We offer ultra high throughput DNA sequencing services on the Illumina Genome Analyzer II (formerly known as the Solexa) platform. Using a massively parallel sequencing approach, the Illumina GAII can generate up to 2 billion bases of data in a single lane or up to 16 billion bases of data in a single run. The system uses Solexa sequencing technology and novel reversible terminator chemistry, optimized to achieve unprecedented levels of cost effectiveness and throughput. More information describing this technology and its application is available at the Illumina Web site.
Applications
The following technologies have been developed for this platform:
- DNA-seq: de novo sequencing or re-sequencing
- ChIP-seq: DNA-protein interactions across the entire genome
- Methyl-seq: methylation profiling
- RNA-seq: mRNA expression, splicing, mutations/cSNP
- smRNA-seq: small RNA/miRNA discovery, profiling
- Structure variant detection: deletions, duplications, insertion, inversion and rearrangements
- Multiplexed Sample Sequencing with barcodes
