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Supported by City of Hope's NCI-funded Cancer Center Support Grant (CCSG)

 Biostatistics Core Facility

Director:  Jeffrey Longmate, Ph.D.
Co-Director: David Smith, Ph.D. 

The Biostatistics Core facility is a group of statisticians who collaborate in basic, translational, and clinical research in the Cancer Center.  The Core is supported by City of Hope’s NCI-funded Cancer Center Support Grant (CCSG), and its services are available to City of Hope researchers.

”The central requirement for successful collaboration is clear, broad, specific, two-way communication on both scientific issues and research roles.”

-- Moses and Thomas, Chapter 18 in Medical Uses of Statistics, 2nd ed., NEJM Books, 1992

Scientific Issues:  Areas of statistical expertise include: clinical trials; clinical epidemiology; genetic epidemiology; gene expression and functional genomics; pharmacokinetic modeling; assays, bioassays, and diagnostics; toxicology; and general statistical methods for data summary, inference and prediction;

Research Roles: Core members can help with study design, grant proposals, clinical protocols, data analysis, and manuscripts.

Services
Collaboration is our main activity.  The core statisticians generally contribute to the design and analysis of research projects as co-investigators and co-authors.   We collaborate in basic, translational, clinical and population-based research.

Consulting is available to advise investigators on statistical issues in research.  Consulting generally consists of one or two meetings, and it’s free.  This is a good way to explore possible collaboration, or just get statistical questions answered.

Case finding: The core can provide HIPAA-compliant identification of patients with stored tissue samples or other characteristics.

Statistical Computing is provided in conjunction with collaboration.

To access services or to use the facility, please contact us at 626-256-HOPE (4673), ext. 61444 or via email to schedule an appointment. 

Related Cores

The Biostatistics Core works closely with several other cores, including:

  • The Clinical Researh Information Support  (CRIS) Core delivers resources, education, and information and develops programs and processes to establish best practices in accordance with Good Clinical Practice (GCP).
  • The Clinical Research Informatics Core (CRIC), which provides clinical research database services, including electronic data capture.
  • The Bioinformatics Core, which, among other things, provides data files from gene expression microarrays and high through-put sequencing.

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 Shared Resources

City of Hope and Beckman Research Institute have developed Shared Resources where a perceived need exists for specialized equipment, services, or expert consultation. Shared Resources with specialized instrumentation, and the expertise to apply these resources to research, have become increasingly important in recent years. Many of City of Hope's research support services are funded by the Cancer Center Support Grant (CCSG). 

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