We offer ultra high throughput DNA sequencing services on the Illumina HiSeq 2000 platform. Using a massively parallel sequencing approach, the Illumina HiSeq 2000 can generate up to 30GB of data in a single lane or up to 240 GB of data in a single run. The system uses Solexa sequencing technology and novel reversible terminator chemistry, optimized to achieve unprecedented levels of cost effectiveness and throughput. Learn more at Illumina's website >>

The 454 Genome Sequencer FLX Titanium platform generates about 1 million reads with an average length of 300-500bp in a typical run. It is an excellent platform for de novo sequencing and for projects that require longer read lengths. The GS FLX Titanium accommodates shotgun, paired-end, and amplicon sequencing runs. Learn more at the Roche 454 website >>

Applications

The following technologies have been developed for this platform:

• DNA-seq: de novo sequencing or resequencing
• ChIP-seq: DNA-protein interactions across the entire genome
• Methyl-seq: methylation profiling
• RNA-seq: mRNA expression, splicing, mutations/cSNP
• smRNA-seq: small RNA/miRNA discovery, profiling
• Structure variant detection: deletions, duplications, insertion, inversion and rearrangements
• Multiplexed Sample Sequencing with barcodes