 1 diabetes, an autoimmune disease.
  • City of Hope is a national leader in islet cell transplantation, which has the potential to reverse type 1 diabetes. In addition, we provide islet cells for research at other institutions throughout the U.S.
  • Researchers here are investigating new connections between diabetes and cancer, such as inflammation. What we discover about one disease could hold cures to advances against the other.
     
Toward a lasting cure for HIV/AIDS
 
  • City of Hope scientists pioneered the application of blood stem cell transplants to treat patients with HIV and AIDS-related lymphoma. Our researchers used a new form of gene therapy to achieve the first long-term persistence of anti-HIV genes in patients with AIDS-related lymphoma. This treatment ultimately may cure not only lymphoma, but also HIV/AIDS, and our researchers are now expanding their studies with a new clinical trial.
 
The philanthropic support that makes it all possible
 
  • City of Hope is powered by philanthropy. It was launched in the firm belief that all of us have the potential to change the fate of individuals even as we improve medical care overall.
  • “There is no profit in curing the body if, in the process, we destroy the soul.” Those words were spoken by Samuel H. Golter, one of our early leaders, and they remain the credo that guides City of Hope’s approach to patient care. We are committed to treating the whole person not only by providing the best medical care possible, but also by providing that care in an atmosphere of kindness and compassion.
  • Year after year, foundations, philanthropists, business leaders, global corporations, small businesses and hundreds of thousands of other caring individuals of all ages contribute generously to support the lifesaving work of City of Hope.
  • Many professional sports organizations have supported City of Hope, including the Los Angeles Dodgers, the Los Angeles Kings, Major League Soccer’s Chivas USA and the National Football League. City of Hope has been named the official charity of the historic Northern Trust Open, and through 2025, will partner with the Northern Trust and PGA TOUR to raise funds and awareness for cancer and diabetes research.

Why Choose City of Hope?

Why Choose City of Hope?

Institutional distinctions
 
  • City of Hope is one of 41 comprehensive cancer centers, the highest designation bestowed by the National Cancer Institute for excellence in cancer treatment, research, prevention and education.
  • City of Hope is ranked as one of “America’s Best Hospitals” in cancer by U.S.News & World Report.
  • City of Hope is a founding member of the National Comprehensive Cancer Network (NCCN), meaning our research and treatment protocols advance care throughout the nation.
  • In the 2014 fiscal year, City of Hope was awarded more than $72.9 million in research grants and received approximately $249.8 million in revenues from patented technologies.
  • City of Hope has earned its sixth consecutive Press Ganey Guardian of Excellence Award.
  • City of Hope is part of ORIEN (Oncology Research Information Exchange Network), the world's largest cancer research collaboration devoted to precision medicine.
  • We were recently awarded the highest level of accreditation by the American College of Surgeons Commision on Cancer for our exceptional level of cancer care, "Three-Year with Commendation." This is the second consecutive time that we have received this prestigious rating.
  • City of Hope has earned the highest rating - 4 stars - from the nation’s leading charity watchdog, Charity Navigator. The four-star rating reflect City of Hope's sound fiscal management, financial stability and growth.
 
A record of innovation
 
  • Numerous breakthrough cancer drugs, including Herceptin, Rituxan and Avastin, are based on technology pioneered by City of Hope and are saving lives worldwide.
  • Millions of people with diabetes benefit from synthetic human insulin, developed through research conducted at City of Hope.
  • City of Hope was a pioneer in bone marrow and stem cell transplants - and our program is now one of the largest, most successful programs of its kind in the world. We’ve performed more than 12,000 bone marrow and stem cell transplants, with survival rates that are unparalleled.
  • Surgeons at City of Hope have performed more than 10,000 robotic procedures for prostate, kidney, colon, liver, bladder, gynecologic, oral and other cancers.
 
Speed, efficiency and collaboration
 
  • Our research facilities set us apart. We have not one, but three, manufacturing facilities on campus that manufacture both biologic and chemical compounds to good manufacturing practice (GMP) standards. This infrastructure helps us quickly turn breakthrough discoveries into lifesaving therapies.
  • City of Hope has more than 300 patents and currently have 30 investigational new drug applications. These numbers are exceptionally large for an organization of City of Hope’s size, reflecting our commitment to innovation and speeding treatments to patients.
  • A uniquely collaborative environment makes it easy for laboratory and clinical researchers at City of Hope to more quickly translate breakthroughs into therapies.
  • Beckman Research Institute of City of Hope was the first of five Beckman Institutes in the United States, which together have fueled scientific advances for more than a generation.
 
Science that is saving lives
 
  • City of Hope researchers are investigating ways to harness the body’s natural defenses to fight cancer, an approach known as “immunotherapy.”
    • One approach strikes a dual blow - shutting off a gene that promotes cancer while stimulating the immune system to act - in an effort to fight lymphoma and melanoma as well as brain, ovarian and prostate cancers.
    • Other studies are focused on engaging every stage of the immune response to defeat breast cancer.
  • City of Hope scientists studying “superfoods” have found that an extract of white button mushrooms can help block hormones that cause breast cancer and prostate cancer to grow and spread.  They’re also researching the anti-cancer properties of other “superfoods” such as blueberries, pomegranates and grape seed extract.
  • Because life after cancer treatment can present both physical and emotional challenges, City of Hope creates a bridge between treatment and ongoing support. The Center for Cancer Survivorship provides specialized follow-up care and education for survivors of pediatric, prostate and breast cancers. The resulting research is helping physicians understand the long-term effects of cancer and
    its treatment - influencing how care is delivered today at City of Hope and beyond.

Beyond the study of cancer
 
  • By investigating the molecular mechanisms of diabetes complications, City of Hope scientists are helping develop new treatments for them. They also are studying the use of blood stem cell transplantation to reboot the immune system in type 1 diabetes, an autoimmune disease.
  • City of Hope is a national leader in islet cell transplantation, which has the potential to reverse type 1 diabetes. In addition, we provide islet cells for research at other institutions throughout the U.S.
  • Researchers here are investigating new connections between diabetes and cancer, such as inflammation. What we discover about one disease could hold cures to advances against the other.
     
Toward a lasting cure for HIV/AIDS
 
  • City of Hope scientists pioneered the application of blood stem cell transplants to treat patients with HIV and AIDS-related lymphoma. Our researchers used a new form of gene therapy to achieve the first long-term persistence of anti-HIV genes in patients with AIDS-related lymphoma. This treatment ultimately may cure not only lymphoma, but also HIV/AIDS, and our researchers are now expanding their studies with a new clinical trial.
 
The philanthropic support that makes it all possible
 
  • City of Hope is powered by philanthropy. It was launched in the firm belief that all of us have the potential to change the fate of individuals even as we improve medical care overall.
  • “There is no profit in curing the body if, in the process, we destroy the soul.” Those words were spoken by Samuel H. Golter, one of our early leaders, and they remain the credo that guides City of Hope’s approach to patient care. We are committed to treating the whole person not only by providing the best medical care possible, but also by providing that care in an atmosphere of kindness and compassion.
  • Year after year, foundations, philanthropists, business leaders, global corporations, small businesses and hundreds of thousands of other caring individuals of all ages contribute generously to support the lifesaving work of City of Hope.
  • Many professional sports organizations have supported City of Hope, including the Los Angeles Dodgers, the Los Angeles Kings, Major League Soccer’s Chivas USA and the National Football League. City of Hope has been named the official charity of the historic Northern Trust Open, and through 2025, will partner with the Northern Trust and PGA TOUR to raise funds and awareness for cancer and diabetes research.
Welcome to City of Hope
City of Hope is a new model of cancer center, focused on rapidly transforming scientific discoveries into better treatments and better prevention strategies for cancer, diabetes, HIV/AIDS and other life-threatening diseases.

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Learn about the talented individuals who are leading City of Hope towards the next horizon of treatments and cures for life-threatening diseases.

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City of Hope's institutional distinctions, breakthrough innovations and collaborations.
 


NEWS & UPDATES
  • It was 2009 when a City of Hope patient in her 40s learned that the cancer she had been fighting for several years had metastasized to her lungs. Her medical team ran genetic tests on the tumor, but none of the drug therapies available at the time targeted the known mutations in the tumor cells. […]
  • Acute myeloid leukemia (AML) is characterized by a rapidly-developing cancer in the myeloid line of blood cells, which is responsible for producing red blood cells, platelets and several types of white blood cells called granulocytes. Because AML grows rapidly, it can quickly crowd out normal blood cells, leadi...
  • Rachel Divine is a yoga therapist and patient leader for the Sheri & Les Biller Patient and Family Resource Center. She’s also a former City of Hope patient. When someone you know has cancer, even the word “cancer” can make you feel nervous, sleepless, depressed or more. But, as a yoga teacher for 15 ...
  •   Diagnosed with type 1 diabetes when she was 9 years old, Gina Marchini accepted the fact that she would need insulin the rest of her life. Every day, she injected herself with the lifesaving hormone. She also carefully controlled her diet and monitored the rise and fall of her blood glucose with military...
  • The defeat of cancer will require a team effort. Nowhere is this more necessary (or apparent) than in efforts to combat two of the most deadly forms of the disease  – pancreatic cancer and triple-negative breast cancer. It’s the approach City of Hope is taking with its newly launched multidisciplinary teams, br...
  • It’s a reasonable question: Why is the National Cancer Institute funding a study on preventing heart failure? The answer is reasonable as well: Rates of heart failure are drastically high among childhood cancer survivors — 15 times higher than among people the same age who were never treated for cancer. T...
  • Many teenagers take a break from academics during the summer, but not the eight high school students enrolled in the California Institute for Regenerative Medicine (CIRM) Creativity Awards program at City of Hope. They took the opportunity to obtain as much hands-on research experience as possible, learning fro...
  • About one in eight women will develop breast cancer at some point in her life. In fact, breast cancer is the most common cancer in American women, behind skin cancer. Although women can’t change some risk factors, such as genetics and the natural aging process, there are certain things they can do to lower thei...
  • As genetic testing becomes more sophisticated, doctors and their patients are finding that such tests can lead to the discovery of previously unknown cancer risks. In his practice at City of Hope, Thomas Slavin, M.D., an assistant clinical professor in the Division of Clinical Cancer Genetics, sees the full spe...
  • And the winners are … everyone in the San Gabriel Valley. The recipients of City of Hope’s first-ever Healthy Living grants have been announced, and the future is looking healthier already. In selecting San Gabriel Valley organizations to receive the grants, City of Hope’s Community Benefits Advisory Council ch...
  • Barry Leshowitz is a former City of Hope patient and a family advisor for the Sheri & Les Biller Patient and Family Resource Center. It’s been almost seven years since I checked into a local hospital in Phoenix for a hip replacement, only to be informed by the surgeon that he had canceled the surgery....
  • When it comes to science, the best graduate schools don’t just train scientists, they prepare their students for a lifetime of learning, accomplishment and positive impact on society. At City of Hope, the Irell & Manella Graduate School of Biological Sciences goes one step further – by preparing students to...
  • Cancer affects not just the cancer patient, but everyone around him or her, even after treatment is complete. The challenges can include the fear of cancer recurrence, coping with cancer’s economic impact and the struggle to achieve work-life balance post-treatment. Family members and loved ones of cancer patie...
  •   Bladder cancer facts: Bladder cancer is a disease in which malignant (cancer) cells form in the tissues of the bladder. 2015 estimates: 74,000 new cases of bladder cancer diagnosed 16,000 deaths from bladder cancer (about 11,510 in men and 4,490 in women) Risk factors for bladder cancer: Smoking: Smokers...
  • Women with ovarian cancer have questions about the most promising treatment options, revolutionary research avenues, survivorship and, of course, the potential impact on their personal lives. Now, together in one place, are experts who can provide answers. On Saturday, Sept. 12, the 2015 Ovarian Cancer Survivor...