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Supported by City of Hope's NCI-funded Cancer Center Support Grant (CCSG)

 High Throughput Screening Core

Mission
The High Throughput Screening (HTS) Core’s mission is to assist City of Hope researchers in identifying novel lead compounds for anticancer drug development and chemical probes useful for biochemical mechanistic studies via sophisticated high throughput screening assays of synthetic compound and natural product libraries.

A team of medicinal chemists, pharmacologists, structural biologists, bioinformaticians and clinicians contributes valuable input to optimize some of these small molecules for drug development and translate them into clinical evaluation in cancer patients.

Compound Library
The core has a library of over 75,000 synthetic compounds that represent prime leads for drug development, as well as a library of over 7,000 natural product extracts comprising nearly 1 million individual compounds.

HTS Core Features Summary and Advantages
The HTS Core is a full-time, professionally-managed facility, boasting highly-trained and experienced staff, advanced equipment and a substantial compound library. These combined attributes and a centralized knowledge base increase cost effectiveness and productivity. Investigators also benefit from the cumulative experience gleaned from other projects in the High Throughput Screening Core.

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E-mail us for pricing or more information about the High Throughput Screening Core or to schedule an appointment for services or equipment.

Faculty & Staff

Location:
City of Hope
1500 East Duarte Road
Duarte, CA  91010-3000

Flower Building
Phone:  626-256-HOPE (4673), ext. 65057

NCI CCC LogoCity of Hope, An NCI-designated Comprehensive Cancer Center, is an innovative biomedical research, treatment and educational institution dedicated to the prevention and cure of cancer and other life-threatening illness.
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(NCCN), a not-for-profit alliance of 21 of the world’s leading cancer centers, is dedicated to improving the quality and effectiveness of care provided to patients with cancer.
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