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Supported by City of Hope's NCI-funded Cancer Center Support Grant (CCSG)

 Cancer Biology Publications, 2006

2006 - 2005 - 2004 - 2003 - 2002

Alexander NR, Tran NL, Rekapally H, Summers CE, Glackin C, Heimark RL. N-cadherin gene expression in prostate carcinoma is modulated by integrin-dependent nuclear translocation of Twist1. Cancer Research; 2006, 66(7): 3365-3369.

Chung V, Zhou B, Liu XY, Zhu L, Boo LM, Nguyen HV, Ann DK, Song J, Chen Y, Yen Y. SUMOylation plays a role in gemcitabine- and bortezomib-induced cytotoxicity in human oropharyngeal carcinoma KB gemcitabine-resistant clone. Molecular Cancer Therapeutics; 2006, 5(3): 533-540.

Dong M, Vongchampa V, Gingipalli L, Cloutier JF, Kow YW, O'Connor T, Dedon PC. Development of enzymatic probes of oxidative and nitrosative DNA damage caused by reactive nitrogen species. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis; 2006, 594(1-2): 120-134.

Gaur RK. RNA interference: a potential therapeutic tool for silencing splice isoforms linked to human diseases. Biotechniques; 2006, 40(4): 15-22.

Hill KA, Gonzalez KD, Scaringe WA, Wang JC, Sommer SS. Preferential occurrence of 1-2 microindels. Human Mutation; 2006, 27(1): 55-61.

Huang WD, Ma K, Zhang J, Qatanani M, Cuvillier J, Liu J, Dong BN, Huang XF, Moore DD. Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration. Science; 2006, 312(5771): 233-236.

Li CX, Kato M, Shiue L, Shively JE, Ares M, Lin RJ. Cell type and culture condition-dependent alternative splicing in human breast cancer cells revealed by splicing-sensitive microarrays. Cancer Research; 2006, 66(4): 1990-1999.

Li L, Yazaki PJ, Anderson AL, Crow D, Colcher D, Wu AM, Williams LE, Wong JY, Raubitschek A, Shively JE. Improved biodistribution and radioimmunoimaging with poly(ethylene glycol)-DOTA-conjugated anti-CEA diabody. Bioconjugate Chemistry; 2006, 17(1): 68-76.

Liu Q, Nguyen VQ, Li X, Sommer SS. Multiplex dosage pyrophosphorolysis-activated polymerization: application to the detection of heterozygous deletions. Biotechniques; 2006, 40(5): 661-668.

Liu R, Qiu JZ, Finger LD, Zheng L, Shen BH. The DNA-protein interaction modes of FEN-1 with gap substrates and their implication in preventing duplication mutations. Nucleic Acids Research; 2006, 34(6): 1772-1784.

Morris KV, Rossi JJ. Antiviral applications of RNAi. Current Opinion in Molecular Therapeutics; 2006, 8(2): 115-121.

Morris KV, Rossi JJ. Lentiviral-mediated delivery of siRNAs for antiviral therapy. Gene Therapy; 2006, 13(6): 553-558.

Nguyen HV, Chen JL, Zhong J, Kim KJ, Crandall ED, Borok Z, Chen Y, Ann DK. SUMOylation attenuates sensitivity toward hypoxia or desferroxamine-induced injury by modulating adaptive responses in salivary epithelial cells. American Journal of Pathology; 2006, 168(5): 1452-1463.

Pfeifer GP. Mutagenesis at methylated CpG sequences. DNA Methylation: Basic Mechanisms; 2006; 301: 259-281.

Reddy MA, Li SL, Sahar S, Kim YS, Xu ZG, Lanting L, Natarajan R. Key role of Src kinase in S100B-induced activation of the receptor for advanced glycation end products in vascular smooth muscle cells. Journal of Biological Chemistry; 2006, 281(19): 13685-13693.

Robbins MA, Li MJ, Leung I, Li HT, Boyer DV, Song Y, Behlke MA, Rossi JJ. Stable expression of shRNAs in human CD34(+) progenitor cells can avoid induction of interferon responses to siRNAs in vitro. Nature Biotechnology; 2006, 24(5): 566-571.

Rossi JJ. RNAi as a treatment for HIV-1 infection. Biotechniques; 2006, 40(4): 25-29.

Shi YH, Sun GQ, Stewart R. Nuclear receptors in stem cell biology. Critical Reviews in Eukaryotic Gene Expression; 2006, 16(2): 171-181.

Unwalla HJ, Li HT, Bahner I, Li MR, Kohn D, Rossi JJ. Novel Pol II fusion promoter directs human immunodeficiency virus type 1-inducible coexpression of a short hairpin RNA and protein. Journal of Virology; 2006, 80(4): 1863-1873.

Weinberg MS, Villeneuve LM, Ehsani A, Amarzguioui M, Aagaard L, Chen ZX, Riggs AD, Rossi JJ, Morris KV. The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells. Rna-a Publication of the Rna Society; 2006, 12(2): 256-262.

Winnard P, Glackin C, Raman V. Stable integration of an empty vector in MCF-7 cells greatly alters the karyotype. Cancer Genetics and Cytogenetics; 2006, 164(2): 174-176.

Xie ZH, Huang YN, Chen ZX, Riggs AD, Ding JP, Gowher H, Jeltsch A, Sasaki H, Hata K, Xu GL. Mutations in DNA methyltransferase DNMT3B in ICF syndrome affect its regulation by DNMT3L. Human Molecular Genetics; 2006, 15(9): 1375-1385.

Yoon JH, Qiu JZ, Cai S, Chen Y, Cheetham ME, Shen BH, Pfeifer GP. The retinitis pigmentosa-mutated RP2 protein exhibits exonuclease activity and translocates to the nucleus in response to DNA damage. Experimental Cell Research; 2006, 312(8): 1323-1334.

Li H, Rauch T, Chen ZX, Szabo PE, Riggs AD, Pfeifer GP. The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells. J Biol Chem; 2006;  :  .

Szabo PE, Han L, Hyo JJ, Mann JR. Mutagenesis in mice of nuclear hormone receptor binding sites in the Igf2/H19 imprinting control region. Cytogenet Genome Res; 2006, 113(1-4): 238-46.
Morris KV, Rossi JJ. Lentivirus-Mediated RNA Interference Therapy for Human Immunodeficiency Virus Type 1 Infection. Hum Gene Ther; 2006;  :  .

Jiang Z, Chu PG, Woda BA, Rock KL, Liu Q, Hsieh CC, Li C, Chen W, Duan HO, McDougal S, Wu CL. Analysis of RNA-binding protein IMP3 to predict metastasis and prognosis of renal-cell carcinoma: a retrospective study. Lancet Oncol; 2006, 7(7): 556-64.

Miao F, Li S, Chavez V, Lanting L, Natarajan R. Coactivator-associated arginine methyltransferase-1 enhances nuclear factor-kappaB-mediated gene transcription through methylation of histone H3 at arginine 17. Mol Endocrinol; 2006, 20(7): 1562-73.

Rodin SN, Rodin AS. Origin of the genetic code: first aminoacyl-tRNA synthetases could replace isofunctional ribozymes when only the second base of codons was established. DNA Cell Biol; 2006, 25(6): 365-75.

Smith DD, Kovats S, Lee TD, Cano L. Median filter algorithm for estimating the threshold of detection on custom protein arrays. Biotechniques; 2006, 41(1): 74-8.

Yam P, Jensen M, Akkina R, Anderson J, Villacres MC, Wu J, Zaia JA, Yee JK. Ex vivo selection and expansion of cells based on expression of a mutated inosine monophosphate dehydrogenase 2 after HIV vector transduction: effects on lymphocytes, monocytes, and CD34+ stem cells. Mol Ther; 2006, 14(2): 236-44.

Amarzguioui M, Lundberg P, Cantin E, Hagstrom J, Behlke MA, Rossi J. Rational design and in vitro and in vivo delivery of Dicer substrate siRNA. Nat. Protocols; 2006, 1(2): 508-517.

Benimetskaya L, Ayyanar K, Kornblum N, Castanotto D, Rossi J, Wu S, Lai J, Brown BD, Popova N, Miller P, McMicken H, Chen Y, Stein CA. Bcl-2 protein in 518A2 melanoma cells in vivo and in vitro. Clin Cancer Res; 2006, 12(16): 4940-8.

Kim DH, Villeneuve LM, Morris KV, Rossi JJ. Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells. Nat Struct Mol Biol; 2006, 13(9): 793-7.

Lacey SF, La RC, Zhou W, Sharma MC, Martinez J, Krishnan A, Gallez HG, Thao L, Longmate J, Longmate J, Spielberger R, Forman SJ, Limaye A, Zaia JA, Diamond DJ. Functional Comparison of T Cells Recognizing Cytomegalovirus pp65 and Intermediate-Early Antigen Polypeptides in Hematopoietic Stem-Cell Transplant and Solid Organ Transplant Recipients. J Infect Dis; 2006, 194(10): 1410-21.

Li SL, Reddy MA, Cai Q, Meng L, Yuan H, Lanting L, Natarajan R. Enhanced proatherogenic responses in macrophages and vascular smooth muscle cells derived from diabetic db/db mice. Diabetes; 2006, 55(9): 2611-9.

Paul S, Dansithong W, Kim D, Rossi J, Webster NJ, Comai L, Reddy S. Interaction of muscleblind, CUG-BP1 and hnRNP H proteins in DM1-associated aberrant IR splicing. Embo J; 2006, 25(18): 4271-83.

Rossi JJ. Partnering aptamer and RNAi technologies. Mol Ther; 2006, 14(4): 461-2.
Rossi JJ. Topical antiviral siRNA: A practical siRNA microbicide?. Gene Ther; 2006, 13(21): 1493-4.

Snove O, Rossi JJ. Chemical modifications rescue off-target effects of RNAi. Acs Chemical Biology; 2006, 1(5): 274-276.

Snove OJ, Rossi JJ. Toxicity in mice expressing short hairpin RNAs gives new insight into RNAi. Genome Biol; 2006, 7(8): 231.

Snove OJ, Rossi JJ. Expressing short hairpin RNAs in vivo. Nat Methods; 2006, 3(9): 689-95.

Soifer HS, Rossi JJ. Small interfering RNAs to the rescue: blocking L1 retrotransposition. Nat Struct Mol Biol; 2006, 13(9): 758-9.

Stiller M, Green RE, Ronan M, Simons JF, Du L, He W, Egholm M, Rothberg JM, Keats SG, Ovodov ND, Antipina EE, Baryshnikov GF, Kuzmin YV, Vasilevski AA, Wuenschell GE, Termini J, Hofreiter M, Jaenicke DV, Paabo S. Patterns of nucleotide misincorporations during enzymatic amplification and direct large-scale sequencing of ancient DNA. Proc Natl Acad Sci U S A; 2006, 103(37): 13578-84.

Zhang J, Ma C, Han X, Durrin LK, Sun Y. The bcl-2 major breakpoint region (mbr) possesses transcriptional regulatory function. Gene; 2006; 379: 127-31.

Ferl GZ, Kenanova V, Wu AM, DiStefano JJ. A two-tiered physiologically based model for dually labeled single-chain Fv-Fc antibody fragments. Molecular Cancer Therapeutics; 2006, 5(6): 1550-1558.

Chen S, Masri S, Hong Y, Wang X, Phung S, Yuan Y, Wu X. New experimental models for aromatase inhibitor resistance. In Press. J. Steroid Biochem & Mol Biol; 2006.

Chen S, Masri S, Wang X, Phung S, Yuan Y, Wu X. What do we know about the mechanisms of aromatase inhibitor resistance?  In press. J. Steroid Biochem. & Mol. Biol; 2006.

Gu Z, Olafsen T, Sherman M, Leyton J, Witkosky M, Shively J, Raubitschek A, Morrison S, Wu A, Reiter R. Targeting, Imaging, and Therapy using a Humanized Anti-Prostate Stem Cell Antigen (PSCA) Antibody. In Press. Journal of Immunotherapy; 2006.

Hong Y, Yu B, Sherman M, Yuan Y, Zhou D, Chen S. Molecular basis for the aromatization reaction and irreversible inhibition of human aromatases by exemestance. In press. Mol. Endocrinol; 2006.

Yang F, Huang X, YiT, Yen Y, Gonzales F, Moore D, Huang W. Spontaneous Development of Liver Tumors in The Absence of The Bile Acid Receptor FXR, CAN-06-1078. In Press. Cancer Research; 2006.

Cai S, Seu C, Kovacs Z, Sherry AD, Chen Y. Sensitivity enhancement of multidimensional NMR experiments by paramagnetic relaxation effects. J Am Chem Soc; 2006, 128(41): 13474-8.

Goswami SC, Yoon JH, Abramczyk BM, Pfeifer GP, Postel EH. Molecular and functional interactions between Escherichia coli nucleoside-diphosphate kinase and the uracil-DNA glycosylase Ung. J Biol Chem; 2006, 281(43): 32131-9.

Lee DH, Esworthy RS, Chu C, Pfeifer GP, Chu FF. Mutation accumulation in the intestine and colon of mice deficient in two intracellular glutathione peroxidases. Cancer Res; 2006, 66(20): 9845-51.

Shanmugam N, Ransohoff RM, Natarajan R. Interferon-gamma-inducible protein (IP)-10 mRNA stabilized by RNA-binding proteins in monocytes treated with S100b. J Biol Chem; 2006, 281(42): 31212-21.

Meyer D, Bailis A. Telomere dysfunction drives increased mutation by error-prone polymerases Rev1 and z in Saccharomyces cerevisiae. In press. Genetics; 2006.

Ito JI, Lyons JM, Hong TB, Tamae D, Liu YK, Wilczynski SP, Kalkum M. Vaccinations with recombinant variants of Aspergillus fumigatus allergen Asp f 3 protect mice against invasive aspergillosis. Infection and Immunity; 2006, 74(9): 5075-5084.

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