A National Cancer Institute-designated Comprehensive Cancer Center

Make an appointment: 800-826-HOPE
Why Choose City of Hope? Bookmark and Share

Why Choose City of Hope?

Institutional distinctions
 
  • City of Hope is one of 41 comprehensive cancer centers, the highest designation bestowed by the National Cancer Institute for excellence in cancer treatment, research, prevention and education.
  • City of Hope is ranked as one of “America’s Best Hospitals” in cancer by U.S.News & World Report.
  • City of Hope maintains the No. 1 hematology, prostate cancer and breast cancer programs in California, based on the number of patients treated.
  • City of Hope was awarded more than $79.7 million in research grants during 2012 and received $224.6 million in revenues from patented technologies in the 2012 fiscal year.
  • City of Hope is a pioneer of patient-centered care and remains committed to its tradition of exceptional compassionate care for patients and families. Each day, we live out our credo: “There is no profit in curing the body if, in the process, we destroy the soul.”
  • City of Hope has earned the highest rating — 4 stars — from the nation’s leading charity watchdog, Charity Navigator, in eight consecutive evaluations. That puts us among the top 2 percent of the charities rated by the organization.
  • City of Hope is supported by a unique nationwide network of more than 20 industry groups and hundreds of fundraising chapters, all of which serve as valuable partners in advancing our mission.
 
A record of innovation
 
  • Numerous breakthrough cancer drugs, including Herceptin, Rituxan and Avastin, are based on technology pioneered by City of Hope and are saving lives worldwide.
  • Millions of people with diabetes benefit from synthetic human insulin, developed through research conducted at City of Hope.
  • A pioneer in bone marrow transplantation, City of Hope has performed more than 12,000 bone marrow and stem cell transplants and operates one of the largest, most successful programs of its kind in the world. For eight years in a row, our bone marrow transplant program has performed above expectations in one-year patient survival. We are the only program in the country to achieve these outcomes for eight straight years.
  • City of Hope was one of the first cancer centers in the country to adopt robotic prostate surgery, in 2003. Since then, surgeons at City of Hope have performed more than 6,000 robotic procedures for prostate cancer.
 
Speed, efficiency and collaboration
 
  • City of Hope has not one but three on-site manufacturing facilities that enable investigators to manufacture promising new therapies without the high cost and delays encountered by other research centers. These capabilities save years of development time and ensure that we can rapidly and efficiently translate discoveries into beneficial treatments.
  • City of Hope has more than 200 patents and currently have 29 investigational new drug applications. These numbers are exceptionally large for an organization of City of Hope’s size, reflecting our commitment to innovation and speeding treatments to patients.
  • A uniquely collaborative environment makes it easy for laboratory and clinical researchers at City of Hope to more quickly translate breakthroughs into therapies.
  • City of Hope’s scientists collaborate with colleagues around the world. We participate in more than 300 projects with institutions throughout the nation and around the world. No matter where you live, there is likely collaboration between City of Hope and a center near you.
 
Transforming the future of cancer care
 
  • City of Hope researchers are investigating ways to harness the body’s natural defenses to fight cancer, an approach known as “immunotherapy.” One approach aims to harvest from patients the immune system’s T cells and reprogram them to defeat lymphoma and brain cancer. Another approach strikes a dual blow — shutting off a gene that promotes cancer while stimulating the immune system to action — in an effort to fight lymphoma and melanoma as well as brain, ovarian and prostate cancers. Other studies are focused on engaging every stage of the immune response to fight off breast cancer.
  • In 2010, we were the first institution in the world to use neural stem cells as a targeted delivery mechanism to treat patients with glioma, an aggressive type of brain tumor.
  • We have 29 novel therapies in our drug pipeline.
  • City of Hope scientists studying “super foods” to look at the anti-cancer properties contained within blueberries, mushrooms, cinnamon, pomegranates and grape seed extract, with the hope that they can be used to help prevent or treat cancer in a more effective way.
  • City of Hope researchers are pursuing a high-tech form of targeted radiation therapy to ease side effects of bone marrow and stem cell transplants. This approach, tested here first, uses total marrow irradiation, or TMI, as a replacement for irradiating a patient’s whole body before transplant. Researchers hope this approach will reduce the impact on healthy tissue while allowing for higher doses of therapeutic radiation.
  • Because life after cancer treatment can present both physical and emotional challenges, City of Hope creates a bridge between treatment and ongoing support. The Center for Cancer Survivorship provides specialized follow-up care and education for survivors of pediatric, prostate and breast cancers. The research that results from this program is helping physicians understand the long-term effects of cancer and its treatment — influencing how care is delivered today.
  • The Sheri & Les Biller Patient and Family Resource Center offers the most integrated array of support services in the country. One team can provide patients with navigation help, counseling, support groups and other resources that address their physical, emotional and spiritual needs. The research and tools developed through this approach will help patients everywhere.
 
Breakthroughs against diabetes
 
  • By investigating the molecular mechanisms of diabetes complications, City of Hope scientists are helping develop new treatments for them. They also are studying the use of blood stem cell transplantation to reboot the immune system in type 1 diabetes, an autoimmune disease.
  • City of Hope is a national leader in islet cell transplantation, which has the potential to reverse type 1 diabetes. In addition, we provide islet cells for research at other institutions throughout the U.S.
  • Researchers here are investigating new connections between diabetes and cancer, such as inflammation. What we discover about one disease could hold cures to advances against the other.
     
Toward a lasting cure for HIV/AIDS
 
  • City of Hope scientists pioneered the application of blood stem cell transplants to treat patients with HIV and AIDS-related lymphoma. Our researchers used a new form of gene therapy to achieve the first long-term persistence of anti-HIV genes in patients with AIDS-related lymphoma. This treatment ultimately may cure not only lymphoma, but also HIV/AIDS.
 
The philanthropic support that makes it all possible
 
  • Year after year, foundations, philanthropists, business leaders, global corporations, small businesses and hundreds of thousands of other caring individuals of all ages contribute generously to support the lifesaving work of City of Hope.
  • Celebrities supporting City of Hope through appearances, public service announcements and fundraising include the public faces of our Citizens of Hope awareness campaign: Kiefer Sutherland, Archie Panjabi, Taraji P. Henson, Josie Maran and Selena Gomez.
  • Many professional sports organizations have given their support to City of Hope, including the Los Angeles Dodgers, the Los Angeles Kings and Major League Soccer’s Chivas USA. City of Hope also was the 2009–10 official charity of the NFL on FOX. As the official charity of the Northern Trust Open, City of Hope has joined forces with Northern Trust and the PGA TOUR to bring hope to patients.

Why Choose City of Hope?

Why Choose City of Hope?

Institutional distinctions
 
  • City of Hope is one of 41 comprehensive cancer centers, the highest designation bestowed by the National Cancer Institute for excellence in cancer treatment, research, prevention and education.
  • City of Hope is ranked as one of “America’s Best Hospitals” in cancer by U.S.News & World Report.
  • City of Hope maintains the No. 1 hematology, prostate cancer and breast cancer programs in California, based on the number of patients treated.
  • City of Hope was awarded more than $79.7 million in research grants during 2012 and received $224.6 million in revenues from patented technologies in the 2012 fiscal year.
  • City of Hope is a pioneer of patient-centered care and remains committed to its tradition of exceptional compassionate care for patients and families. Each day, we live out our credo: “There is no profit in curing the body if, in the process, we destroy the soul.”
  • City of Hope has earned the highest rating — 4 stars — from the nation’s leading charity watchdog, Charity Navigator, in eight consecutive evaluations. That puts us among the top 2 percent of the charities rated by the organization.
  • City of Hope is supported by a unique nationwide network of more than 20 industry groups and hundreds of fundraising chapters, all of which serve as valuable partners in advancing our mission.
 
A record of innovation
 
  • Numerous breakthrough cancer drugs, including Herceptin, Rituxan and Avastin, are based on technology pioneered by City of Hope and are saving lives worldwide.
  • Millions of people with diabetes benefit from synthetic human insulin, developed through research conducted at City of Hope.
  • A pioneer in bone marrow transplantation, City of Hope has performed more than 12,000 bone marrow and stem cell transplants and operates one of the largest, most successful programs of its kind in the world. For eight years in a row, our bone marrow transplant program has performed above expectations in one-year patient survival. We are the only program in the country to achieve these outcomes for eight straight years.
  • City of Hope was one of the first cancer centers in the country to adopt robotic prostate surgery, in 2003. Since then, surgeons at City of Hope have performed more than 6,000 robotic procedures for prostate cancer.
 
Speed, efficiency and collaboration
 
  • City of Hope has not one but three on-site manufacturing facilities that enable investigators to manufacture promising new therapies without the high cost and delays encountered by other research centers. These capabilities save years of development time and ensure that we can rapidly and efficiently translate discoveries into beneficial treatments.
  • City of Hope has more than 200 patents and currently have 29 investigational new drug applications. These numbers are exceptionally large for an organization of City of Hope’s size, reflecting our commitment to innovation and speeding treatments to patients.
  • A uniquely collaborative environment makes it easy for laboratory and clinical researchers at City of Hope to more quickly translate breakthroughs into therapies.
  • City of Hope’s scientists collaborate with colleagues around the world. We participate in more than 300 projects with institutions throughout the nation and around the world. No matter where you live, there is likely collaboration between City of Hope and a center near you.
 
Transforming the future of cancer care
 
  • City of Hope researchers are investigating ways to harness the body’s natural defenses to fight cancer, an approach known as “immunotherapy.” One approach aims to harvest from patients the immune system’s T cells and reprogram them to defeat lymphoma and brain cancer. Another approach strikes a dual blow — shutting off a gene that promotes cancer while stimulating the immune system to action — in an effort to fight lymphoma and melanoma as well as brain, ovarian and prostate cancers. Other studies are focused on engaging every stage of the immune response to fight off breast cancer.
  • In 2010, we were the first institution in the world to use neural stem cells as a targeted delivery mechanism to treat patients with glioma, an aggressive type of brain tumor.
  • We have 29 novel therapies in our drug pipeline.
  • City of Hope scientists studying “super foods” to look at the anti-cancer properties contained within blueberries, mushrooms, cinnamon, pomegranates and grape seed extract, with the hope that they can be used to help prevent or treat cancer in a more effective way.
  • City of Hope researchers are pursuing a high-tech form of targeted radiation therapy to ease side effects of bone marrow and stem cell transplants. This approach, tested here first, uses total marrow irradiation, or TMI, as a replacement for irradiating a patient’s whole body before transplant. Researchers hope this approach will reduce the impact on healthy tissue while allowing for higher doses of therapeutic radiation.
  • Because life after cancer treatment can present both physical and emotional challenges, City of Hope creates a bridge between treatment and ongoing support. The Center for Cancer Survivorship provides specialized follow-up care and education for survivors of pediatric, prostate and breast cancers. The research that results from this program is helping physicians understand the long-term effects of cancer and its treatment — influencing how care is delivered today.
  • The Sheri & Les Biller Patient and Family Resource Center offers the most integrated array of support services in the country. One team can provide patients with navigation help, counseling, support groups and other resources that address their physical, emotional and spiritual needs. The research and tools developed through this approach will help patients everywhere.
 
Breakthroughs against diabetes
 
  • By investigating the molecular mechanisms of diabetes complications, City of Hope scientists are helping develop new treatments for them. They also are studying the use of blood stem cell transplantation to reboot the immune system in type 1 diabetes, an autoimmune disease.
  • City of Hope is a national leader in islet cell transplantation, which has the potential to reverse type 1 diabetes. In addition, we provide islet cells for research at other institutions throughout the U.S.
  • Researchers here are investigating new connections between diabetes and cancer, such as inflammation. What we discover about one disease could hold cures to advances against the other.
     
Toward a lasting cure for HIV/AIDS
 
  • City of Hope scientists pioneered the application of blood stem cell transplants to treat patients with HIV and AIDS-related lymphoma. Our researchers used a new form of gene therapy to achieve the first long-term persistence of anti-HIV genes in patients with AIDS-related lymphoma. This treatment ultimately may cure not only lymphoma, but also HIV/AIDS.
 
The philanthropic support that makes it all possible
 
  • Year after year, foundations, philanthropists, business leaders, global corporations, small businesses and hundreds of thousands of other caring individuals of all ages contribute generously to support the lifesaving work of City of Hope.
  • Celebrities supporting City of Hope through appearances, public service announcements and fundraising include the public faces of our Citizens of Hope awareness campaign: Kiefer Sutherland, Archie Panjabi, Taraji P. Henson, Josie Maran and Selena Gomez.
  • Many professional sports organizations have given their support to City of Hope, including the Los Angeles Dodgers, the Los Angeles Kings and Major League Soccer’s Chivas USA. City of Hope also was the 2009–10 official charity of the NFL on FOX. As the official charity of the Northern Trust Open, City of Hope has joined forces with Northern Trust and the PGA TOUR to bring hope to patients.
Welcome to City of Hope
City of Hope is a new model of cancer center, focused on rapidly transforming scientific discoveries into better treatments and better prevention strategies for cancer, diabetes, HIV/AIDS and other life-threatening diseases.

Virtual Tour of City of Hope
City of Hope Locations

Learn about the talented individuals who are leading City of Hope towards the next horizon of treatments and cures for life-threatening diseases.

Learn more about
City of Hope's institutional distinctions, breakthrough innovations and collaborations.
 
NEWS & UPDATES
  • Advances in cancer treatment, built on discoveries made in the laboratory then brought to the bedside, have phenomenally changed the reality of living with a cancer diagnosis. More than any other time in history, people diagnosed with cancer are more likely to survive and to enjoy a high quality of life. Howeve...
  • While health care reform has led to an increase in the number of people signing up for health insurance, many people remain uninsured or are not taking full advantage of the health benefits they now have. Still others are finding that, although their premiums are affordable, they aren’t able to see the do...
  • Kidney cancer rates and thyroid cancer rates in adults have continued to rise year after year. Now a new study has found that incidence rates for these cancers are also increasing in children — particularly in African-American children. The study, published online this month in Pediatrics, examined childhood ca...
  • Thyroid cancer has become one of the fastest-growing cancers in the United States for both men and women. The chance of being diagnosed with the cancer has nearly doubled since 1990. This year an estimated 63,000 people will be diagnosed with thyroid cancer in the United States and nearly 1,900 people will die ...
  • Older teenagers and young adults traditionally face worse outcomes than younger children when diagnosed with brain cancer and other central nervous system tumors. A first-of-its-kind study shows why. A team of researchers from the departments of Population Sciences and Pathology at City of Hope recently examine...
  • Cancer treatment can take a toll on the mouth, even if a patient’s cancer has nothing to do with the head or throat, leading to a dry mouth, or a very sore mouth, and making it difficult to swallow or eat. Here’s some advice from the National Cancer Institute (NCI)  on how to ease cancer-related dis...
  • Radiation oncology is one of the three main specialties involved in the successful treatment of cancer, along with surgical oncology and medical oncology. Experts in this field, known as radiation oncologists, advise patients as to whether radiation therapy will be useful for their cancer – and how it can best ...
  • There’s more to cancer care than simply helping patients survive. There’s more to cancer treatment than simple survival. Constant pain should not be part of conquering cancer,  insists Betty Ferrell, Ph.D., R.N., director of nursing research and education at City of Hope. She wants patients and caregivers...
  • Even its name is daunting. Systemic mastocytosis is a fatal disease of the blood with no known cure. But a new study suggests a bone marrow transplant may be the answer for some patients. While rare, systemic mastocytosis is resistant to treatment with drugs and, when aggressive, can be fatal within four years ...
  • Could what you eat affect the health of your chromosomes? The short answer is, “Yes.” Researchers led by Dustin Schones, Ph.D., assistant professor in the Department of Cancer Biology, and Rama Natarajan, Ph.D., director of the Division of Molecular Diabetes Research and the National Business Products Industry ...
  • September is Prostate Cancer Awareness Month. Here, Bertram Yuh, M.D., assistant clinical professor in the Division of Urology and Urologic Oncology at City of Hope, explains the importance of understanding the risk factors for the disease and ways to reduce those risks, as well as overall prostate health. “Wha...
  • ** Learn more about prostate health, plus prostate cancer research and treatment, at City of Hope. ** Learn more about getting a second opinion at City of Hope by visiting us online or by calling 800-826-HOPE (4673). City of Hope staff will explain what’s required for a consult at City of Hope and help yo...
  • Childhood cancer survival rates have increased dramatically over the past 40 years. More than 80 percent of children with cancer now survive five years or more, which is a tremendous feat. Despite the survival rate increase, cancer continues to be the No. 1 disease killer and second-leading cause of death in ch...
  • Although a stem cell transplant can be a lifesaving procedure for people diagnosed with a blood cancer or blood disorder, the standard transplant may not be appropriate for all patients. This is because the conditioning regimen (the intensive chemotherapy and/or radiation treatments preceding the transplant) is...
  • Brain tumor removal would seem to be the obvious course of action in the wake of a brain tumor diagnosis, but that’s not always the case. Some tumors are too difficult for many surgeons to reach or too close to areas that control vital functions. Removing them just proves too risky. A new device being con...