A National Cancer Institute-designated Comprehensive Cancer Center

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Beckman Research Institute Departments and Divisions

The Department of Cancer Biology offers a multidisciplinary research and training environment in molecular biology, genetics, epigenetics and developmental biology.
 
Dedicated to discovering immune-based cancer therapies, the Department of Cancer Immunotherapeutics & Tumor Immunology conducts research in a new and evolving field and is known particularly for its studies using genetically engineered T-cells.
 
This department focuses on understanding the genetic and molecular bases of diabetes, developing novel treatment approaches for diabetes and preventing associated diseases such as cancer, heart disease and stroke.
 
 
Immunology
With a dual focus on immunology and structural biology, the Department of Immunology explores cancer immunology and biochemistry, antigen processing and T cell development.
Maintaining a strong emphasis on the interface of chemistry and biology, the Department of Molecular and Cellular Biology focuses on gene structure, modeling of antibodies, theoretical biology and more.
Established in 1996, the Department of Molecular Medicine seeks to understand basic mechanisms underlying cancer and other diseases for the purpose of developing novel molecular therapeutics.
The Department of Molecular Pharmacology aims to bridge the gap between the development of promising new drugs and their application in the clinic.
 
The Department of Neurosciences focuses on a range of research related to the brain and nervous system, including studies of molecular neurobiology/neurochemistry, neurophysiology, neuromorphology and molecular genetics.
 
Department researchers collaborate to better understand the causes of cancer, improve outcomes and develop ways to prevent cancer through discoveries made in population studies, survivorship, patterns of care and more.
 
  • Division of Cancer Etiology
    The goal of the Division of Cancer Etiology is to understand the causes of cancer. By understanding the causes of cancer, solutions can be developed to help prevent cancer, especially in people who are at highest risk.
     
  • Division of Clinical Cancer Genetics
    The Division of Clinical Cancer Genetics includes clinical services, research, and educational programs focusing on people who are at increased risk for developing cancer because of family history or personal risk factors.
     
  • Division of Outcomes Research
    The goal of the Division of Outcomes Research is to better understand the after-effects (physical, emotional, and social) of cancer and its treatment.
    • Center for Cancer Survivorship
      This is a clinical long-term follow-up program designed to create a bridge between cancer treatment and community medical care.
       
  • Division of Nursing Research and Education
    The Division of Nursing Research and Education is well recognized on a national level for its research and education focused on nursing care for patients with cancer, which has helped to increase the quality of care provided to cancer patients across the United States.
The Department of Radiation Biology studies the fundamental mechanisms of cancers and radiation resistance in cancer cells to find a solution to improve the efficacy of radiation therapy.

Research in the Department of Virology supports eight faculty members and laboratories with research including viral vector development, viral immunology, and vaccine development. The program includes early phase clinical trials in gene transfer and in vaccine evaluation.

  • Translational Vaccine Research
    The Division of Translational Vaccine Research (TVR) develops vaccines to combat hematologic malignancies, solid tumors, and infectious pathogens such as CMV and HIV.
     
 

Departments and Divisions

Beckman Research Institute Departments and Divisions

The Department of Cancer Biology offers a multidisciplinary research and training environment in molecular biology, genetics, epigenetics and developmental biology.
 
Dedicated to discovering immune-based cancer therapies, the Department of Cancer Immunotherapeutics & Tumor Immunology conducts research in a new and evolving field and is known particularly for its studies using genetically engineered T-cells.
 
This department focuses on understanding the genetic and molecular bases of diabetes, developing novel treatment approaches for diabetes and preventing associated diseases such as cancer, heart disease and stroke.
 
 
Immunology
With a dual focus on immunology and structural biology, the Department of Immunology explores cancer immunology and biochemistry, antigen processing and T cell development.
Maintaining a strong emphasis on the interface of chemistry and biology, the Department of Molecular and Cellular Biology focuses on gene structure, modeling of antibodies, theoretical biology and more.
Established in 1996, the Department of Molecular Medicine seeks to understand basic mechanisms underlying cancer and other diseases for the purpose of developing novel molecular therapeutics.
The Department of Molecular Pharmacology aims to bridge the gap between the development of promising new drugs and their application in the clinic.
 
The Department of Neurosciences focuses on a range of research related to the brain and nervous system, including studies of molecular neurobiology/neurochemistry, neurophysiology, neuromorphology and molecular genetics.
 
Department researchers collaborate to better understand the causes of cancer, improve outcomes and develop ways to prevent cancer through discoveries made in population studies, survivorship, patterns of care and more.
 
  • Division of Cancer Etiology
    The goal of the Division of Cancer Etiology is to understand the causes of cancer. By understanding the causes of cancer, solutions can be developed to help prevent cancer, especially in people who are at highest risk.
     
  • Division of Clinical Cancer Genetics
    The Division of Clinical Cancer Genetics includes clinical services, research, and educational programs focusing on people who are at increased risk for developing cancer because of family history or personal risk factors.
     
  • Division of Outcomes Research
    The goal of the Division of Outcomes Research is to better understand the after-effects (physical, emotional, and social) of cancer and its treatment.
    • Center for Cancer Survivorship
      This is a clinical long-term follow-up program designed to create a bridge between cancer treatment and community medical care.
       
  • Division of Nursing Research and Education
    The Division of Nursing Research and Education is well recognized on a national level for its research and education focused on nursing care for patients with cancer, which has helped to increase the quality of care provided to cancer patients across the United States.
The Department of Radiation Biology studies the fundamental mechanisms of cancers and radiation resistance in cancer cells to find a solution to improve the efficacy of radiation therapy.

Research in the Department of Virology supports eight faculty members and laboratories with research including viral vector development, viral immunology, and vaccine development. The program includes early phase clinical trials in gene transfer and in vaccine evaluation.

  • Translational Vaccine Research
    The Division of Translational Vaccine Research (TVR) develops vaccines to combat hematologic malignancies, solid tumors, and infectious pathogens such as CMV and HIV.
     
 
Research Overview
Research pioneered at City of Hope has improved the lives of men, women and children throughout the world.
 
Beckman Research Institute

Beckman Research Institute of City of Hope is internationally  recognized for its innovative translational biomedical research.
 

Comprehensive Cancer Center
City of Hope is one of only 41 Comprehensive Cancer Centers in the country, the highest designation awarded by the National Cancer Institute to institutions that lead the way in cancer research, treatment, prevention and education.

Our Scientists

Our research laboratories are led by the best and brightest minds in scientific research.
 

Technology & Licensing
The Center for Applied Technology Development offers broad expertise in
technology transfer and licensing, biologics manufacturing, quality assurance and regulatory affairs.

Research Shared Services

City of Hope embodies the spirit of scientific collaboration by sharing services and core facilities with colleagues here and around the world.
 



NEWS & UPDATES
  • The body’s immune system is usually adept at attacking outside invaders such as bacteria and viruses. But because cancer originates from the body’s own cells, the immune system can fail to see it as foreign. As a result, the body’s most powerful ally can remain largely idle against cancer as the disease progres...
  • On Jan. 1, 2015, five City of Hope patients who have journeyed through cancer will welcome the new year with their loved ones atop City of Hope’s Tournament of Roses Parade float. The theme of the float is “Made Possible by HOPE.” The theme of the parade is “Inspiring Stories.” Her...
  • Are you thinking about switching from traditional cigarettes to e-cigarettes for the Great American Smokeout? Are you thinking that might be a better option than the traditional quit-smoking route? Think again. For lung expert Brian Tiep, M.D., the dislike and distrust he feels for e-cigs comes down to this: Th...
  • Hematologist Robert Chen, M.D., is boosting scientific discovery at City of Hope and, by extension, across the nation. Just ask the National Cancer Institute. The institution recently awarded Chen the much-sought-after Clinical Investigator Team Leadership Award for boosting scientific discovery at City of Hope...
  • Great strides have been made in treating cancer – including lung cancer – but by the time people show symptoms of the disease, the cancer has usually advanced. That’s because, at early stages, lung cancer has no symptoms. Only recently has lung cancer screening become an option. (Read more about the risks...
  • Identifying cures for currently incurable diseases and providing patients with safe, fast and potentially lifesaving treatments is the focus of City of Hope’s new Alpha Clinic for Cell Therapy and Innovation (ACT-I). The clinic is funded by an $8 million, five-year grant from the California Institute for Regene...
  • Cancer is a couple’s disease. It affects not just the person diagnosed, but his or her partner as well. It also affects the ability of both people to communicate effectively. The Couples Coping with Cancer Together program at City of Hope teaches couples how to communicate and solve problems as a unit. He...
  • Chemotherapy drugs work by either killing cancer cells or by stopping them from multiplying, that is, dividing. Some of the more powerful drugs used to treat cancer do their job by interfering with the cancer cells’ DNA and RNA growth, preventing them from copying themselves and dividing. Such drugs, however, l...
  • During October, everything seems to turn pink – clothing, the NFL logo, tape dispensers, boxing gloves, blenders, soup cans, you name it – in order to raise awareness for what many believe is the most dangerous cancer that affects women: breast cancer. But, in addition to thinking pink, women should...
  • In February 2003, when she was only 16 months old, Maya Gallardo was diagnosed with acute myelogenous leukemia (AML) and, to make matters much worse, pneumonia. The pneumonia complicated what was already destined to be grueling treatment regimen. To assess the extent of her illness, Maya had to endure a spinal ...
  • Former smokers age 55 to 74 who rely on Medicare for health care services have just received a long-hoped-for announcement. Under a proposed decision from the Centers for Medicare and Medicaid Services, they’ll now have access to lung cancer screening with a low-dose CT scan. The proposed decision, announ...
  • City of Hope has a longstanding commitment to combating diabetes, a leading national and global health threat. Already, it’s scored some successes, from research that led to the development of synthetic human insulin – still used by millions of patients – to potentially lifesaving islet cell transplants. Diabet...
  • Dee Hunt never smoked. Neither did her five sisters and brothers. They didn’t have exposure to radon or asbestos, either. That didn’t prevent every one of them from being diagnosed with lung cancer. Their parents were smokers, but they’d all left home more than 30 years before any of them were diagn...
  • They may not talk about it, but women with cancers in the pelvic region, such as cervical cancer, bladder cancer and uterine cancer, often have problems controlling their urine, bowel or flatus. Although they may feel isolated, they’re far from alone. Many other women have such problems, too. In fact, nea...
  • Cancer that spreads to the liver poses a significant threat to patients, and a great challenge to surgeons. The organ’s anatomical complexity and its maze of blood vessels make removal of tumors difficult, even for specialized liver cancer surgeons. Following chemotherapy, the livers of cancer patients are not ...