A National Cancer Institute-designated Comprehensive Cancer Center

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Beckman Research Institute Departments and Divisions

The Department of Cancer Biology offers a multidisciplinary research and training environment in molecular biology, genetics, epigenetics and developmental biology.
 
Dedicated to discovering immune-based cancer therapies, the Department of Cancer Immunotherapeutics & Tumor Immunology conducts research in a new and evolving field and is known particularly for its studies using genetically engineered T-cells.
 
This department focuses on understanding the genetic and molecular bases of diabetes, developing novel treatment approaches for diabetes and preventing associated diseases such as cancer, heart disease and stroke.
 
 
Immunology
With a dual focus on immunology and structural biology, the Department of Immunology explores cancer immunology and biochemistry, antigen processing and T cell development.
Maintaining a strong emphasis on the interface of chemistry and biology, the Department of Molecular and Cellular Biology focuses on gene structure, modeling of antibodies, theoretical biology and more.
Established in 1996, the Department of Molecular Medicine seeks to understand basic mechanisms underlying cancer and other diseases for the purpose of developing novel molecular therapeutics.
The Department of Molecular Pharmacology aims to bridge the gap between the development of promising new drugs and their application in the clinic.
 
The Department of Neurosciences focuses on a range of research related to the brain and nervous system, including studies of molecular neurobiology/neurochemistry, neurophysiology, neuromorphology and molecular genetics.
 
Department researchers collaborate to better understand the causes of cancer, improve outcomes and develop ways to prevent cancer through discoveries made in population studies, survivorship, patterns of care and more.
 
  • Division of Cancer Etiology
    The goal of the Division of Cancer Etiology is to understand the causes of cancer. By understanding the causes of cancer, solutions can be developed to help prevent cancer, especially in people who are at highest risk.
     
  • Division of Clinical Cancer Genetics
    The Division of Clinical Cancer Genetics includes clinical services, research, and educational programs focusing on people who are at increased risk for developing cancer because of family history or personal risk factors.
     
  • Division of Outcomes Research
    The goal of the Division of Outcomes Research is to better understand the after-effects (physical, emotional, and social) of cancer and its treatment.
    • Center for Cancer Survivorship
      This is a clinical long-term follow-up program designed to create a bridge between cancer treatment and community medical care.
       
  • Division of Nursing Research and Education
    The Division of Nursing Research and Education is well recognized on a national level for its research and education focused on nursing care for patients with cancer, which has helped to increase the quality of care provided to cancer patients across the United States.
The Department of Radiation Biology studies the fundamental mechanisms of cancers and radiation resistance in cancer cells to find a solution to improve the efficacy of radiation therapy.

Research in the Department of Virology supports eight faculty members and laboratories with research including viral vector development, viral immunology, and vaccine development. The program includes early phase clinical trials in gene transfer and in vaccine evaluation.

  • Translational Vaccine Research
    The Division of Translational Vaccine Research (TVR) develops vaccines to combat hematologic malignancies, solid tumors, and infectious pathogens such as CMV and HIV.
     
 

Departments and Divisions

Beckman Research Institute Departments and Divisions

The Department of Cancer Biology offers a multidisciplinary research and training environment in molecular biology, genetics, epigenetics and developmental biology.
 
Dedicated to discovering immune-based cancer therapies, the Department of Cancer Immunotherapeutics & Tumor Immunology conducts research in a new and evolving field and is known particularly for its studies using genetically engineered T-cells.
 
This department focuses on understanding the genetic and molecular bases of diabetes, developing novel treatment approaches for diabetes and preventing associated diseases such as cancer, heart disease and stroke.
 
 
Immunology
With a dual focus on immunology and structural biology, the Department of Immunology explores cancer immunology and biochemistry, antigen processing and T cell development.
Maintaining a strong emphasis on the interface of chemistry and biology, the Department of Molecular and Cellular Biology focuses on gene structure, modeling of antibodies, theoretical biology and more.
Established in 1996, the Department of Molecular Medicine seeks to understand basic mechanisms underlying cancer and other diseases for the purpose of developing novel molecular therapeutics.
The Department of Molecular Pharmacology aims to bridge the gap between the development of promising new drugs and their application in the clinic.
 
The Department of Neurosciences focuses on a range of research related to the brain and nervous system, including studies of molecular neurobiology/neurochemistry, neurophysiology, neuromorphology and molecular genetics.
 
Department researchers collaborate to better understand the causes of cancer, improve outcomes and develop ways to prevent cancer through discoveries made in population studies, survivorship, patterns of care and more.
 
  • Division of Cancer Etiology
    The goal of the Division of Cancer Etiology is to understand the causes of cancer. By understanding the causes of cancer, solutions can be developed to help prevent cancer, especially in people who are at highest risk.
     
  • Division of Clinical Cancer Genetics
    The Division of Clinical Cancer Genetics includes clinical services, research, and educational programs focusing on people who are at increased risk for developing cancer because of family history or personal risk factors.
     
  • Division of Outcomes Research
    The goal of the Division of Outcomes Research is to better understand the after-effects (physical, emotional, and social) of cancer and its treatment.
    • Center for Cancer Survivorship
      This is a clinical long-term follow-up program designed to create a bridge between cancer treatment and community medical care.
       
  • Division of Nursing Research and Education
    The Division of Nursing Research and Education is well recognized on a national level for its research and education focused on nursing care for patients with cancer, which has helped to increase the quality of care provided to cancer patients across the United States.
The Department of Radiation Biology studies the fundamental mechanisms of cancers and radiation resistance in cancer cells to find a solution to improve the efficacy of radiation therapy.

Research in the Department of Virology supports eight faculty members and laboratories with research including viral vector development, viral immunology, and vaccine development. The program includes early phase clinical trials in gene transfer and in vaccine evaluation.

  • Translational Vaccine Research
    The Division of Translational Vaccine Research (TVR) develops vaccines to combat hematologic malignancies, solid tumors, and infectious pathogens such as CMV and HIV.
     
 
Research Overview
Research pioneered at City of Hope has improved the lives of men, women and children throughout the world.
 
Beckman Research Institute

Beckman Research Institute of City of Hope is internationally  recognized for its innovative translational biomedical research.
 

Comprehensive Cancer Center
City of Hope is one of only 41 Comprehensive Cancer Centers in the country, the highest designation awarded by the National Cancer Institute to institutions that lead the way in cancer research, treatment, prevention and education.

Our Scientists

Our research laboratories are led by the best and brightest minds in scientific research.
 

Technology & Licensing
The Center for Applied Technology Development offers broad expertise in
technology transfer and licensing, biologics manufacturing, quality assurance and regulatory affairs.

Research Shared Services

City of Hope embodies the spirit of scientific collaboration by sharing services and core facilities with colleagues here and around the world.
 

NEWS & UPDATES
  • Cancer research has yielded scientific breakthroughs that offer patients more options, more hope for survival and a higher quality of life than ever before. The 14.5 million cancer patients living in the United States are living proof that cancer research saves lives. Now, in addition to the clinic, hospital an...
  • Advances in cancer treatment, built on discoveries made in the laboratory then brought to the bedside, have phenomenally changed the reality of living with a cancer diagnosis. More than any other time in history, people diagnosed with cancer are more likely to survive and to enjoy a high quality of life. Howeve...
  • While health care reform has led to an increase in the number of people signing up for health insurance, many people remain uninsured or are not taking full advantage of the health benefits they now have. Still others are finding that, although their premiums are affordable, they aren’t able to see the do...
  • Kidney cancer rates and thyroid cancer rates in adults have continued to rise year after year. Now a new study has found that incidence rates for these cancers are also increasing in children — particularly in African-American children. The study, published online this month in Pediatrics, examined childhood ca...
  • Thyroid cancer has become one of the fastest-growing cancers in the United States for both men and women. The chance of being diagnosed with the cancer has nearly doubled since 1990. This year an estimated 63,000 people will be diagnosed with thyroid cancer in the United States and nearly 1,900 people will die ...
  • Older teenagers and young adults traditionally face worse outcomes than younger children when diagnosed with brain cancer and other central nervous system tumors. A first-of-its-kind study shows why. A team of researchers from the departments of Population Sciences and Pathology at City of Hope recently examine...
  • Cancer treatment can take a toll on the mouth, even if a patient’s cancer has nothing to do with the head or throat, leading to a dry mouth, or a very sore mouth, and making it difficult to swallow or eat. Here’s some advice from the National Cancer Institute (NCI)  on how to ease cancer-related dis...
  • Radiation oncology is one of the three main specialties involved in the successful treatment of cancer, along with surgical oncology and medical oncology. Experts in this field, known as radiation oncologists, advise patients as to whether radiation therapy will be useful for their cancer – and how it can best ...
  • There’s more to cancer care than simply helping patients survive. There’s more to cancer treatment than simple survival. Constant pain should not be part of conquering cancer,  insists Betty Ferrell, Ph.D., R.N., director of nursing research and education at City of Hope. She wants patients and caregivers...
  • Even its name is daunting. Systemic mastocytosis is a fatal disease of the blood with no known cure. But a new study suggests a bone marrow transplant may be the answer for some patients. While rare, systemic mastocytosis is resistant to treatment with drugs and, when aggressive, can be fatal within four years ...
  • Could what you eat affect the health of your chromosomes? The short answer is, “Yes.” Researchers led by Dustin Schones, Ph.D., assistant professor in the Department of Cancer Biology, and Rama Natarajan, Ph.D., director of the Division of Molecular Diabetes Research and the National Business Products Industry ...
  • September is Prostate Cancer Awareness Month. Here, Bertram Yuh, M.D., assistant clinical professor in the Division of Urology and Urologic Oncology at City of Hope, explains the importance of understanding the risk factors for the disease and ways to reduce those risks, as well as overall prostate health. “Wha...
  • ** Learn more about prostate health, plus prostate cancer research and treatment, at City of Hope. ** Learn more about getting a second opinion at City of Hope by visiting us online or by calling 800-826-HOPE (4673). City of Hope staff will explain what’s required for a consult at City of Hope and help yo...
  • Childhood cancer survival rates have increased dramatically over the past 40 years. More than 80 percent of children with cancer now survive five years or more, which is a tremendous feat. Despite the survival rate increase, cancer continues to be the No. 1 disease killer and second-leading cause of death in ch...
  • Although a stem cell transplant can be a lifesaving procedure for people diagnosed with a blood cancer or blood disorder, the standard transplant may not be appropriate for all patients. This is because the conditioning regimen (the intensive chemotherapy and/or radiation treatments preceding the transplant) is...