Therapeutic Prevention and Treatment Trials for High Risk Patients

• Targeted Treatments for Hereditary Breast or Ovarian Cancer (including PARP inhibitors)
  

  For information on a Phase II trial of Single Agent ABT-888 with Post-Progression Therapy of ABT-888 in Combination with Carboplatin in Patients with Stage IV BRCA-Associated Breast Cancer, please click on the following links
  
  CTOL (keyword search: 07211)
  
  ClinicalTrials.gov (search for study: NCT01149083)

• Cancer Prevention Trials and Other Studies for Postmenopausal Women

Laboratory Research
The major focus in the Clinical Cancer Genetics laboratory is molecular oncology and the investigation of molecular genetic changes associated with hereditary cancers.

Clinical and Behavioral Research

• Clinical Outcomes Research, Genetic Epidemiology
• Community Outreach and Health Services Research
• Ethical, Legal, and Social Implications in Society
• Education, Community Networks, and the Hereditary Cancer Registry

Hereditary Cancer Registry

The Cancer Screening & Prevention Program Network (CSPPN) is a network of City of Hope-affiliated genetic cancer risk assessment programs.  The multidisciplinary clinical cancer genetics team has developed an IRB-approved confidential registry (#96144:  Molecular Genetic Studies of Cancer Patients and Their Relatives), which allows patients who attend the CSPPN to participate in cancer genetics research.

Research Highlights
City of Hope's Clinical Cancer Genetics staff have authored a number of journal articles in publications such as Genetics in Medicine, American Journal of Human Genetics, Cancer Genetics, Journal of Genetic Counseling, Familial Cancer, Breast Cancer Research and Treatment, JAMA, Journal of Cancer Education, and Journal of Clinical Oncology.

Click here to download CCG's current list of publications. >>